Best TWAS P=7.42e-18 · Best GWAS P=4.14e-20 conditioned to 9.05e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NEK10 | 0.04 | 0.03 | blup | 450 | 0.03 | 9.5e-05 | -5.5 | 6.2 | 6.7e-10 | -0.71 | 0.24 | 0.67 | TRUE |
| 2 | NTR | Blood | EOMES | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.0e-08 | 8.4 | 8.6 | 7.4e-18 | -0.03 | 0.90 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EOMES | 0.11 | 0.10 | enet | 10 | 0.10 | 1.3e-10 | 5.4 | 6.2 | 6.2e-10 | 0.08 | 0.96 | 0.04 | FALSE |