Best TWAS P=2.83e-18 · Best GWAS P=9.9e-22 conditioned to 3.86e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CDKN2B | 0.08 | 0.05 | lasso | 4 | 0.06 | 2.4e-07 | -8.4 | -8.7 | 2.8e-18 | 0.75 | 0.18 | 0.82 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | CDKN2B-AS1 | 0.11 | 0.02 | blup | 501 | 0.03 | 1.7e-04 | -8.4 | -5.5 | 3.6e-08 | 0.68 | 0.06 | 0.93 | FALSE |