Best TWAS P=3.54e-12 · Best GWAS P=1.52e-14 conditioned to 0.00103
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NBEAL2 | 0.02 | 0.03 | lasso | 2 | 0.02 | 7.8e-04 | -7.7 | 7.0 | 3.5e-12 | -0.90 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | NBEAL2 | 0.07 | 0.03 | enet | 19 | 0.07 | 6.3e-06 | -7.7 | 5.4 | 6.7e-08 | -0.70 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Nerve Tibial | NBEAL2 | 0.19 | 0.14 | lasso | 5 | 0.17 | 3.1e-12 | -7.7 | 6.6 | 5.0e-11 | -0.89 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | NBEAL2 | 0.10 | 0.01 | enet | 22 | 0.04 | 3.3e-04 | -7.7 | 5.3 | 9.0e-08 | -0.63 | 0.00 | 0.85 | FALSE |