[Hub]/) : Traits : Hair Pigment :

chr5:32,740,984-34,706,321

Best TWAS P=1.77e-54 · Best GWAS P=0 conditioned to 0

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADAMTS12 0.09 0.00 bslmm 529 0.01 1.0e-02 1.71 -9.5 1.5e-21 0.11 0.08 0.05 FALSE
2 CommonMind Brain Pre-frontal Cortex RXFP3 0.12 0.08 enet 21 0.08 1.3e-09 1.19 -7.3 2.4e-13 0.11 1.00 0.00 TRUE
3 GTEx Artery Aorta AMACR 0.34 0.21 enet 19 0.28 8.4e-16 3.28 -5.9 3.0e-09 -0.14 1.00 0.00 FALSE
4 GTEx Artery Coronary AMACR 0.46 0.20 lasso 6 0.27 1.7e-09 3.28 -5.2 1.7e-07 -0.15 0.98 0.00 FALSE
5 GTEx Brain Frontal Cortex BA9 AMACR 0.72 0.43 enet 14 0.39 1.6e-11 2.98 -5.5 3.3e-08 -0.14 0.99 0.00 FALSE
6 GTEx Cells EBV-transformed lymphocytes AMACR 0.45 0.15 lasso 10 0.17 3.9e-06 3.28 -12.8 2.8e-37 0.01 0.32 0.03 FALSE
7 YFS Blood TARS 0.03 0.00 bslmm 456 0.01 1.0e-03 0.10 -7.4 1.3e-13 0.14 0.09 0.02 TRUE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AMACR 0.05 0.01 enet 10 0.02 1.1e-03 -0.15 5.7 1.6e-08 -0.23 0.06 0.03 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma AMACR 0.42 0.42 enet 14 0.45 1.0e-56 2.98 -7.0 2.0e-12 -0.13 1.00 0.00 TRUE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AMACR 0.23 0.26 blup 72 0.25 1.0e-16 5.24 5.2 2.0e-07 -0.30 1.00 0.00 TRUE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma AMACR 0.31 0.23 enet 9 0.29 1.4e-12 2.98 8.4 3.1e-17 -0.31 1.00 0.00 TRUE
12 The Cancer Genome Atlas Stomach Adenocarcinoma AMACR 0.09 0.03 blup 78 0.06 1.9e-05 5.58 -15.5 1.8e-54 0.02 0.29 0.02 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma ADAMTS12 0.09 0.08 enet 11 0.08 3.1e-08 1.64 5.8 9.1e-09 -0.06 0.98 0.01 TRUE