TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Blood Platelet Count
:
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chr3:26,563,909-28,450,371
Best TWAS P=7.42e-18 · Best GWAS P=4.14e-20 conditioned to 9.05e-11
26.5M
27M
27.5M
28M
28.5M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
NTR
Blood
EOMES
0.03
0.02
lasso
3
0.02
3.0e-08
8.4
8.6
7.4e-18
-0.03
0.90
0.10
TRUE
1
CommonMind
Brain Pre-frontal Cortex
NEK10
0.04
0.03
blup
450
0.03
9.5e-05
-5.5
6.2
6.7e-10
-0.71
0.24
0.67
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
EOMES
0.11
0.10
enet
10
0.10
1.3e-10
5.4
6.2
6.2e-10
0.08
0.96
0.04
FALSE