Best TWAS P=1.71e-07 · Best GWAS P=1.74e-08 conditioned to 0.0344
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | HPGDS | 0.06 | 0.05 | lasso | 4 | 0.04 | 1.8e-06 | -5.2 | 5.2 | 1.7e-07 | -0.91 | 0.03 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HPGDS | 0.07 | 0.08 | blup | 54 | 0.10 | 2.8e-10 | -5.5 | 5.2 | 1.7e-07 | -0.96 | 0.02 | 0.98 | FALSE |