Best TWAS P=0 · Best GWAS P=0 conditioned to 0
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HERC2 | 0.07 | 0.00 | bslmm | 317 | 0.01 | 6.7e-03 | -103.5 | -29.7 | 2.1e-194 | 0.17 | 0.05 | 0.03 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | NDNL2 | 0.05 | 0.01 | blup | 426 | 0.02 | 6.3e-04 | -2.1 | 6.2 | 6.8e-10 | 0.05 | 0.33 | 0.02 | TRUE |
| 3 | CommonMind | Brain Pre-frontal Cortex | OCA2 | 0.07 | 0.02 | bslmm | 474 | 0.02 | 7.2e-04 | -53.1 | 35.0 | 3.8e-268 | -0.13 | 0.66 | 0.01 | TRUE |
| 4 | GTEx | Cells Transformed fibroblasts | WHAMMP2 | 0.11 | 0.01 | enet | 11 | 0.02 | 2.3e-02 | -3.6 | -7.4 | 1.6e-13 | 0.01 | 0.02 | 0.12 | TRUE |
| 5 | GTEx | Thyroid | HERC2 | 0.11 | 0.01 | lasso | 4 | 0.02 | 8.6e-03 | -14.3 | 20.9 | 3.4e-97 | -0.15 | 0.12 | 0.03 | TRUE |
| 6 | GTEx | Whole Blood | HERC2 | 0.29 | 0.28 | lasso | 4 | 0.28 | 9.2e-26 | -98.1 | -99.5 | 0.0e+00 | 0.49 | 1.00 | 0.00 | FALSE |
| 7 | METSIM | Adipose | GOLGA8M | 0.12 | 0.00 | lasso | 5 | 0.04 | 3.0e-06 | -6.5 | 5.2 | 1.9e-07 | -0.03 | 0.22 | 0.15 | TRUE |
| 8 | NTR | Blood | APBA2 | 0.02 | 0.01 | blup | 374 | 0.01 | 1.8e-04 | -8.0 | -7.9 | 2.8e-15 | 0.12 | 0.67 | 0.04 | TRUE |
| 9 | YFS | Blood | HERC2 | 0.10 | 0.10 | bslmm | 279 | 0.10 | 1.1e-30 | -105.1 | -107.0 | 0.0e+00 | 0.53 | 1.00 | 0.00 | TRUE |
| 10 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | OCA2 | 0.28 | 0.12 | lasso | 5 | 0.09 | 4.4e-05 | -23.7 | -22.1 | 1.5e-108 | -0.03 | 0.70 | 0.02 | TRUE |
| 11 | The Cancer Genome Atlas | Stomach Adenocarcinoma | APBA2 | 0.17 | 0.05 | lasso | 1 | 0.04 | 8.2e-04 | 6.9 | 6.9 | 5.4e-12 | -0.06 | 0.47 | 0.02 | TRUE |