Best TWAS P=8.51e-11 · Best GWAS P=2.03e-09 conditioned to 0.144
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TOP2B | 0.06 | 0.00 | enet | 11 | 0.00 | 3.3e-01 | -5.7 | 6.5 | 8.5e-11 | -0.78 | 0.04 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RARB | 0.07 | 0.03 | enet | 15 | 0.05 | 1.4e-05 | -5.6 | 6.3 | 3.0e-10 | -0.48 | 0.03 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TOP2B | 0.03 | 0.02 | blup | 73 | 0.01 | 1.2e-02 | -6.0 | 6.3 | 3.7e-10 | -0.90 | 0.02 | 0.94 | FALSE |