Best TWAS P=1.23e-07 · Best GWAS P=1.57e-07 conditioned to 0.0559
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | TRIM47 | 0.42 | 0.07 | lasso | 4 | 0.06 | 0.0040 | -5.1 | -5.2 | 1.9e-07 | -0.06 | 0.01 | 0.78 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRB2 | 0.02 | 0.00 | blup | 43 | 0.01 | 0.0046 | -5.2 | -5.3 | 1.2e-07 | 0.88 | 0.01 | 0.82 | TRUE |