Best TWAS P=6.46e-10 · Best GWAS P=5.91e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | SLC44A2 | 0.19 | 0.18 | lasso | 5 | 0.19 | 5.1e-18 | -5.6 | -5.8 | 7.2e-09 | 0.78 | 0.26 | 0.74 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SMARCA4 | 0.15 | 0.10 | enet | 25 | 0.15 | 1.4e-12 | -3.7 | 6.0 | 1.7e-09 | -0.62 | 0.98 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC147727 | 0.07 | 0.02 | lasso | 2 | 0.02 | 5.4e-03 | -6.0 | 6.2 | 6.5e-10 | -0.98 | 0.01 | 0.85 | TRUE |