[Hub]/) : Traits : Hair Pigment :

chr17:37,584,368-39,221,312

Best TWAS P=1.42e-10 · Best GWAS P=2.2e-23 conditioned to 2.71e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MSL1 0.15 0.12 lasso 2 0.12 3.9e-10 6.4 -6.4 1.7e-10 -0.05 0.01 0.99 FALSE
2 GTEx Artery Tibial MSL1 0.19 0.14 lasso 2 0.15 4.9e-12 6.4 -5.5 3.5e-08 -0.07 0.01 0.99 FALSE
3 GTEx Breast Mammary Tissue MSL1 0.20 0.06 lasso 6 0.07 2.2e-04 6.4 -5.4 5.9e-08 -0.05 0.01 0.98 FALSE
4 GTEx Colon Transverse MSL1 0.18 0.11 lasso 3 0.05 2.1e-03 6.4 -6.1 1.0e-09 -0.06 0.01 0.96 FALSE
5 GTEx Esophagus Muscularis MSL1 0.25 0.18 lasso 8 0.22 1.7e-13 6.5 -6.1 1.0e-09 -0.07 0.00 1.00 FALSE
6 GTEx Nerve Tibial MSL1 0.33 0.25 lasso 4 0.24 6.3e-17 6.4 -6.1 1.2e-09 -0.07 0.01 0.99 FALSE
7 GTEx Pituitary MSL1 0.40 0.27 lasso 7 0.24 1.3e-06 4.9 -6.0 2.2e-09 -0.09 0.05 0.80 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic MSL1 0.18 0.15 lasso 4 0.15 2.1e-08 6.4 -6.4 1.4e-10 -0.04 0.01 0.99 TRUE
9 METSIM Adipose MSL1 0.12 0.06 lasso 10 0.06 1.8e-09 6.4 -5.5 4.4e-08 -0.07 0.01 0.99 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma KRT12 0.17 0.06 lasso 2 0.06 2.7e-04 -6.2 -6.2 5.0e-10 0.55 0.00 0.96 TRUE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RAPGEFL1 0.13 0.02 enet 9 0.06 4.3e-04 6.5 -5.3 1.2e-07 -0.08 0.00 0.93 FALSE