[Hub]/) : Traits : Blood Platelet Count :

chr3:36,624,134-40,143,794

Best TWAS P=7.75e-12 · Best GWAS P=1.46e-24 conditioned to 0.877

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ITGA9 0.39 0.18 lasso 5 0.21 8.8e-07 -6.2 5.9 3.4e-09 0.03 0.01 0.96 TRUE
2 GTEx Cells Transformed fibroblasts CSRNP1 0.12 0.02 lasso 4 0.02 6.0e-03 4.2 -6.8 7.8e-12 -0.47 0.24 0.32 TRUE
3 GTEx Cells Transformed fibroblasts SNORA62 0.14 0.04 lasso 5 0.02 1.5e-02 4.3 6.8 1.1e-11 0.45 0.06 0.79 FALSE
4 GTEx Skin Sun Exposed Lower leg SNORA6 0.09 0.02 enet 10 0.03 1.2e-03 3.6 -5.2 1.6e-07 -0.40 0.46 0.35 FALSE
5 ROSMAP Brain Pre-frontal Cortex TTC21A 0.21 0.10 blup 460 0.16 2.0e-20 4.2 5.2 2.0e-07 0.46 1.00 0.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRANK1 0.02 0.04 lasso 2 0.04 5.4e-05 -5.2 5.2 1.8e-07 0.04 0.01 0.96 TRUE
7 The Cancer Genome Atlas Lung Adenocarcinoma SCN11A 0.02 0.01 blup 77 0.02 3.6e-03 4.2 6.5 6.9e-11 0.57 0.03 0.60 TRUE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SCN11A 0.07 0.03 blup 79 0.05 4.8e-04 6.5 6.6 3.5e-11 0.63 0.01 0.98 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma SCN11A 0.05 0.03 blup 77 0.04 2.5e-05 3.9 5.7 9.3e-09 0.56 0.02 0.97 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma SCN11A 0.11 0.07 blup 77 0.07 9.4e-08 4.2 5.8 8.6e-09 0.49 0.89 0.10 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma WDR48 0.07 0.00 blup 66 0.01 1.3e-02 -0.7 5.9 4.1e-09 0.51 0.02 0.27 TRUE