Best TWAS P=1.16e-10 · Best GWAS P=4.97e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | STX17 | 0.07 | 0.05 | lasso | 3 | 0.05 | 2.9e-04 | -5.4 | -5.3 | 1.1e-07 | 0.72 | 0.40 | 0.42 | FALSE |
| 2 | GTEx | Lung | STX17 | 0.08 | 0.07 | lasso | 7 | 0.10 | 2.8e-08 | -5.3 | -5.6 | 2.7e-08 | 0.84 | 0.04 | 0.96 | FALSE |
| 3 | GTEx | Thyroid | STX17 | 0.09 | 0.01 | lasso | 4 | 0.04 | 7.0e-04 | -5.4 | -5.2 | 2.5e-07 | 0.51 | 0.06 | 0.59 | FALSE |
| 4 | NTR | Blood | STX17 | 0.03 | 0.02 | lasso | 2 | 0.02 | 1.9e-07 | -6.6 | 6.5 | 1.2e-10 | -1.00 | 0.01 | 0.99 | TRUE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | STX17 | 0.11 | 0.07 | blup | 54 | 0.10 | 7.4e-05 | -6.2 | -6.2 | 6.6e-10 | 0.92 | 0.03 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | STX17 | 0.13 | -0.01 | blup | 57 | 0.05 | 2.0e-02 | -5.4 | -5.6 | 2.0e-08 | 0.82 | 0.02 | 0.40 | FALSE |