Best TWAS P=1.85e-12 · Best GWAS P=6.28e-34 conditioned to 2.46e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PKHD1 | 0.07 | 0.00 | blup | 252 | 0.03 | 2.4e-04 | 5.7 | -6.5 | 8.3e-11 | 0.31 | 0.09 | 0.05 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | PKHD1 | 0.03 | 0.03 | lasso | 5 | 0.02 | 9.5e-04 | 7.1 | 6.6 | 3.5e-11 | -0.18 | 0.50 | 0.01 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PKHD1 | 0.04 | 0.05 | lasso | 3 | 0.05 | 1.7e-06 | 5.4 | -7.0 | 1.8e-12 | 0.49 | 0.92 | 0.06 | TRUE |