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chr10:73,158,678-75,079,280

Best TWAS P=7.19e-10 · Best GWAS P=1.21e-11 conditioned to 0.00462

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MICU1	0.04	0.06	lasso	5	0.07	4.6e-09	5.4	-5.2	2.1e-07	-0.78	0.98	0.02	FALSE
2	GTEx	Adipose Subcutaneous	MICU1	0.06	0.05	lasso	6	0.05	3.7e-05	5.8	6.2	7.2e-10	0.92	0.23	0.76	TRUE
3	GTEx	Adipose Subcutaneous	DNAJB12	0.06	0.06	lasso	3	0.06	1.6e-05	5.2	5.6	2.3e-08	0.89	0.40	0.59	FALSE
4	GTEx	Artery Tibial	MICU1	0.03	0.06	lasso	4	0.04	8.0e-04	5.2	5.1	2.7e-07	0.87	0.38	0.57	FALSE
5	GTEx	Cells Transformed fibroblasts	MICU1	0.08	0.07	lasso	4	0.06	3.9e-05	5.5	5.8	7.9e-09	0.81	0.44	0.47	FALSE
6	GTEx	Cells Transformed fibroblasts	DNAJB12	0.22	0.17	lasso	6	0.16	6.5e-12	5.2	5.2	1.9e-07	0.89	0.91	0.09	FALSE
7	GTEx	Esophagus Muscularis	DNAJB12	0.07	0.07	lasso	3	0.06	2.6e-04	5.2	5.2	2.4e-07	0.86	0.18	0.68	FALSE
8	GTEx	Pancreas	DNAJB12	0.08	0.00	lasso	4	0.02	4.7e-02	5.5	5.5	3.0e-08	0.80	0.15	0.33	FALSE
9	GTEx	Skin Sun Exposed Lower leg	MICU1	0.02	0.02	lasso	4	0.01	9.3e-02	5.5	5.9	3.3e-09	0.86	0.19	0.48	FALSE
10	GTEx	Skin Sun Exposed Lower leg	DNAJB12	0.14	0.08	lasso	3	0.06	6.8e-06	5.8	5.6	2.3e-08	0.92	0.37	0.61	FALSE
11	GTEx	Spleen	DNAJB12	0.12	0.08	lasso	5	0.06	1.1e-02	5.8	6.0	2.1e-09	0.92	0.07	0.76	FALSE
12	GTEx	Stomach	ASCC1	0.20	0.02	lasso	5	0.02	3.1e-02	5.6	5.5	4.7e-08	0.68	0.21	0.19	FALSE
13	GTEx	Thyroid	DNAJB12	0.22	0.20	lasso	9	0.21	7.6e-16	5.2	5.5	2.9e-08	0.90	0.80	0.20	FALSE
14	METSIM	Adipose	DNAJB12	0.15	0.04	bslmm	379	0.08	2.2e-12	-2.2	5.7	1.2e-08	0.70	0.05	0.95	FALSE
15	YFS	Blood	DNAJB12	0.08	0.05	enet	21	0.05	2.0e-15	5.9	5.6	1.7e-08	0.79	0.09	0.91	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	ASCC1	0.02	0.01	lasso	3	0.01	2.0e-02	5.9	6.0	2.6e-09	0.85	0.00	0.91	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAJB12	0.02	0.03	lasso	1	0.02	6.3e-03	5.7	5.7	1.1e-08	0.84	0.04	0.70	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJB12	0.04	0.03	enet	5	0.03	1.6e-04	5.8	5.2	2.0e-07	0.88	0.05	0.91	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DNAJB12	0.03	0.04	blup	36	0.05	4.8e-04	5.8	5.7	1.6e-08	0.89	0.03	0.81	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	CBARA1	0.03	0.02	blup	111	0.03	5.5e-04	5.3	5.3	9.7e-08	0.78	0.18	0.67	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	DNAJB12	0.10	0.09	lasso	5	0.10	1.4e-09	5.8	5.6	1.9e-08	0.91	0.32	0.68	FALSE