Best TWAS P=3.78e-23 · Best GWAS P=2.97e-30 conditioned to 4.25e-11
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | RMND1 | 0.30 | 0.16 | enet | 14 | 0.10 | 5.0e-04 | -4.7 | 5.4 | 8.4e-08 | 0.15 | 0.22 | 0.04 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | AKAP12 | 0.11 | 0.02 | blup | 140 | 0.04 | 5.3e-05 | -7.9 | 9.9 | 3.8e-23 | 0.64 | 0.02 | 0.88 | TRUE |