[Hub]/) : Traits : Hair Pigment :

chr11:6,755,218-8,375,907

Best TWAS P=1.41e-57 · Best GWAS P=2.98e-61 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPFIBP2 0.10 0.07 lasso 5 0.06 1.9e-07 -16.5 -16.0 1.4e-57 0.95 0.00 1.00 TRUE
2 GTEx Artery Aorta CTD-2516F10.2 0.31 0.30 lasso 3 0.30 4.6e-17 -13.9 -14.6 3.1e-48 0.79 0.94 0.06 TRUE
3 GTEx Artery Tibial CTD-2516F10.2 0.40 0.32 enet 28 0.34 2.4e-27 -13.9 -13.1 3.5e-39 0.71 1.00 0.00 FALSE
4 GTEx Cells Transformed fibroblasts CTD-2516F10.2 0.52 0.33 lasso 10 0.36 8.6e-28 -13.9 -13.7 5.6e-43 0.74 1.00 0.00 FALSE
5 GTEx Nerve Tibial PPFIBP2 0.17 0.00 enet 27 0.02 1.0e-02 3.3 -7.3 3.3e-13 0.41 0.02 0.72 FALSE
6 GTEx Nerve Tibial CTD-2516F10.2 0.26 0.13 enet 21 0.14 6.8e-10 -13.1 -11.0 4.3e-28 0.66 0.69 0.31 FALSE
7 GTEx Skin Sun Exposed Lower leg CTD-2516F10.2 0.12 0.07 lasso 3 0.11 3.4e-09 -13.9 -11.5 7.6e-31 0.70 0.40 0.58 FALSE
8 GTEx Thyroid CTD-2516F10.2 0.22 0.10 lasso 4 0.16 2.9e-12 -13.9 -12.1 1.0e-33 0.70 0.98 0.02 FALSE
9 GTEx Whole Blood CTD-2516F10.2 0.29 0.09 enet 49 0.09 2.7e-08 -13.9 -10.2 1.5e-24 0.50 0.24 0.76 FALSE
10 NTR Blood PPFIBP2 0.06 0.01 lasso 10 0.03 1.6e-10 -2.7 9.0 2.2e-19 -0.41 0.99 0.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex PPFIBP2 0.10 0.01 bslmm 723 0.05 3.2e-07 -16.5 -9.5 2.6e-21 0.41 0.00 0.99 FALSE
12 YFS Blood PPFIBP2 0.67 0.27 enet 135 0.51 2.6e-197 -11.6 5.4 6.5e-08 -0.33 1.00 0.00 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma OLFML1 0.20 0.03 blup 95 0.07 1.0e-04 2.9 11.1 1.0e-28 -0.54 0.00 0.83 FALSE