TWAS hub - NRD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.169	0.0710	2.0e-03	0.038	NA	0.043	NA	0.051	4.1e-04	NA	1.8e-04	NA	4.8e-05
2	GTEx	Cells Transformed fibroblasts	0.267	0.0550	2.3e-11	0.096	NA	0.191	NA	0.193	1.1e-07	NA	2.9e-14	NA	1.8e-14
3	GTEx	Esophagus Mucosa	0.307	0.0700	2.6e-08	0.140	NA	0.138	NA	0.171	1.4e-09	NA	1.7e-09	NA	1.4e-11
4	GTEx	Lung	0.130	0.0611	2.9e-03	-0.004	NA	0.038	NA	0.050	8.6e-01	NA	6.4e-04	NA	1.0e-04
5	GTEx	Nerve Tibial	0.289	0.0710	1.1e-06	0.158	NA	0.149	NA	0.182	2.5e-11	NA	1.1e-10	NA	6.1e-13
6	GTEx	Pancreas	0.121	0.0540	4.7e-03	0.092	NA	0.050	NA	0.084	1.1e-04	NA	3.6e-03	NA	2.0e-04
7	GTEx	Skin Sun Exposed Lower leg	0.084	0.0380	3.7e-03	0.000	NA	0.000	NA	0.003	3.2e-01	NA	2.9e-01	NA	1.8e-01
8	GTEx	Testis	0.122	0.0490	5.7e-04	0.163	NA	0.120	NA	-0.003	1.0e-07	NA	5.6e-06	NA	4.5e-01
9	GTEx	Whole Blood	0.084	0.0370	3.1e-04	0.026	NA	0.033	NA	0.033	1.6e-03	NA	5.1e-04	NA	4.4e-04
10	YFS	Blood	0.218	0.0423	0.0e+00	0.136	0.14	0.165	0.15	0.169	3.7e-42	1.7e-43	1.5e-51	9.9e-47	5.1e-53

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Supplements: Zinc	5.5	6.0	10.2	-1.9	-1.7	-3.2	-3.1	-3.1	-3.0	-2.3	-0.9	-1.5	-2.6
Sensitivity / hurt feelings	4.1	7.1	10.6	-3.0	-3.1	-3.0	-2.8	-3.3	-3.1	-3.3	0.7	-0.4	-1.9
Diabetes (father)	4.0	5.0	10.7	-3.1	-3.3	-1.8	-1.3	-2.3	-2.2	-3.1	1.8	1.2	-0.7
Hayfever/allergic rhinitis (self-reported)	3.9	5.2	8.1	2.6	2.6	2.6	2.3	2.8	2.8	2.5	-1.7	-0.7	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	3.5	5.3	18.7	-0.7	-2.6	0.6	1.3	0.3	0.1	-0.3	4.3	3.8	3.3
Risk taking	3.5	5.2	8.4	2.1	2.3	2.9	2.3	2.9	2.9	2.9	-0.8	0.4	1.6
Pack years adult smoking proportion	3.4	5.1	11.4	-3.4	-3.1	-2.1	-1.9	-2.6	-2.4	-2.5	1.4	1.0	-0.6
Bipolar Disorder (2018)	3.3	5.2	10.3	3.0	2.2	2.9	2.3	2.5	0.0	3.2	0.5	0.9	2.7
Ever used hormone-replacement therapy (HRT)	3.3	4.3	15.5	-0.6	-2.1	0.5	1.1	0.2	0.0	-0.1	3.8	3.9	2.6
Pack years of smoking	3.3	4.8	10.9	-3.3	-2.8	-2.1	-2.2	-2.6	-2.5	-2.3	0.8	0.6	-1.1
Suffer from ‘nerves’	3.1	4.9	9.3	-3.0	-2.8	-2.4	-1.7	-2.5	-2.3	-3.0	0.6	-0.5	-1.3
Neuroticism (Nagel 2018)	3.0	7.0	17.6	-4.2	-4.1	-1.7	-0.8	-2.4	-2.1	-3.0	3.1	1.7	0.5
Smoking status: Current	3.0	4.8	7.7	-2.8	-2.5	-2.6	-2.2	-2.3	-2.4	-2.3	1.7	1.5	-0.5
Irritability	3.0	5.0	10.3	-2.8	-3.2	-2.2	-2.0	-2.7	-2.6	-2.2	1.7	0.8	-0.3
Had menopause	2.8	3.5	9.9	-1.8	-3.1	-1.1	-1.0	-1.5	-1.6	-2.5	2.0	2.1	-0.4
Mineral and other dietary supplements	2.8	3.8	8.5	2.5	2.9	1.2	0.3	1.6	1.5	2.3	-2.7	-1.9	-0.6
Mood swings	2.7	5.0	17.7	-1.5	-3.0	0.0	0.5	-0.7	-0.8	-1.1	4.2	3.5	2.5
Eye problems/disorders: Cataract	2.7	3.1	7.9	2.8	2.8	1.0	0.2	1.0	0.9	2.5	-2.0	-1.3	-0.5
Breast cancer (self-reported)	2.7	3.2	11.3	3.4	2.2	1.9	1.3	1.8	1.5	1.8	-0.7	-0.2	1.2
Average weekly champagne plus white wine intake	2.7	3.8	9.0	0.3	-0.7	1.8	2.2	1.6	1.6	0.7	2.5	2.9	3.0
Neuroticism score	2.6	5.4	12.2	-3.5	-3.4	-1.9	-1.2	-2.5	-2.3	-3.1	2.0	0.8	-0.4
Alcohol drinker status: Never	2.6	3.1	9.0	-3.0	-2.1	-1.4	-1.1	-1.8	-1.7	-1.9	1.8	1.4	-0.1
Medication for hormone replacement therapy	2.5	2.8	6.6	-1.8	-2.6	-1.3	-1.0	-1.6	-1.6	-1.2	1.9	2.0	0.6
Serious illness, injury or assault to yourself	2.5	3.0	7.9	2.8	1.1	1.9	1.7	1.8	1.7	1.7	0.6	0.9	2.1
Hayfever, allergic rhinitis or eczema	2.5	5.5	8.0	2.2	1.3	2.8	2.8	2.7	2.7	2.3	1.1	1.8	2.8
Ovarian Cancer	2.4	3.2	5.8	1.4	-0.2	2.0	1.8	1.4	1.3	1.6	2.0	2.4	2.4
Neuroticism	2.4	5.7	15.3	-3.9	-3.8	-1.5	-0.9	-2.3	-2.0	-3.0	2.2	1.0	0.1
Number of operations (self-reported)	2.4	3.6	7.6	1.0	-0.1	2.4	2.2	1.6	1.6	1.4	1.9	2.4	2.8
Depression (Nagel 2018)	2.3	3.5	9.7	-1.0	-1.8	1.4	1.8	0.5	0.7	-0.2	3.1	2.6	2.9
Time employed in main current job	2.3	2.7	6.3	-0.8	-0.1	-1.8	-2.1	-1.7	-1.6	-1.0	-1.7	-1.8	-2.5
Fed-up feelings	2.2	3.9	6.7	-2.6	-2.6	-1.9	-1.5	-2.3	-2.2	-2.5	1.7	0.8	-0.5
Age at First Birth	2.1	3.1	7.3	2.7	2.1	1.2	0.6	1.7	1.6	2.4	-2.0	-1.4	0.1
Number of children fathered	2.1	2.4	3.7	-1.9	-0.7	-1.6	-1.9	-1.7	-1.7	-1.8	-0.5	-1.0	-1.8
Basal cell carcinoma (self-reported)	2.0	2.3	4.9	1.3	0.2	1.8	1.5	1.5	1.2	1.1	1.5	2.1	2.2
Depressed Affect (Nagel 2018)	1.9	3.9	8.9	-2.7	-3.0	-0.8	-0.2	-1.6	-1.4	-2.0	3.0	2.0	0.9
Schizophrenia vs Biploar Disorder	1.9	2.4	4.8	-2.2	-1.6	-1.6	-1.6	-2.0	0.0	-2.2	-0.2	-0.3	-1.8
Current tobacco smoking	1.9	3.1	5.8	-2.4	-1.9	-2.2	-1.9	-1.8	-2.0	-1.9	1.1	1.0	-0.6
Had other major operations	1.9	2.4	4.1	0.8	0.4	2.0	1.8	1.7	1.7	1.4	0.9	1.7	1.9
Qualifications: O levels/GCSEs or equivalent	1.9	3.1	5.5	2.4	1.5	1.7	2.2	2.0	2.1	1.8	-0.1	-0.6	1.5
Exposure to tobacco smoke outside home	1.9	2.6	7.8	-0.3	-0.5	1.9	1.3	1.2	1.2	1.1	1.9	2.8	2.1
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.8	-1.9	-2.2	-1.5	-1.1	-1.6	-1.6	-1.6	1.5	0.6	0.2
Heart disease (siblings)	1.9	2.3	5.1	-2.2	-1.9	-1.6	-1.6	-1.5	-1.6	-1.6	1.0	0.9	-0.3
HbA1C	1.8	2.0	3.6	-1.1	-1.4	-1.3	-1.3	-1.4	-1.7	-1.4	1.9	1.7	0.1
Prospective memory result	1.8	2.2	3.4	1.2	0.7	1.9	1.5	1.7	1.5	1.5	1.0	1.7	1.8
Age at first live birth	1.8	3.2	9.9	0.3	2.2	0.1	-0.5	0.7	0.7	1.2	-3.1	-2.9	-2.4
Commuting to job workplace: Car/motor vehicle	1.8	2.0	3.5	1.1	1.5	1.8	1.6	1.6	1.9	1.4	-1.6	-0.9	0.1
Medication: Paracetamol	1.8	2.7	5.9	1.6	1.1	2.4	1.9	2.1	2.2	1.8	-0.4	0.1	1.1
Supplements: Calcium	1.8	2.0	5.4	-1.4	-2.3	0.1	0.7	-0.6	-0.4	-1.8	2.2	1.8	1.0
Average weekly fortified wine intake	1.7	2.0	3.7	1.5	1.6	1.5	0.6	1.6	1.6	1.9	-1.7	-0.4	-0.1
Maternal smoking around birth	1.7	2.4	5.2	-1.7	-2.2	-1.1	-1.0	-1.7	-1.7	-2.3	1.6	1.0	-0.1
Nervous feelings	1.7	3.2	6.8	-2.6	-2.2	-1.9	-1.3	-2.0	-1.9	-2.6	0.7	-0.3	-1.0
Financial difficulties in last 2 years	1.7	2.3	7.4	0.3	-1.1	0.8	1.0	0.2	0.1	-0.2	2.7	2.4	2.7
Allergy	1.7	3.8	7.5	-2.2	-0.6	-1.9	-2.0	-2.0	-1.8	-1.7	-1.7	-2.2	-2.7
Qualifications: A levels/AS levels or equivalent	1.7	3.8	6.9	2.1	2.1	2.3	1.9	2.2	2.3	2.6	-1.0	-1.0	1.1
Medication: Paracetamol	1.7	2.8	6.0	1.6	1.3	2.5	2.0	2.1	2.3	1.6	-0.8	0.0	0.8
Medication: Blood pressure	1.7	3.0	6.0	-1.2	-2.5	-2.2	-2.1	-2.1	-2.1	-1.8	0.2	-0.4	-1.0
Illnesses of father: None of the above (group 1)	1.7	2.1	4.3	0.2	0.9	1.7	2.0	2.0	2.1	1.6	0.3	0.6	1.6
Ever depressed for a whole week	1.7	2.1	5.0	0.4	-0.3	1.7	2.0	1.3	1.4	0.3	1.7	1.5	2.2
Major Depression (MDD)	1.6	1.9	7.0	-0.3	-2.1	-0.2	0.2	-1.0	-0.9	-1.2	2.6	1.5	1.5
Severe depression (siblings)	1.6	1.8	3.3	1.0	1.4	1.6	1.4	1.8	1.8	1.3	-0.1	0.2	1.5
Past tobacco smoking	1.6	3.0	10.3	0.9	1.9	-0.0	-0.1	0.1	0.3	-0.3	-3.0	-3.2	-2.3
Qualifications: College or University degree	1.6	4.9	8.9	2.4	3.0	2.1	1.9	2.2	2.4	2.4	-2.3	-2.1	0.2
Medication: Seretide 50 evohaler	1.6	1.9	3.4	1.5	1.6	1.7	1.3	1.8	1.7	1.4	0.0	0.8	0.7
Age at last live birth	1.6	2.3	4.9	1.1	2.2	1.4	0.5	1.4	1.4	2.1	-2.0	-1.4	-0.5
Worry (Nagel 2018)	1.5	3.2	9.6	-3.1	-2.9	-1.0	-0.4	-1.5	-1.2	-2.1	1.8	0.9	0.2
LDL Cholesterol	1.5	2.4	6.9	-1.4	-1.5	-0.6	-1.1	-1.2	-1.5	-1.1	2.6	2.6	0.7
Diabetes (mother)	1.5	1.9	4.3	1.1	1.8	1.4	1.0	1.8	1.5	2.1	-0.1	1.1	0.7
Lupus	1.4	2.2	7.1	-2.7	-1.3	-1.2	-1.4	-1.3	-1.3	-1.9	0.8	0.9	-0.8
Average weekly spirits intake	1.4	1.7	5.1	0.3	-0.1	-0.6	-1.2	-0.8	-0.7	-0.7	-2.1	-2.3	-1.9
Frequency of depressed mood in last 2 weeks	1.4	1.9	6.3	-1.3	-1.7	0.5	0.9	-0.4	-0.2	-1.3	2.5	1.7	1.5
Headache pain in last month	1.4	2.4	6.2	1.6	1.9	1.4	0.8	1.2	1.4	1.3	-2.5	-1.6	-0.7
Leg pain on walking	1.4	1.8	5.5	2.3	1.3	1.4	1.2	1.5	1.5	1.0	-1.1	-0.9	0.2
Fractured/broken bones in last 5 years	1.4	1.9	5.8	1.1	-0.2	1.0	1.0	0.5	0.3	0.2	2.3	2.4	2.0
Vitamin and mineral supplements	1.3	1.7	4.6	1.1	1.9	-0.3	-1.0	-0.0	-0.2	1.0	-2.1	-1.8	-1.5
Impedance of leg (right)	1.3	6.3	12.5	-3.2	-3.5	-2.6	-1.5	-2.7	-2.7	-2.4	2.6	1.8	0.0
Depression (self-reported)	1.3	1.5	4.0	-1.6	-2.0	-0.2	-0.0	-0.7	-0.6	-1.6	1.6	1.3	0.7
Wears glasses or contact lenses	1.3	1.5	3.4	-1.3	-1.9	-0.9	-0.7	-1.2	-1.2	-1.6	1.5	1.0	0.0
Triglycerides	1.2	2.0	4.3	0.6	-0.3	1.5	1.6	1.1	1.1	0.2	1.9	2.1	2.0
Ever had hysterectomy (womb removed)	1.2	1.4	4.1	0.9	-0.1	0.9	1.0	0.9	0.7	0.7	1.7	1.7	2.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	4.8	-0.4	-1.0	1.0	1.4	0.7	0.7	0.1	2.2	2.0	2.1
Qualifications: None of the above	1.2	2.7	4.6	-2.1	-1.4	-1.8	-2.0	-2.0	-2.1	-1.4	1.0	0.8	-0.8
Mouth/teeth dental problems	1.2	1.9	5.6	1.6	2.0	0.7	0.8	1.3	1.3	2.4	-0.9	-0.8	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.3	-1.1	-0.7	-1.3	-1.3	-1.0	-1.0	-1.8	-0.8	-0.9	-1.8
Ulcerative Colitis (UC)	1.1	2.0	4.0	2.0	2.0	1.0	0.9	1.8	1.6	1.6	-1.3	-0.3	0.4
Mean Putamen Volume	1.1	1.3	3.9	0.9	0.5	0.3	0.1	0.5	0.1	1.4	1.6	1.6	2.0
Schizophrenia (2014)	1.1	2.5	5.3	-2.2	-1.1	-1.9	-2.3	-2.0	0.0	-1.6	-0.2	-0.3	-1.8
Pain all over the body in last month	1.1	1.1	2.5	0.9	0.1	1.1	0.9	0.9	0.8	1.0	1.3	1.6	1.4
Knee pain experienced in last month	1.1	1.8	3.3	1.7	1.1	1.8	1.5	1.8	1.7	0.8	0.0	0.7	0.9
Diabetes diagnosed by doctor	1.1	1.8	3.8	0.2	0.2	1.9	1.9	1.4	1.5	0.6	1.1	1.4	1.6
Friendships satisfaction	1.1	1.3	2.6	-0.5	-0.6	-1.5	-1.6	-1.2	-1.2	-0.7	-0.9	-1.1	-1.6
Qualifications: nursing, teaching	1.1	1.7	2.6	1.1	1.3	1.6	1.5	1.4	1.6	1.4	-1.1	-1.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	5.4	2.3	2.2	0.8	0.2	1.3	1.1	2.2	-1.9	-1.3	-0.1
Ever smoked	1.1	2.0	6.5	-0.7	-1.5	0.0	0.2	0.2	0.0	0.6	2.3	2.5	2.2
Medication: Co-codamol	1.0	1.1	3.3	0.5	-0.6	0.3	0.7	0.7	0.5	-0.5	1.6	1.7	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	3.8	-1.1	-1.6	0.5	0.8	-0.2	-0.0	-0.4	1.9	1.6	1.4
Lung cancer (father)	1.0	1.1	2.4	-1.3	-1.0	1.1	1.3	0.5	0.7	-0.1	1.2	1.6	1.0
Worry too long after embarrassment	1.0	1.7	4.7	-2.2	-2.0	-0.9	-0.5	-1.3	-1.1	-1.7	1.3	0.3	0.3
Medication: Omeprazole	1.0	1.1	3.3	0.5	-0.8	0.9	1.0	0.6	0.6	0.3	1.4	1.8	1.6
Heart disease (mother)	1.0	1.3	2.3	0.1	-0.1	1.5	1.5	1.2	1.1	0.6	1.2	1.2	1.5
Smoking status: Previous	1.0	1.5	3.4	0.7	-0.1	1.2	0.9	0.9	0.8	1.6	1.3	1.8	1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	6.7	1.4	1.2	-0.1	-0.7	0.1	0.1	0.7	-2.6	-2.3	-1.9
Miserableness	1.0	1.7	4.8	-1.6	-1.7	-0.8	-0.3	-1.1	-1.1	-1.0	2.2	1.5	0.9
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.7	-1.6	-1.6	-0.8	-0.3	-0.8	-0.8	-1.5	1.4	1.2	0.1
Diastolic blood pressure, automated reading	1.0	3.2	8.4	1.2	1.6	-1.5	-2.0	-0.6	-0.8	0.6	-2.9	-2.1	-2.7
Myopia	1.0	1.4	4.0	1.1	1.6	-0.4	-0.7	0.1	0.0	1.1	-2.0	-1.7	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.3	0.9	-0.5	0.9	1.0	0.7	0.7	0.6	1.2	1.8	1.6
Alzheimer’s Disease (in father)	0.9	1.0	2.0	-1.2	-0.6	-1.4	-1.0	-1.1	-1.0	-0.7	-0.5	-0.6	-1.1
Irritable Bowel Disease (IBD)	0.9	2.2	4.9	2.2	2.0	1.2	1.1	1.7	1.6	1.7	-1.3	-0.6	0.5
Body Mass Index (BMI) (2010)	0.9	1.2	2.6	1.1	1.2	1.6	1.4	1.4	1.4	1.0	-0.6	-0.2	0.3
Allergy or Eczema	0.9	2.5	6.0	0.4	-0.1	1.7	1.8	1.5	1.5	0.8	1.8	2.1	2.4
Number of incorrect matches in round	0.9	1.5	3.3	0.2	-1.4	-1.7	-1.8	-1.4	-1.7	-1.1	0.6	0.2	-0.3
Fluid intelligence score	0.9	1.8	4.5	-2.0	-2.1	-0.9	-0.6	-1.2	-1.2	-1.7	1.2	1.2	-0.2
Noisy workplace	0.9	1.1	2.1	0.1	0.7	-1.0	-1.2	-1.1	-1.2	-1.2	-0.6	-1.4	-1.4
Medication: Lansoprazole	0.9	1.0	2.3	0.2	-0.2	1.3	1.2	0.8	0.9	1.1	1.1	1.2	1.5
Exposure to tobacco smoke at home	0.9	1.0	3.4	0.1	-1.0	0.4	0.3	0.0	-0.2	-0.2	1.9	1.8	1.6
Medication: Amlodipine	0.9	1.3	2.3	-0.7	-1.3	-1.5	-1.3	-1.5	-1.5	-1.1	0.0	-0.6	-0.7
Number of full brothers	0.9	1.1	2.8	0.8	1.3	0.8	0.7	1.1	1.3	1.3	-1.7	-0.8	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	3.0	0.5	-0.9	1.1	0.7	0.5	0.5	0.4	1.1	1.7	1.3
Medication for cholesterol	0.9	1.4	2.2	1.1	1.5	1.2	0.9	1.5	1.4	1.1	-1.3	-1.1	0.2
Commuting to job workplace: Cycle	0.9	1.1	2.6	-0.1	0.2	-1.2	-1.6	-0.8	-0.9	-0.1	-1.3	-1.2	-1.6
Crohns Disease (2012)	0.8	1.4	3.1	1.5	1.8	1.0	0.8	1.2	0.0	1.6	-1.3	-0.9	-0.1
Blood Platelet Count	0.8	9.7	35.4	-0.1	-2.9	0.9	1.3	0.5	0.1	-0.5	5.6	6.0	4.4
Smoking Status	0.8	1.9	7.6	-1.2	-1.5	-0.8	-1.0	-0.5	-0.8	0.0	2.0	2.8	0.9
Respiratory disease	0.8	1.9	3.2	-0.5	-1.0	-1.6	-1.8	-1.7	-1.8	-1.8	0.0	-0.5	-1.3
Diabetes (self-reported)	0.8	1.3	2.8	0.2	0.2	1.7	1.5	1.0	1.1	0.8	1.0	1.4	1.4
Pulse rate	0.8	1.3	2.9	-0.9	-1.3	-0.8	-0.5	-1.1	-1.2	-0.7	1.7	1.7	0.6
High blood pressure (siblings)	0.8	1.1	2.5	1.6	1.3	0.5	0.4	1.0	0.9	1.6	-1.1	-1.0	0.2
Illnesses of father: Heart disease	0.8	1.1	1.9	0.3	-0.3	-0.8	-1.2	-1.3	-1.3	-0.7	-1.1	-1.2	-1.4
Hearing aid user	0.8	0.9	3.0	-0.1	-1.0	0.1	0.2	0.1	-0.1	-0.1	1.7	1.6	1.3
Medication: Atorvastatin	0.8	1.0	3.1	-0.1	0.0	1.0	1.8	1.0	1.1	-0.2	1.0	0.6	1.3
Verbal and Numeric Reasoning (VNR)	0.7	1.8	4.6	-1.6	-2.1	-0.5	0.1	-0.7	-0.8	-1.7	2.0	1.5	0.7
Waist Hip Ratio (WHR)	0.7	3.2	5.6	-2.1	-2.4	-1.8	-1.7	-2.2	-2.2	-1.8	1.4	0.8	-0.5
Townsend deprivation index at recruitment	0.7	1.0	3.0	-0.1	-1.2	-1.0	-0.5	-0.9	-1.1	-0.5	1.7	1.3	1.0
Multivitamins +/- minerals	0.7	0.9	2.8	-0.7	-1.7	0.0	0.5	-0.1	-0.0	-0.7	1.5	1.4	1.1
Father’s age at death	0.7	0.9	3.1	0.1	0.5	-0.6	-0.8	-0.7	-0.6	-0.4	-1.2	-1.8	-1.5
Hair/balding pattern: Pattern 3	0.7	1.1	3.2	0.7	0.9	-0.6	-0.6	-0.5	-0.3	-0.1	-1.7	-1.8	-1.5
Pulse wave Arterial Stiffness index	0.7	0.8	2.5	-1.0	-0.8	0.5	0.3	0.0	0.0	-0.7	1.4	1.6	0.9
Gout (self-reported)	0.7	0.9	2.6	-0.1	-1.2	0.2	1.0	0.3	0.3	-0.3	1.5	1.2	1.6
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.7	-0.4	-1.4	-0.3	-0.1	-0.7	-0.7	-1.9	0.9	0.3	0.2
Pulse wave peak to peak time	0.7	0.9	2.7	0.9	0.6	-0.6	-0.6	-0.2	-0.2	0.5	-1.6	-1.6	-1.1
Mean time to correctly identify matches	0.7	1.3	3.2	-0.3	-0.0	-1.1	-1.6	-1.0	-1.1	-0.4	-1.2	-1.6	-1.8
Overall health rating	0.7	1.5	2.8	0.8	-0.4	1.5	1.5	1.3	1.2	0.3	1.3	1.7	1.5
Family relationship satisfaction	0.7	0.8	1.7	-0.5	-0.2	-1.2	-1.3	-1.2	-1.1	-0.5	-0.5	-0.8	-1.1
Illnesses of siblings: Diabetes	0.7	0.9	2.6	0.3	0.1	1.2	1.6	1.1	1.1	0.2	0.6	0.7	1.2
Leg fat-free mass (right)	0.7	3.7	11.7	1.9	2.4	1.1	-0.4	1.3	1.3	1.5	-3.4	-2.4	-1.9
Loneliness, isolation	0.7	0.9	2.5	-1.4	-1.6	-0.4	-0.3	-0.7	-0.7	-1.4	0.9	0.7	-0.4
Leg predicted mass (right)	0.7	3.8	11.6	2.0	2.4	1.1	-0.3	1.4	1.3	1.5	-3.4	-2.4	-1.8
Number of self-reported non-cancer illnesses	0.7	1.3	2.5	1.6	0.3	1.3	1.1	1.0	1.0	1.0	0.8	1.1	1.5
Guilty feelings	0.7	1.0	2.8	-1.7	-1.3	-1.0	-0.3	-1.0	-0.8	-1.5	0.2	-0.5	-0.6
Mother’s age at death	0.7	0.9	3.3	-0.2	0.3	-0.9	-0.7	-0.6	-0.5	0.2	-1.3	-1.8	-1.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.9	0.8	0.8	1.2	0.7	1.2	1.4	1.0	-1.0	0.2	-0.1
Illnesses of father: High blood pressure	0.7	0.9	1.9	0.9	0.1	-1.1	-1.0	-0.9	-1.0	-0.6	-0.6	-1.4	-1.2
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.9	-0.0	0.8	0.1	-0.2	-0.0	0.2	0.4	-1.7	-1.7	-1.0
Schizophrenia (2018)	0.6	1.2	2.5	-1.4	-0.8	-1.3	-1.6	-1.3	0.0	-1.3	-0.1	0.1	-1.4
Rheumatoid Arthritis	0.6	0.9	2.6	0.4	-0.0	1.6	1.6	1.1	0.0	0.7	0.3	0.5	1.1
Ulcerative Colitis	0.6	0.8	1.8	1.2	1.1	0.9	0.7	1.2	0.0	0.4	-1.4	-0.8	-0.4
BMI	0.6	3.2	11.8	0.8	2.3	0.3	-0.4	0.7	0.8	0.8	-3.4	-2.8	-2.0
Taking other prescription medications	0.6	1.0	3.3	1.0	-0.5	0.7	0.8	0.3	0.3	0.1	1.4	1.3	1.8
Medication: Atenolol	0.6	0.8	2.2	0.9	0.2	0.7	0.5	1.1	1.1	1.5	-1.0	-0.3	0.7
Impedance of leg (left)	0.6	3.0	5.6	-2.4	-2.3	-1.9	-1.1	-1.9	-1.9	-1.3	1.8	1.4	-0.0
Hip circumference	0.6	2.4	9.1	0.9	1.7	0.1	-0.5	0.7	0.8	0.7	-3.0	-2.4	-2.0
Worrier / anxious feelings	0.6	1.2	3.2	-1.7	-1.8	-0.9	-0.6	-1.1	-1.0	-1.4	0.7	0.0	-0.4
Mouth/teeth dental problems: Dentures	0.6	1.1	3.4	-1.9	-1.2	-0.7	-0.6	-1.0	-0.9	-1.5	0.5	0.6	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.9	0.0	0.7	0.4	-0.1	0.4	0.6	0.8	-1.7	-1.2	-1.0
Peak expiratory flow (PEF)	0.6	1.3	3.2	1.2	1.4	1.1	0.1	1.2	1.1	1.8	-1.5	-0.1	-0.1
Pulse wave reflection index	0.6	0.8	1.7	0.6	1.1	0.9	0.5	1.0	1.1	0.4	-1.3	-0.6	-0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.3	-0.5	-1.5	-0.2	-0.3	-0.6	-0.7	-1.1	1.0	0.9	0.6
Medication: Ibuprofen	0.6	0.8	2.2	0.6	0.8	1.0	0.5	1.0	1.1	1.5	-0.9	-0.5	0.0
Comparative height size at age 10	0.6	3.2	7.9	-0.8	-1.4	-1.7	-2.7	-1.6	-1.7	-1.6	-1.4	-0.6	-2.8
Had major operations	0.6	0.7	1.9	0.0	-0.4	0.9	0.7	0.7	0.6	0.4	1.0	1.2	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.3	0.2	-0.1	1.0	1.1	0.8	0.9	0.3	0.6	1.2	1.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.4	-0.9	-1.0	-0.8	-0.9	-1.2	-1.1	-0.2	-0.1	-0.4	-0.7
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.7	-0.8	-1.0	0.7	1.4	0.5	0.6	-0.2	1.9	1.8	1.6
Fasting Glucose	0.5	0.6	1.7	0.1	0.9	0.7	0.3	0.3	0.5	0.1	-1.3	-0.9	-1.2
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.9	0.8	1.1	1.4	1.4	1.2	1.3	0.9	-0.2	-0.0	0.6
Hand grip strength (left)	0.5	1.3	3.8	-0.8	0.1	-1.1	-1.4	-0.8	-0.8	-1.0	-1.2	-1.3	-1.9
Leg fat-free mass (left)	0.5	2.5	8.9	1.3	1.6	0.6	-0.7	0.9	0.8	0.8	-3.0	-2.1	-2.0
Stomach or abdominal pain in last month	0.5	0.6	1.9	0.8	-0.3	0.6	0.7	0.3	0.4	0.5	1.1	0.9	1.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.4	-0.9	-0.8	-0.5	-0.5	-1.0	-1.1	-0.7	1.2	0.4	0.1
Body mass index (BMI)	0.5	2.1	5.5	1.3	2.1	0.9	0.4	1.3	1.4	1.2	-2.4	-1.7	-0.9
Alcohol intake versus 10 years previously	0.5	0.7	1.9	-0.3	0.4	-1.0	-0.9	-1.0	-0.9	0.1	-0.9	-1.4	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	3.8	1.4	1.4	0.8	-0.0	0.9	0.9	1.7	-2.0	-1.2	-0.6
Arm fat mass (right)	0.5	2.0	7.0	1.1	1.8	0.5	-0.2	1.0	1.0	1.0	-2.6	-1.8	-1.5
Standing height	0.5	4.7	10.0	-1.8	-2.1	-2.0	-3.1	-2.1	-2.1	-2.0	-1.5	-0.9	-3.2
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.9	1.3	0.5	0.1	-0.3	0.1	0.1	-0.1	-1.3	-1.4	-0.7
Glaucoma (self-reported)	0.5	0.6	1.2	-0.7	-0.4	-0.5	-0.6	-1.1	-0.9	-0.5	-0.4	-0.9	-1.1
Health satisfaction	0.5	0.6	1.6	1.2	0.9	0.5	0.0	0.7	0.6	1.0	-0.9	-0.9	-0.0
Emphysema/chronic bronchitis	0.5	0.6	2.0	0.4	0.7	-0.7	-1.1	-0.3	-0.5	-0.1	-0.9	-0.5	-1.4
Migraine (self-reported)	0.5	0.6	1.7	-0.4	0.4	-0.1	-0.8	-0.4	-0.3	0.5	-1.2	-0.9	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	2.0	0.0	-0.4	0.4	0.8	0.5	0.5	-0.0	1.1	1.4	0.8
Number of full sisters	0.5	0.6	2.6	0.6	-0.6	0.1	0.2	0.3	0.1	0.4	1.1	1.0	1.6
Arm fat percentage (left)	0.5	1.9	4.0	1.2	1.9	0.9	0.6	1.5	1.5	1.5	-2.0	-1.2	-0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.3	0.0	-0.9	-0.9	-1.0	-1.1	-1.2	-0.5	0.8	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.0	1.0	-0.1	1.4	1.3	0.9	0.9	0.2	0.6	0.8	0.7
Osteoarthritis (self-reported)	0.5	0.7	1.7	0.7	0.6	1.3	1.3	1.0	1.1	-0.1	-0.6	-0.3	-0.1
Medication: Gliclazide	0.5	0.6	1.6	0.4	1.1	0.4	0.5	0.5	0.6	0.3	-1.0	-1.3	-0.7
Arm fat-free mass (left)	0.5	2.4	7.3	-0.3	0.1	-0.7	-2.0	-0.8	-0.7	-0.7	-2.5	-2.0	-2.7
Impedance of whole body	0.5	2.6	5.0	-2.2	-2.2	-1.8	-0.8	-1.7	-1.7	-1.1	1.7	1.3	0.2
Leg fat mass (left)	0.5	1.8	6.2	1.0	1.7	0.4	-0.2	1.1	1.1	1.1	-2.5	-1.4	-1.4
Arm predicted mass (left)	0.5	2.4	7.8	-0.3	0.1	-0.8	-2.1	-0.8	-0.8	-0.6	-2.5	-1.9	-2.8
Prostate Cancer	0.4	0.6	2.0	0.5	0.9	0.5	-0.2	0.6	0.5	0.3	-1.4	-0.8	-1.2
Coronary Artery Disease (CAD)	0.4	0.5	1.6	1.3	0.2	0.4	0.6	0.6	0.4	0.7	0.4	0.3	1.1
Neuroticism (2016)	0.4	0.5	1.5	-0.4	-1.0	-0.1	0.4	-0.3	-0.2	-0.9	1.2	0.8	0.9
Cardiovascular Disease	0.4	1.4	4.2	1.5	1.7	0.0	-0.3	0.4	0.3	1.1	-2.0	-1.4	-1.1
Lung FVC	0.4	2.2	4.8	2.2	1.7	1.2	1.0	1.5	1.4	2.0	-1.4	-1.2	0.4
Systolic blood pressure, automated reading	0.4	1.3	2.9	0.3	-0.9	-1.6	-1.7	-1.2	-1.6	-0.9	0.8	0.8	-0.5
Medication: Metformin	0.4	0.6	1.7	-0.2	0.4	1.2	1.3	0.9	1.1	0.2	0.1	0.1	0.5
Leg predicted mass (left)	0.4	2.3	8.6	1.3	1.6	0.5	-0.8	0.8	0.8	0.8	-2.9	-2.1	-1.9
Trunk fat mass	0.4	1.5	6.4	0.6	1.3	0.2	-0.4	0.7	0.8	0.8	-2.5	-1.5	-1.7
Waist circumference	0.4	1.4	4.0	-0.1	0.2	-0.9	-1.3	-0.5	-0.5	-0.5	-2.0	-1.6	-2.0
Weight	0.4	2.1	8.6	0.4	1.1	-0.0	-1.0	0.4	0.4	0.3	-2.9	-2.0	-2.3
Arm fat percentage (right)	0.4	1.7	5.2	1.0	1.8	0.5	0.2	1.1	1.1	1.0	-2.3	-1.5	-1.1
Trunk fat-free mass	0.4	2.0	6.5	-0.3	-0.2	-0.5	-2.0	-0.8	-0.7	-0.8	-2.2	-1.7	-2.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	3.8	1.3	1.4	0.5	-0.5	0.7	0.6	1.9	-1.8	-0.9	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.1	1.0	0.4	0.9	0.4	0.7	0.6	0.9	0.1	0.7	0.7
Asthma	0.4	0.8	2.2	0.1	-1.1	-0.6	-0.4	-0.6	-0.8	-1.3	1.5	1.0	0.3
Trunk predicted mass	0.4	2.1	6.5	-0.3	-0.2	-0.6	-2.0	-0.8	-0.8	-0.8	-2.2	-1.7	-2.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.3	1.5	0.1	-0.9	-0.7	-0.5	-0.7	-0.0	0.2	-0.6	-0.2
Eye problems/disorders: None of the above	0.4	0.4	0.8	-0.6	-0.9	0.1	0.7	0.5	0.5	-0.7	0.7	0.9	0.7
Medication for pain relief, constipation, heartburn	0.4	0.7	2.4	-1.6	-0.8	-0.8	-0.5	-0.8	-0.8	-0.6	0.9	0.4	-0.1
Chest pain or discomfort	0.4	0.6	2.0	0.4	-0.7	0.3	0.7	-0.1	-0.0	-0.7	1.4	0.9	1.2
Long-standing illness, disability or infirmity	0.4	0.6	1.8	-0.0	-1.0	-0.1	-0.0	-0.6	-0.6	-1.0	1.4	1.0	0.8
Arm fat mass (left)	0.4	1.6	5.0	1.1	1.6	0.7	0.1	1.2	1.2	1.2	-2.2	-1.3	-1.0
Medication: Lisinopril	0.4	0.6	2.0	-1.4	-0.8	-0.5	-0.2	-0.8	-0.7	-0.6	0.8	0.6	-0.5
Basal metabolic rate	0.4	2.3	8.6	0.5	1.0	-0.1	-1.4	0.1	0.1	0.2	-2.9	-2.1	-2.5
Unable to work because of sickness or disability	0.4	0.6	1.7	-0.2	-0.8	0.4	0.6	0.3	0.3	-0.7	1.2	1.3	0.9
Pain experienced in last month	0.4	0.6	1.5	-1.2	-1.0	-0.8	-0.2	-0.7	-0.8	-1.1	0.7	0.2	-0.3
Crohns Disease (2017)	0.3	0.7	1.8	1.3	1.0	0.7	0.6	0.7	0.6	1.0	-0.8	-0.7	0.1
Breast Cancer	0.3	0.7	1.8	-0.9	-0.2	-1.2	-0.8	-1.3	-1.1	-0.0	-0.2	-0.6	-0.9
HDL Cholesterol	0.3	0.5	1.4	-0.8	-0.0	-0.6	-0.9	-0.4	-0.4	-0.2	-0.8	-0.6	-1.2
Blood Red Count	0.3	2.8	8.1	0.1	2.0	-0.8	-1.6	-0.4	-0.5	1.5	-2.8	-2.1	-2.3
Chronotype (morning person)	0.3	0.6	2.0	-0.6	-0.9	-0.3	0.2	-0.5	-0.5	-0.5	1.4	1.2	0.7
Number of treatments/medications taken	0.3	0.6	1.8	1.3	-0.3	0.6	0.9	0.5	0.5	0.1	0.8	0.6	1.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.9	1.7	0.2	-0.1	-0.2	-0.3	-0.4	0.3	0.2	-0.3	0.7
Angina	0.3	0.3	1.1	-1.1	-0.9	-0.1	0.4	-0.2	-0.0	-0.9	0.4	0.5	0.3
Trunk fat percentage	0.3	1.1	4.1	0.5	1.3	0.1	-0.0	0.8	0.8	1.0	-2.0	-1.1	-1.2
Hand grip strength (right)	0.3	0.9	2.2	-0.8	-0.2	-1.2	-1.2	-0.9	-0.9	-0.9	-0.5	-0.4	-1.5
Relative age voice broke	0.3	0.4	1.1	-0.8	-1.0	-0.7	-0.4	-0.5	-0.7	-0.2	0.8	0.5	0.5
Hearing difficulty/problems with background noise	0.3	0.4	1.2	0.3	-0.4	0.7	0.7	0.3	0.4	-0.1	1.0	0.8	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.3	0.5	1.1	1.0	0.9	1.1	1.1	0.6	-0.6	-0.5	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.9	-0.7	-0.9	0.1	0.2	-0.5	-0.5	-0.3	1.4	1.2	0.6
Illnesses of mother	0.3	0.4	1.1	0.6	0.1	-0.6	-1.0	-0.5	-0.5	-0.1	-0.7	-0.6	-0.7
Breastfed as a baby	0.3	0.4	1.1	1.1	0.1	0.5	0.3	0.3	0.1	0.4	0.9	0.8	1.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.6	-1.3	-0.8	0.1	0.2	-0.4	-0.3	-0.8	0.7	0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.2	-1.5	-0.8	0.1	-0.1	-0.5	-0.3	-0.2	1.2	1.1	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.7	0.6	0.4	0.8	0.4	0.7	0.6	0.6	0.5	0.3	0.7
Shortness of breath walking on level ground	0.3	0.3	0.7	0.0	-0.4	-0.4	-0.8	-0.7	-0.7	-0.8	-0.3	-0.5	-0.7
Medication: Allopurinol	0.3	0.5	1.6	0.7	-0.3	0.5	1.0	0.7	0.6	0.1	0.5	0.3	1.2
Whole body fat mass	0.3	1.3	5.1	0.8	1.3	0.4	-0.2	0.9	0.9	1.0	-2.2	-1.2	-1.3
Leg fat mass (right)	0.3	1.1	4.7	0.6	1.1	0.0	-0.6	0.7	0.6	0.6	-2.2	-1.2	-1.4
Medication: Aspirin	0.3	0.4	1.1	-0.0	-0.9	-0.5	-0.2	-0.5	-0.6	-0.8	1.0	1.0	0.5
Whole body fat-free mass	0.3	1.9	7.0	0.5	0.7	0.0	-1.4	-0.0	0.0	0.1	-2.6	-1.9	-2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.1	0.9	0.3	-0.0	-0.5	-0.2	-0.2	-0.1	-1.0	-1.1	-0.7
Asthma (self-reported)	0.3	0.6	2.1	0.3	-0.9	-0.3	-0.3	-0.3	-0.5	-1.0	1.5	1.1	0.5
Osteoporosis (self-reported)	0.3	0.3	1.1	0.2	-1.0	0.3	0.3	-0.5	-0.4	-0.7	0.8	0.7	0.3
Medication: Aspirin	0.3	0.3	1.2	0.1	-0.7	-0.3	0.1	-0.2	-0.3	-0.5	1.0	1.1	0.6
Whole body water mass	0.3	1.8	6.5	0.4	0.6	-0.1	-1.5	-0.1	-0.1	-0.1	-2.5	-1.9	-2.3
Ever taken oral contraceptive pill	0.3	0.3	0.7	0.1	-0.4	-0.8	-0.8	-0.7	-0.7	-0.4	-0.3	-0.3	-0.3
Medication: Bendroflumethiazide	0.3	0.5	1.4	1.2	0.6	0.4	0.1	0.5	0.4	1.1	-0.9	-0.2	-0.6
Average weekly beer plus cider intake	0.3	0.4	1.1	0.2	0.9	-0.0	-0.3	0.0	0.0	0.0	-0.8	-1.0	-1.0
Age started oral contraceptive pill	0.3	0.4	1.1	0.5	0.1	-0.7	-0.9	-0.5	-0.6	-0.3	-0.8	-0.5	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	0.3	-0.0	0.6	0.8	0.6	0.7	0.7	0.5	0.7	1.0
Alcohol drinker status: Previous	0.3	0.4	1.5	-0.4	-0.5	0.3	0.5	0.2	0.2	0.3	1.0	1.2	0.8
Bipolar Disorder or Schizophrenia	0.2	0.5	1.3	0.8	0.8	0.9	0.3	0.7	0.0	1.1	0.2	0.6	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.7	-0.8	-0.6	-0.6	-0.6	-0.8	-0.8	-0.3	-0.0	-0.1	-0.5
Reaction Time	0.2	0.4	1.3	0.3	0.8	-0.1	-0.4	0.1	0.0	0.3	-1.0	-1.1	-1.0
Bipolar Disorder (2011)	0.2	0.2	0.7	0.5	0.2	0.0	-0.9	-0.3	0.0	0.0	-0.5	-0.6	-0.2
Systolic Blood Pressure	0.2	1.0	3.0	1.0	-0.3	-1.6	-1.7	-1.0	-1.4	0.0	-0.1	-0.1	-0.8
Hypothyroidism (self reported)	0.2	0.4	1.5	-1.2	-0.6	0.3	0.3	-0.3	-0.0	-0.2	0.9	0.8	0.6
Lung FEV1/FVC ratio	0.2	0.8	2.5	-0.8	-0.1	-0.8	-1.6	-1.0	-1.0	0.6	-1.2	-0.6	-0.7
Hearing difficulty/problems: Yes	0.2	0.4	1.4	-1.0	-1.2	-0.0	-0.2	-0.3	-0.3	-0.7	0.5	0.5	0.3
Relative age of first facial hair	0.2	0.5	1.5	-0.3	-0.2	-1.2	-0.9	-0.8	-1.0	-0.4	-0.0	-0.8	-0.1
Supplements: Glucosamine	0.2	0.3	0.8	-0.0	-0.9	0.2	0.2	-0.2	-0.2	-0.8	0.8	0.6	0.2
Medication: Levothyroxine sodium	0.2	0.3	0.8	-0.1	0.8	0.7	0.6	0.3	0.5	0.9	0.1	0.4	0.3
High blood pressure (mother)	0.2	0.3	0.8	-0.0	0.7	0.1	0.2	0.2	0.3	0.9	-0.7	-0.8	-0.4
Hair/balding pattern: Pattern 2	0.2	0.3	1.3	0.4	0.4	-0.6	-0.1	0.1	-0.1	0.6	0.7	0.6	1.1
Forced vital capacity (FVC)	0.2	0.8	2.3	1.1	1.0	0.4	-0.6	0.6	0.4	1.5	-1.4	-0.6	-0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.1	0.1	0.1	0.3	0.6	0.3	0.4	0.3	0.6	0.3	1.0
Heart attack	0.2	0.3	0.7	0.7	-0.1	-0.4	-0.6	-0.4	-0.6	-0.7	-0.1	-0.8	-0.2
Medication: Ramipril	0.2	0.3	0.8	-0.9	-0.9	-0.1	-0.0	-0.3	-0.2	-0.7	0.5	0.6	0.1
Medication: Simvastatin	0.2	0.3	1.0	-0.6	-0.9	-0.2	0.0	-0.5	-0.3	-1.0	-0.2	0.0	-0.6
Impedance of arm (right)	0.2	0.9	1.7	-1.2	-1.2	-1.3	-0.7	-1.2	-1.2	-0.7	0.6	0.2	-0.4
Tense / ‘highly strung’	0.2	0.4	1.0	-0.6	-0.5	-0.2	-0.6	-0.8	-0.7	-1.0	-0.2	-0.3	-0.8
Hair/balding pattern: Pattern 4	0.2	0.6	1.5	-1.2	-0.9	-0.3	-0.0	-0.6	-0.4	-1.1	0.8	0.7	-0.5
Birth weight of first child	0.2	0.4	1.1	0.3	0.3	0.6	0.2	0.7	0.7	1.1	0.2	0.9	0.9
Blood clot in the leg (DVT)	0.2	0.3	0.9	0.2	-0.2	0.5	0.7	0.4	0.5	0.5	0.5	0.6	0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.3	0.4	1.1	0.7	0.5	0.6	0.6	0.6	-0.2	-0.1	0.0
Forced vital capacity (FVC), Best measure	0.2	0.8	2.7	1.0	0.8	0.4	-0.4	0.5	0.4	1.0	-1.6	-1.1	-1.0
Body fat percentage	0.2	1.0	3.5	0.5	1.2	0.2	0.0	0.9	0.9	0.9	-1.9	-1.0	-1.0
Arm fat-free mass (right)	0.2	1.2	3.8	0.0	0.2	-0.2	-1.4	-0.3	-0.2	-0.3	-2.0	-1.4	-2.0
Comparative body size at age 10	0.2	0.5	1.1	0.2	-0.9	0.2	0.6	0.4	0.4	0.2	1.0	0.9	1.1
Wheeze or whistling in the chest in last year	0.2	0.4	0.8	0.3	-0.7	-0.6	-0.4	-0.5	-0.6	-0.8	0.9	0.9	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.6	-0.4	-0.7	-0.7	-0.3	-0.4	-0.0	-0.1	0.3	-0.5
Angina (self-reported)	0.2	0.2	0.6	-0.8	-0.7	-0.0	0.5	-0.1	0.1	-0.7	0.3	0.4	0.3
Arm predicted mass (right)	0.2	1.2	4.0	0.1	0.2	-0.2	-1.3	-0.2	-0.1	-0.3	-2.0	-1.3	-2.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	0.2	0.6	-0.0	-0.1	0.3	0.3	0.4	-1.0	-1.0	-0.5
Supplements: Vitamin C	0.2	0.3	0.8	-0.0	0.1	0.3	0.6	0.1	0.3	-0.9	-0.6	-0.9	-0.7
Average weekly red wine intake	0.2	0.3	1.8	1.3	0.3	0.4	-0.1	0.3	0.1	0.4	-0.3	-0.2	0.6
Commuting to job workplace: Walk	0.2	0.2	0.9	0.9	0.5	-0.1	0.0	0.2	-0.0	0.0	0.5	0.4	0.7
Back pain experienced in last month	0.2	0.2	1.0	0.1	0.7	0.2	-0.2	0.2	0.3	0.5	-1.0	-0.5	-0.3
Financial situation satisfaction	0.2	0.2	0.5	0.7	0.3	0.5	0.4	0.5	0.5	0.3	-0.2	-0.3	0.6
High cholesterol (Self-reported)	0.2	0.3	0.7	-0.7	-0.0	0.6	0.8	0.5	0.7	-0.4	-0.6	-0.3	-0.3
Leg fat percentage (left)	0.2	0.7	2.8	0.2	1.1	-0.0	-0.1	0.6	0.7	0.5	-1.7	-0.9	-1.1
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.2	-0.3	-0.5	-0.3	-0.5	-0.4	-0.4	0.2	-0.1	-0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	0.1	0.3	0.4	0.4	0.2	0.2	-0.5	-0.3	0.0	0.1
Blood Eosinophil Count	0.1	0.4	1.7	0.2	0.8	0.1	-0.5	0.2	0.2	0.2	-1.3	-0.8	-1.0
Heel T-Score	0.1	0.6	3.0	-0.1	-0.0	0.3	0.4	0.2	-0.1	0.3	1.7	0.6	1.5
Height	0.1	2.7	8.9	-1.3	-1.5	-1.0	-1.9	-0.9	-0.7	-1.3	-2.3	-1.2	-3.0
Hair Pigment	0.1	2.9	6.2	-1.4	-0.1	-2.1	-1.9	-1.5	-1.3	-0.7	-2.1	-2.5	-2.1
Tanning	0.1	1.2	4.4	2.1	1.4	0.6	0.5	1.2	1.0	1.5	-0.5	0.2	0.2
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.2	-0.4	-0.3	-0.4	-0.4	-0.3	-0.2	-0.4	-0.1	-0.2
Age when periods started (menarche)	0.1	0.2	0.6	-0.1	-0.3	-0.0	0.1	-0.4	-0.4	0.3	0.8	0.4	0.8
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.9	-0.2	-0.1	-0.1	0.0	-0.4	-0.2	-0.0	-0.4	-1.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.1	0.2	0.6	-0.2	-0.1	0.1	0.0	0.1	-0.8	-1.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	0.1	0.8	-0.0	-0.4	0.1	-0.0	0.5	-0.4	-0.1	-0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.3	0.0	-0.1	-0.1	0.2	-0.2	-0.1	-0.2	0.5	0.1	0.5
High blood pressure	0.1	0.2	0.6	0.4	-0.1	-0.5	-0.8	-0.4	-0.5	0.0	-0.5	-0.1	-0.5
Sitting height	0.1	0.6	2.2	0.6	0.4	0.3	-1.0	0.2	0.1	0.8	-1.5	-0.7	-1.1
Chronic bronchitis/emphysema (father)	0.1	0.1	0.6	0.5	-0.0	-0.0	-0.5	-0.1	-0.2	0.1	0.3	0.8	0.3
Alcohol usually taken with meals	0.1	0.2	0.8	-0.9	-0.3	0.4	0.4	-0.0	0.3	-0.2	-0.3	-0.3	0.1
Happiness	0.1	0.1	0.3	0.2	0.1	0.4	0.3	0.3	0.6	0.1	-0.4	-0.5	-0.0
Medication: Cholesterol lowering	0.1	0.2	0.3	-0.0	-0.4	0.5	0.5	0.2	0.3	-0.4	0.2	0.6	0.5
Impedance of arm (left)	0.1	0.5	1.2	-0.9	-1.1	-0.8	-0.1	-0.6	-0.7	0.0	1.0	0.8	0.4
Length of working week for main job	0.1	0.1	0.7	-0.8	-0.1	-0.1	-0.5	-0.3	-0.4	-0.3	0.1	-0.2	-0.3
Loud music exposure frequency	0.1	0.1	0.2	-0.0	0.2	-0.4	-0.3	-0.4	-0.5	-0.3	0.2	-0.4	-0.4
Birth weight	0.1	0.3	0.9	-0.1	-0.7	-0.6	-1.0	-0.6	-0.6	-0.3	0.3	0.1	-0.2
Leg fat percentage (right)	0.1	0.5	1.4	-0.6	0.0	-0.8	-0.7	-0.2	-0.1	-0.4	-1.0	-0.6	-1.2
Neck or shoulder pain in last month	0.1	0.1	0.5	-0.1	-0.1	-0.3	-0.0	-0.2	0.0	0.0	-0.6	-0.7	0.1
Pulse rate, automated reading	0.1	0.2	0.5	-0.5	-0.1	-0.5	-0.7	-0.4	-0.6	0.7	0.3	0.5	-0.0
Alcohol intake frequency.	0.1	0.2	0.6	-0.2	0.3	0.5	0.6	0.3	0.4	0.8	-0.2	0.1	0.0
Ever had bowel cancer screening	0.1	0.1	0.3	0.2	-0.4	-0.1	-0.4	-0.4	-0.5	0.0	0.4	0.3	0.5
Commuting to job workplace: Public transport	0.1	0.1	0.3	-0.1	-0.5	-0.5	-0.6	-0.2	-0.3	-0.1	-0.0	0.0	0.1
Medication: Blood pressure	0.1	0.1	0.4	-0.1	0.2	0.1	-0.0	-0.2	-0.0	-0.2	-0.6	-0.4	-0.6
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.9	-0.5	0.1	0.6	1.0	0.5	0.6	0.1	0.6	0.3	0.6
Cholesterol lowering medication	0.1	0.1	0.4	-0.4	0.2	0.3	0.6	0.2	0.4	-0.0	-0.3	-0.3	-0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.6	0.5	-0.3	-0.1	-0.3	-0.3	-0.5	-0.8	0.3	-0.5	0.1
Alzheimer’s Disease (in mother)	0.0	0.0	0.1	0.0	-0.3	0.3	0.0	-0.2	-0.2	-0.0	0.1	0.2	0.2
Blood White Count	0.0	0.2	1.0	1.0	0.7	-0.0	-0.1	0.2	0.1	-0.1	0.0	-0.2	-0.2
Illnesses of siblings	0.0	0.0	0.2	0.2	0.2	0.1	-0.0	-0.0	-0.0	0.1	-0.3	-0.2	-0.5
Falls in the last year	0.0	0.1	0.2	-0.4	-0.1	-0.3	0.0	-0.2	-0.1	-0.3	-0.0	0.0	-0.3
Number of live births	0.0	0.1	0.3	0.1	-0.0	0.3	0.0	0.0	0.1	-0.3	-0.6	-0.1	-0.4
Hypertension (Self-reported)	0.0	0.1	0.8	0.9	-0.1	0.0	-0.2	0.0	-0.0	0.4	-0.2	0.4	0.2

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