Best TWAS P=6.22e-10 · Best GWAS P=2.23e-14 conditioned to 5.53e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | SIDT1 | 0.36 | 0.31 | enet | 21 | 0.33 | 6.2e-23 | 4.7 | -5.4 | 5.4e-08 | 0.70 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Nerve Tibial | WDR52 | 0.12 | 0.03 | lasso | 10 | 0.02 | 9.1e-03 | -5.4 | 5.4 | 7.4e-08 | -0.49 | 0.57 | 0.10 | FALSE |
| 3 | GTEx | Ovary | SIDT1 | 0.19 | -0.01 | lasso | 7 | -0.01 | 5.4e-01 | -5.2 | -5.4 | 5.6e-08 | 0.32 | 0.09 | 0.08 | FALSE |
| 4 | GTEx | Ovary | WDR52 | 0.21 | 0.26 | lasso | 9 | 0.23 | 1.9e-06 | -6.6 | 5.7 | 1.3e-08 | -0.81 | 0.03 | 0.90 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SIDT1 | 0.05 | 0.01 | blup | 87 | 0.03 | 1.1e-04 | 4.7 | -6.2 | 6.2e-10 | 0.75 | 0.06 | 0.82 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | SIDT1 | 0.11 | 0.03 | blup | 87 | 0.06 | 1.3e-06 | -5.7 | -5.8 | 7.0e-09 | 0.50 | 0.93 | 0.03 | FALSE |