TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Platelet Count
:
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chr3:24,941,038-26,396,178
Best TWAS P=8.51e-11 · Best GWAS P=2.03e-09 conditioned to 0.144
25M
25.2M
25.4M
25.6M
25.8M
26M
26.2M
26.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
TOP2B
0.06
0.00
enet
11
0.00
3.3e-01
-5.7
6.5
8.5e-11
-0.78
0.04
0.88
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
RARB
0.07
0.03
enet
15
0.05
1.4e-05
-5.6
6.3
3.0e-10
-0.48
0.03
0.89
FALSE
3
The Cancer Genome Atlas
Thyroid Carcinoma
TOP2B
0.03
0.02
blup
73
0.01
1.2e-02
-6.0
6.3
3.7e-10
-0.90
0.02
0.94
FALSE