[Hub]/) : Traits : Hair Pigment :

chr9:128,980,174-130,673,419

Best TWAS P=7.98e-11 · Best GWAS P=1.92e-10 conditioned to 0.267

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RALGPS1 0.08 0.07 enet 27 0.09 3.8e-11 5.1 6.5 8.0e-11 0.91 0.04 0.96 TRUE
2 GTEx Brain Cerebellum RALGPS1 0.28 0.17 lasso 7 0.19 2.8e-06 6.0 6.3 3.4e-10 0.99 0.04 0.96 FALSE
3 GTEx Esophagus Mucosa RALGPS1 0.05 0.01 lasso 6 0.02 2.7e-02 -5.5 -6.3 3.7e-10 -0.69 0.18 0.56 FALSE
4 GTEx Skin Sun Exposed Lower leg RALGPS1 0.06 0.02 lasso 6 0.01 2.5e-02 -5.5 -6.5 8.0e-11 -0.81 0.09 0.88 FALSE
5 GTEx Testis RALGPS1 0.23 0.32 lasso 9 0.29 2.7e-13 -6.1 -6.3 2.7e-10 -0.93 0.04 0.96 FALSE
6 GTEx Whole Blood RALGPS1 0.10 0.10 enet 10 0.08 1.2e-07 6.1 -5.9 3.2e-09 -0.99 0.04 0.96 FALSE
7 METSIM Adipose RALGPS1 0.04 0.04 lasso 3 0.04 2.8e-06 -5.5 -5.9 3.0e-09 -0.63 0.55 0.45 FALSE
8 YFS Blood RALGPS1 0.08 0.13 lasso 18 0.15 1.1e-45 -5.6 -6.5 9.1e-11 -0.82 0.54 0.46 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ANGPTL2 0.02 0.01 lasso 2 0.01 6.2e-02 6.2 -5.8 6.0e-09 -0.98 0.02 0.75 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ANGPTL2 0.10 0.08 blup 38 0.09 2.8e-04 6.4 6.0 1.9e-09 0.93 0.02 0.93 FALSE