Hub : Genes

PPFIBP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0980 0.0290 3.5e-04 0.065 0.020 0.056 0.053 0.056 2.1e-08 1.6e-03 2.0e-07 4.3e-07 1.9e-07
2 GTEx Brain Cerebellum 0.3510 0.1140 4.7e-03 -0.006 NA -0.007 NA 0.003 5.1e-01 NA 5.9e-01 NA 2.6e-01
3 GTEx Nerve Tibial 0.1739 0.0522 1.6e-03 -0.004 NA 0.022 NA -0.004 9.4e-01 NA 1.0e-02 NA 7.7e-01
4 METSIM Adipose 0.0541 0.0238 7.9e-03 -0.002 0.006 0.018 0.005 0.000 8.4e-01 4.3e-02 7.6e-04 5.1e-02 3.5e-01
5 NTR Blood 0.0634 0.0149 4.5e-08 0.012 0.027 0.031 0.031 0.032 6.7e-05 3.1e-09 2.8e-10 3.2e-10 1.6e-10
6 ROSMAP Brain Pre-frontal Cortex 0.0999 0.0302 3.3e-04 0.015 0.048 0.019 0.051 0.038 4.7e-03 7.7e-07 1.4e-03 3.2e-07 1.0e-05
7 YFS Blood 0.6682 0.0258 0.0e+00 0.270 0.418 0.509 0.303 0.353 1.7e-88 2.1e-150 2.6e-197 2.5e-101 1.3e-121
8 TCGA Thyroid Carcinoma 0.1420 0.0430 2.7e-05 0.066 0.062 0.085 NA 0.105 4.8e-07 1.1e-06 1.2e-08 NA 2.4e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.7 2.5 -1.0 0.9 -0.3 -0.6 1.6 -0.3 0.9 -0.1
Bipolar Disorder or Schizophrenia 0.2 0.5 1.3 -0.5 -0.5 -0.8 -0.9 0.6 -1.2 -0.6 -0.1
Depressed Affect (Nagel 2018) 0.7 1.4 4.1 -1.3 -1.5 -0.4 0.5 1.0 -1.2 -0.5 2.0
Depression (Nagel 2018) 0.7 1.0 3.3 0.8 -0.3 -0.9 1.8 0.3 -1.8 0.2 0.2
Intelligence (Savage-Jansen 2018) 0.3 1.0 3.2 0.4 0.6 1.5 0.2 -1.1 1.8 0.3 -0.9
Neuroticism (Nagel 2018) 0.3 0.6 2.0 0.5 -1.4 0.5 0.8 0.2 0.0 -0.8 1.1
Schizophrenia (2018) 0.4 0.8 1.9 0.2 -1.3 -0.9 -0.7 -0.4 -1.2 -1.4 -0.0
Schizophrenia vs Biploar Disorder 1.4 1.8 3.8 1.2 0.5 1.8 -1.6 -1.5 0.3 -1.9 -1.1
Worry (Nagel 2018) 0.6 1.3 4.5 2.1 0.1 1.5 -0.4 -0.6 1.1 -1.3 0.2
Alzheimer’s Disease (in mother) 0.3 0.4 1.0 -0.5 0.9 -0.4 -0.6 0.4 -0.6 0.3 1.0
Alzheimer’s Disease (in father) 0.6 0.6 1.7 -0.7 0.2 0.8 1.3 -0.1 0.1 1.3 -0.5
Alzheimer’s Disease (including proxy) 0.1 0.1 0.6 0.1 -0.0 0.5 0.1 -0.4 -0.1 0.8 0.3
Crohns Disease (2017) 0.5 1.0 3.0 -0.1 0.7 1.7 -1.0 -0.5 0.9 -0.2 1.7
Irritable Bowel Disease (IBD) 0.8 1.8 4.8 0.3 2.2 1.7 -1.5 -0.5 0.7 -1.0 1.6
Ulcerative Colitis (UC) 0.7 1.3 3.9 0.3 2.0 1.1 -1.2 -0.4 0.5 -1.1 1.4
Major Depression (MDD) 0.4 0.5 1.8 -0.1 -0.3 1.3 -0.7 0.3 -0.5 -0.5 0.8
Reaction Time 0.9 1.7 9.8 1.0 0.7 -0.9 -0.1 -1.0 -0.8 0.3 -3.1
Verbal and Numeric Reasoning (VNR) 0.5 1.1 5.5 0.3 1.0 0.9 -0.2 -0.8 2.4 -0.0 -0.9
Breast Cancer 0.9 2.1 5.7 -2.3 0.1 -1.9 0.8 0.8 -2.4 1.0 0.4
Ovarian Cancer 0.3 0.5 1.7 0.3 -0.1 -0.1 -1.2 0.2 1.3 -0.5 0.4
Prostate Cancer 0.6 0.9 2.8 -0.2 -0.3 0.4 -1.7 -1.3 -0.0 -0.5 1.3
Age at First Birth 1.0 1.4 4.1 0.7 -0.1 1.0 -2.0 -1.1 1.6 -1.4 0.6
Bipolar Disorder (2011) 0.3 0.3 1.5 0.1 0.0 -0.3 -1.2 -0.3 -0.4 -0.8 0.0
Body Mass Index (BMI) (2010) 0.9 1.2 3.3 0.6 -1.5 -1.0 0.0 -0.8 -1.8 -1.3 0.8
Coronary Artery Disease (CAD) 1.7 2.1 10.1 -0.8 1.0 -0.3 0.2 1.0 -1.9 0.3 3.2
Crohns Disease (2012) 0.5 0.7 4.4 -2.1 0.6 0.7 -0.1 0.3 0.4 -0.2 0.5
Mean Putamen Volume 0.9 1.0 2.8 -1.3 -0.6 0.0 -1.7 -1.0 -1.2 -0.6 -0.5
Fasting Glucose 0.5 0.5 1.1 1.0 1.0 0.8 -0.4 -0.9 0.4 -0.4 -0.5
HbA1C 0.6 0.7 2.3 1.5 1.1 0.6 0.2 1.1 0.7 -0.0 0.1
HDL Cholesterol 0.4 0.7 3.6 -0.6 0.6 0.1 0.3 0.9 -0.0 -0.4 1.9
LDL Cholesterol 0.2 0.3 1.3 -0.6 -1.1 0.6 0.0 0.2 0.2 0.1 -0.1
Lupus 0.6 0.9 4.0 -0.8 -0.2 1.0 -0.4 1.1 -0.3 0.3 2.0
Neuroticism (2016) 0.2 0.2 0.7 -0.5 -0.4 0.4 0.9 0.2 -0.2 -0.7 0.1
Primary Biliary Cirrhosis 0.7 1.0 2.4 0.1 -0.2 -0.9 1.6 -0.6 1.5 0.7 -1.1
Rheumatoid Arthritis 0.2 0.3 0.7 0.3 0.4 0.4 0.7 -0.5 -0.2 -0.8 0.5
Schizophrenia (2014) 0.1 0.2 1.4 0.1 -0.4 -0.3 -0.2 0.2 -0.1 -1.2 -0.1
Triglycerides 0.3 0.5 1.7 0.8 -0.7 0.7 0.2 0.4 0.7 0.2 1.3
Type 2 Diabetes (T2D) (2012) 1.1 1.2 4.1 2.0 -0.4 0.7 -0.7 1.1 0.5 0.4 1.7
Ulcerative Colitis 0.7 1.1 6.3 -0.5 2.5 0.4 -0.4 0.3 0.4 -1.1 0.4
Blood Eosinophil Count 0.1 0.8 3.3 1.8 -1.2 0.5 0.4 -0.4 0.0 -0.8 0.6
Blood Platelet Count 0.2 2.0 5.4 0.5 1.6 1.6 0.6 1.5 2.3 1.5 0.2
Blood Red Count 0.3 3.3 10.6 0.1 2.1 3.2 -1.1 -0.7 2.9 -0.1 -1.1
Blood White Count 0.1 0.7 1.7 0.1 0.7 1.1 -1.2 0.3 0.5 -0.4 -1.3
Heel T-Score 0.2 1.5 3.8 -0.6 1.1 0.4 -1.5 -1.7 -0.3 -1.1 -1.9
BMI 0.2 1.0 5.3 -0.4 0.4 1.0 2.3 0.3 -0.0 0.6 -1.0
Height 0.2 3.5 8.3 -0.1 -2.3 -1.0 1.9 2.6 -1.4 2.9 -1.0
Waist Hip Ratio (WHR) 0.3 1.4 3.8 -1.5 2.0 0.6 0.9 -0.9 0.6 0.3 -1.5
Systolic Blood Pressure 0.3 1.6 3.8 0.5 1.6 -1.7 2.0 0.3 -0.1 -1.4 1.0
Smoking Status 0.2 0.6 1.6 -0.9 -0.0 -0.1 -0.6 -0.6 -1.0 -1.3 -0.8
Allergy or Eczema 0.6 1.5 5.3 0.6 -2.3 0.8 0.4 0.7 1.7 1.0 1.1
Cardiovascular Disease 0.5 1.5 2.8 1.6 1.5 0.2 1.2 -1.5 0.9 -1.7 -0.2
Hypothyroidism (self reported) 0.2 0.4 1.0 0.6 -1.0 0.2 0.1 0.0 -0.9 -0.2 1.0
Respiratory disease 0.4 1.0 2.7 0.2 -1.6 0.7 -0.4 0.2 1.5 1.3 -0.6
Type 2 Diabetes (T2D) (2018) 0.4 0.7 2.8 1.0 -0.1 -0.6 -0.2 1.0 -0.6 1.7 -0.5
Lung FEV1/FVC ratio 0.1 0.6 2.7 -0.5 -0.6 0.4 0.7 0.7 -1.6 -0.4 -0.2
Lung FVC 0.2 1.2 3.7 1.4 0.5 1.9 -0.3 -0.6 1.5 -0.0 -1.1
Neuroticism 0.6 1.3 4.9 0.1 -1.0 2.2 0.1 0.2 0.1 -1.0 2.0
Chronotype (morning person) 0.3 0.7 1.8 0.5 0.8 -0.4 1.0 0.0 -1.3 0.9 1.0
Hair Pigment 2.4 69.5 256.0 -16.0 -1.8 -7.3 4.4 9.0 -9.5 5.4 4.9
Tanning 0.1 0.9 3.2 1.8 -1.7 -0.3 0.2 -0.7 0.8 -0.4 -0.1
Hand grip strength (left) 0.2 0.6 2.7 1.1 -1.6 0.2 -0.4 0.4 -0.3 -0.0 0.6
Number of treatments/medications taken 1.5 2.7 6.6 0.3 1.8 1.4 1.6 2.0 0.6 2.6 -1.7
Average weekly spirits intake 0.9 1.1 3.0 -0.6 1.0 0.5 0.8 1.6 1.1 1.7 0.1
Sensitivity / hurt feelings 0.5 0.8 1.8 -1.2 0.1 1.3 0.7 0.9 0.1 1.1 0.8
Frequency of depressed mood in last 2 weeks 1.1 1.5 5.3 0.3 -1.1 -0.9 1.9 -0.3 -2.3 -0.4 0.8
Hearing difficulty/problems: Yes 0.8 1.2 3.6 1.1 0.0 1.9 1.0 -0.7 1.3 -0.7 -0.9
Relative age of first facial hair 0.3 0.6 1.7 -0.1 -0.5 0.4 -1.3 -1.2 -0.5 -0.7 0.8
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.0 0.2 -0.3 -1.0 0.5 0.2 0.2 -0.9 -0.9
Ever used hormone-replacement therapy (HRT) 0.8 1.0 3.3 0.7 0.4 -0.0 -1.7 -0.9 -0.3 0.2 -1.8
Ever had hysterectomy (womb removed) 0.7 0.8 2.0 -1.4 0.8 0.3 -1.0 -0.9 -1.1 -0.7 -0.4
Systolic blood pressure, automated reading 0.2 0.6 1.6 0.7 1.2 -0.3 0.2 -0.9 -0.3 -1.3 0.2
Eye problems/disorders: Diabetes related eye disease 4.3 4.7 7.2 -2.6 -0.9 -2.5 1.8 2.4 -2.7 2.3 -1.6
Angina 1.7 2.2 5.8 -1.4 1.1 -0.6 1.8 1.5 -0.4 2.4 -1.7
Medication for hormone replacement therapy 1.3 1.4 6.2 -0.6 1.4 0.6 0.2 0.4 0.9 1.3 -2.5
Vitamin and mineral supplements 0.3 0.4 1.1 -0.7 0.3 -0.6 1.1 -0.5 0.4 -0.0 0.6
Supplements: Zinc 1.1 1.2 3.5 -0.7 0.6 0.2 1.1 1.9 -0.9 1.5 -1.0
Medication: Co-codamol 0.4 0.5 1.9 0.7 0.3 0.5 -1.4 -0.3 0.2 -1.0 0.3
Medication: Metformin 1.0 1.4 3.3 -0.2 0.5 -0.9 1.5 1.4 -1.8 1.2 -1.0
Diabetes (father) 1.9 2.3 7.7 1.7 -0.5 1.0 -0.7 -2.1 0.6 -2.8 1.1
Diabetes (mother) 0.2 0.3 0.9 0.1 -0.2 -0.2 -0.9 -0.3 -0.6 -0.0 0.9
Severe depression (siblings) 2.6 2.9 6.9 1.2 -2.0 1.4 -2.6 -2.1 0.9 -1.6 1.1
Pack years adult smoking proportion 0.1 0.1 0.4 -0.2 0.1 0.2 -0.1 -0.2 -0.5 -0.3 -0.6
Impedance of leg (right) 0.2 1.0 4.2 -0.8 -0.5 -2.1 0.5 -0.2 -1.4 0.7 0.6
Leg fat-free mass (left) 0.1 0.6 1.1 0.5 -0.9 1.0 1.0 0.9 0.3 0.7 -0.2
Trunk fat percentage 0.2 0.8 2.8 -1.1 0.4 -0.2 1.7 0.2 -0.8 -0.1 -1.1
Hand grip strength (right) 0.4 1.0 4.9 1.4 -2.2 0.1 -0.7 0.2 0.5 -0.5 0.6
Townsend deprivation index at recruitment 1.4 2.0 5.8 -2.4 1.4 -1.1 0.8 0.6 -2.4 -0.1 -0.3
Current tobacco smoking 0.7 1.1 2.9 -1.5 0.1 -1.2 0.3 -0.4 -1.7 -0.3 -1.4
Average weekly fortified wine intake 1.4 1.6 4.9 1.0 -1.2 1.1 -0.8 0.3 2.2 -0.2 1.9
Maternal smoking around birth 0.8 1.2 4.6 -0.4 2.1 0.8 1.1 1.3 -0.9 0.1 0.7
Fed-up feelings 1.2 2.2 4.0 -2.0 -1.9 -0.3 0.5 1.7 -1.6 -0.1 2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.9 2.5 10.4 -0.7 0.2 -1.3 3.2 1.0 -2.5 0.7 0.5
Relative age voice broke 0.8 1.2 4.6 -0.5 -0.8 -0.4 -1.5 -1.4 -0.2 -2.1 0.2
Taking other prescription medications 0.2 0.4 1.7 0.5 1.3 0.1 -0.2 -0.1 -0.3 -0.5 -0.7
Age when periods started (menarche) 0.8 2.0 5.1 -0.0 -0.1 -1.8 2.2 1.2 -1.3 0.6 2.0
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 3.7 -0.0 1.2 0.5 0.6 -1.0 -0.2 0.4 -1.9
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 8.2 0.1 0.5 -0.6 -0.8 -0.7 0.7 -2.9 -0.9
Tinnitus: Yes, but not now, but have in the past 1.1 1.1 3.6 -1.9 -0.6 -1.2 0.4 -0.4 -1.8 -0.1 0.4
Qualifications: CSEs or equivalent 1.3 1.8 5.4 -0.9 0.6 1.3 1.7 1.0 1.4 0.4 2.3
Serious illness, injury or assault to yourself 1.3 1.6 3.1 -1.0 1.4 -1.2 -0.6 -1.3 -1.7 -1.7 -0.6
High blood pressure 0.5 1.5 5.1 1.4 2.2 0.8 0.2 -1.3 0.7 -1.4 0.5
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.7 -0.5 -1.7 0.1 0.5 0.7 1.2 0.7 0.8
Multivitamins +/- minerals 0.5 0.6 1.4 1.2 -1.0 0.6 -1.1 0.6 -0.5 -0.6 0.1
Stomach or abdominal pain in last month 0.4 0.6 1.3 -0.2 0.3 -1.0 1.1 -0.3 -0.9 0.1 -1.1
Supplements: Glucosamine 0.7 0.9 4.2 0.4 -0.1 -0.7 -0.6 -0.8 -0.8 -0.8 -2.1
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.8 0.5 0.3 -0.1 0.2 -0.4 -0.9 -0.4 0.1
Medication: Atenolol 1.3 1.6 5.1 -0.4 1.3 -0.4 0.2 0.8 -1.4 2.3 -1.6
Medication: Levothyroxine sodium 0.2 0.4 0.9 -0.8 -0.7 -0.1 0.7 -0.4 -1.0 -0.3 -0.4
Sitting height 0.3 2.2 5.6 1.0 -2.4 -1.8 1.3 1.0 1.3 1.5 -1.0
Chronic bronchitis/emphysema (father) 1.0 1.1 3.3 0.7 1.1 1.8 -0.8 -1.2 0.3 -1.4 -0.2
High blood pressure (mother) 0.9 1.2 4.2 1.5 0.9 1.1 -0.4 -2.0 0.9 -0.5 -0.2
Body mass index (BMI) 0.2 0.7 2.5 -0.5 0.9 1.3 1.6 0.4 -0.1 -0.0 -0.5
Impedance of leg (left) 0.3 1.3 6.9 -0.6 -0.4 -2.6 0.6 -0.1 -1.3 0.6 -0.4
Leg predicted mass (left) 0.1 0.5 1.1 0.5 -0.9 1.1 0.9 0.8 0.2 0.6 -0.2
Trunk fat mass 0.1 0.4 2.2 -0.5 -0.1 0.3 1.5 0.1 -0.5 0.0 -0.8
Waist circumference 0.4 1.5 3.5 -1.1 1.8 1.5 1.9 0.0 0.2 0.8 -1.2
Number of incorrect matches in round 0.5 0.8 3.6 -1.4 0.1 0.4 1.9 0.1 0.7 -0.2 0.2
Past tobacco smoking 0.3 0.5 2.4 0.6 0.1 -0.0 0.8 -0.1 1.6 0.3 0.4
Alcohol usually taken with meals 0.8 1.3 3.5 0.4 -1.1 0.5 -1.4 -0.3 1.7 -0.1 -1.9
Nervous feelings 2.4 4.4 9.1 3.0 -1.2 2.0 -1.2 -2.3 2.2 -3.0 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 7.5 0.5 0.4 -0.2 2.7 0.7 -0.9 0.3 0.5
Hearing difficulty/problems with background noise 0.3 0.5 2.1 -0.3 -0.7 -0.4 0.6 -0.6 0.3 0.0 -1.5
Hair/balding pattern: Pattern 2 1.1 1.4 7.7 -1.1 -0.3 -0.7 2.8 1.2 0.2 0.5 0.4
Had menopause 0.8 1.0 3.4 0.2 1.4 -0.5 -0.3 -0.8 -0.6 -1.1 -1.8
Had other major operations 0.6 0.7 4.2 -0.3 0.1 -0.1 0.0 0.4 0.3 0.9 -2.0
Forced vital capacity (FVC) 0.2 0.8 1.5 1.2 -0.9 0.5 0.2 0.9 1.0 1.0 -1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 5.2 -0.3 1.1 -0.1 -0.1 -0.1 0.2 -2.3 0.4
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 2.7 -0.6 -0.1 -1.6 0.9 0.6 -1.3 1.1 -0.1
Qualifications: None of the above 0.8 1.6 5.9 -1.5 2.4 -0.0 0.9 0.7 -1.8 0.2 0.7
Financial difficulties in last 2 years 0.4 0.5 1.6 0.3 -1.2 -0.7 0.6 0.7 0.3 1.1 0.2
Mouth/teeth dental problems 0.5 0.7 2.2 0.4 0.3 0.2 -1.5 -1.2 0.3 -1.3 -0.5
Heart attack 1.3 1.6 5.0 -1.1 -0.0 -0.7 1.5 1.8 -0.5 2.2 -0.6
Allergy 0.5 1.3 4.2 0.9 2.0 -0.0 -0.0 -0.9 -1.8 -1.0 -0.4
Pain all over the body in last month 0.4 0.5 2.3 -0.2 1.5 0.4 0.2 -0.4 0.7 -0.7 0.3
Diabetes (self-reported) 1.3 2.0 7.3 -0.5 0.6 -0.6 1.1 2.1 -1.6 2.7 -0.3
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.6 0.6 -0.3 0.1 -0.5 -0.1 0.3 -0.4 -0.8
Medication: Ramipril 0.9 1.1 3.8 1.3 1.9 -0.6 1.2 0.1 0.7 0.8 -1.0
Medication: Simvastatin 0.7 1.0 3.9 0.4 1.3 2.0 1.1 0.1 -1.1 -0.1 0.3
Fluid intelligence score 0.2 0.4 1.2 -0.9 0.5 0.6 0.1 -0.0 1.1 0.5 -0.1
Illnesses of siblings 0.3 0.4 1.6 -0.9 -1.3 0.4 -0.7 0.4 0.3 0.3 -0.1
Neuroticism score 0.8 1.6 6.8 0.2 -0.8 2.6 -0.2 0.2 0.9 -0.9 1.8
Weight 0.2 0.9 3.6 -0.0 -0.4 0.8 1.9 0.9 -0.1 1.0 -0.8
Impedance of arm (right) 0.2 0.8 4.8 -0.9 -0.2 -2.2 -0.0 0.3 -0.4 0.2 -0.7
Arm fat percentage (right) 0.2 0.7 2.7 -0.6 0.7 0.8 1.6 0.2 0.2 0.0 -1.3
Trunk fat-free mass 0.2 1.1 2.1 1.1 -1.3 1.3 1.1 1.2 0.1 1.5 -0.2
Hip circumference 0.2 1.0 3.8 0.0 0.4 0.8 2.0 0.7 0.4 1.1 -1.3
Time employed in main current job 0.7 0.8 1.7 -1.3 -0.5 -0.4 0.4 0.6 1.0 1.2 -1.1
Alcohol intake versus 10 years previously 0.4 0.5 1.9 -0.1 0.1 -0.6 1.2 -0.3 -1.4 0.4 -0.4
Father’s age at death 1.1 1.4 6.0 1.9 -0.8 0.8 -0.3 -0.2 2.5 0.1 -0.7
Worrier / anxious feelings 0.6 1.2 5.1 2.3 0.6 1.4 -0.3 0.1 1.1 -0.7 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.4 4.5 0.2 0.5 0.2 2.1 1.8 -0.2 1.5 -1.1
Falls in the last year 0.1 0.2 0.8 -0.2 0.4 0.9 0.2 0.6 0.3 0.0 -0.0
Hair/balding pattern: Pattern 3 0.9 1.4 3.8 0.2 0.9 -0.8 -1.9 -1.2 -0.9 -0.9 -1.6
Number of live births 0.9 1.3 3.8 0.4 1.9 1.5 -0.3 -1.0 0.7 -1.6 0.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 1.3 1.1 -1.0 0.5 -0.1 0.8 0.2 0.5 -0.9
Pulse rate 0.5 0.9 5.2 2.3 -0.0 0.7 0.6 -0.6 0.6 -0.5 0.1
Happiness 0.2 0.2 0.4 -0.3 -0.6 0.4 -0.0 -0.6 -0.4 -0.3 0.4
Noisy workplace 0.5 0.7 2.9 -0.5 -0.7 0.2 1.7 0.8 -0.1 0.9 0.2
Qualifications: A levels/AS levels or equivalent 1.9 4.1 10.3 2.9 -1.3 0.2 -2.2 -2.0 3.2 -2.0 -0.1
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.8 5.5 -0.9 -2.3 -0.6 -0.8 -1.2 0.1 -2.3 0.1
Mouth/teeth dental problems: Dentures 0.3 0.5 1.6 1.1 -0.6 0.4 -0.6 0.7 1.2 0.0 0.3
Asthma 0.6 1.1 2.8 -0.3 -0.7 0.1 0.4 1.7 1.6 1.6 -0.5
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.2 -1.5 0.4 -0.4 1.0 1.0 0.3 1.2 -1.1
Medication: Cholesterol lowering 0.3 0.4 1.0 0.3 0.7 0.8 1.0 0.8 -0.0 0.4 -0.3
Depression (self-reported) 0.3 0.4 1.4 -1.1 -0.3 -0.1 -0.4 -0.3 -0.3 -0.5 1.2
Medication: Lansoprazole 0.6 0.6 2.2 0.1 0.1 -0.2 0.4 0.8 -1.5 1.4 -0.2
Prospective memory result 0.2 0.2 0.6 0.8 -0.7 0.2 0.2 -0.4 -0.6 0.1 -0.2
Lung cancer (father) 1.4 1.6 4.9 -1.6 -0.8 -1.3 -0.2 -0.9 0.1 -1.4 -2.2
Illnesses of mother 0.7 0.9 2.8 -0.4 -1.7 0.1 0.2 0.6 1.5 0.3 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 2.2 1.5 -0.4 0.9 0.2 1.3 1.2 0.6 -1.3
Pulse wave Arterial Stiffness index 1.2 1.4 4.0 -0.2 0.0 1.5 -2.0 -1.2 0.9 -0.6 1.4
Impedance of arm (left) 0.2 1.0 5.6 -1.4 -0.3 -2.4 -0.1 -0.1 -0.5 -0.1 -0.2
Arm fat mass (right) 0.2 0.7 2.7 -0.3 0.4 1.1 1.6 0.4 0.1 0.4 -1.1
Trunk predicted mass 0.2 1.1 2.2 1.0 -1.2 1.2 1.1 1.3 -0.1 1.5 -0.1
Standing height 0.2 2.0 7.6 1.0 -2.8 -1.0 0.8 1.0 0.0 2.1 -0.7
Length of working week for main job 1.2 1.4 5.1 -0.1 -0.0 1.3 -1.5 -0.8 -0.4 -2.3 1.1
Exposure to tobacco smoke at home 1.0 1.1 4.0 -0.5 1.0 0.8 -0.3 -0.0 1.6 -0.1 2.0
Breastfed as a baby 0.4 0.5 0.9 -0.7 0.9 -0.9 0.7 -0.1 -0.7 -0.7 -0.6
Tense / ‘highly strung’ 0.6 1.0 2.0 0.6 -1.1 1.4 -0.6 -0.6 1.0 -1.1 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.8 0.1 -0.7 -0.0 -0.7 -0.8 0.7 -1.4 0.2
Hair/balding pattern: Pattern 4 0.6 1.4 6.1 2.5 -1.2 0.5 -0.2 -0.7 -1.3 -0.8 0.8
Birth weight of first child 0.2 0.3 1.1 0.0 -0.6 1.0 -0.1 -0.6 0.2 -0.2 -0.7
Peak expiratory flow (PEF) 0.3 0.7 2.5 0.1 -1.2 1.6 -0.8 0.2 -0.7 -0.3 -0.1
Pulse wave reflection index 1.6 1.9 7.2 -2.7 -0.6 0.6 -0.6 -0.4 0.1 -0.0 2.6
Ever highly irritable/argumentative for 2 days 1.5 1.8 4.8 1.0 -0.4 0.9 -1.8 -2.2 1.3 -1.7 0.4
Loud music exposure frequency 1.0 1.1 3.4 -1.4 -0.3 -1.9 0.6 -0.7 -0.2 -0.0 -1.5
Qualifications: O levels/GCSEs or equivalent 0.5 0.7 2.2 1.5 0.3 -0.0 0.1 -0.5 1.0 -0.4 -1.4
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 3.1 0.4 -0.6 1.1 1.8 -0.0 0.6 0.0 -0.1
Blood clot in the leg (DVT) 0.9 1.2 4.3 0.8 -2.1 -0.8 0.7 -0.3 -0.7 0.4 -1.6
Medication: Paracetamol 0.2 0.4 1.8 -0.5 0.5 0.3 1.3 0.2 -0.0 0.5 -0.6
Headache pain in last month 0.6 1.0 4.0 0.3 -0.2 0.8 2.0 0.6 1.6 0.4 -0.4
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.7 -0.4 0.2 -0.2 -0.5 -0.7 0.8 -0.4 -0.9
Glaucoma (self-reported) 1.1 1.3 4.1 1.3 -1.1 2.0 0.4 0.3 1.3 1.1 -0.4
Gout (self-reported) 0.6 0.9 4.1 -0.8 -0.3 -2.0 0.7 0.7 -1.0 -0.2 0.2
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.6 -0.1 -0.1 0.6 0.1 -0.2 -0.8 0.2 0.5
Medication: Amlodipine 0.4 0.6 2.1 -0.1 -0.0 -0.9 -0.1 1.5 -0.7 0.9 -0.6
Medication: Ventolin 100micrograms inhaler 0.9 1.2 3.4 -1.0 0.8 -0.1 0.6 1.9 -0.6 1.8 -0.9
Birth weight 0.2 0.5 1.3 0.9 1.0 1.1 0.5 0.4 -0.3 0.7 -0.1
Chronic bronchitis/emphysema (mother) 1.3 1.5 3.3 -0.2 1.4 -1.4 1.7 1.8 -0.6 1.1 0.7
High blood pressure (siblings) 0.2 0.2 0.7 0.4 -0.2 0.2 0.7 -0.4 -0.4 0.8 -0.4
Forced vital capacity (FVC), Best measure 0.3 1.1 3.5 1.4 -0.2 0.9 -0.1 1.2 1.9 0.9 -0.8
Body fat percentage 0.2 0.7 3.2 -1.0 0.6 0.0 1.8 0.0 -0.6 -0.2 -1.0
Leg fat percentage (right) 0.2 0.6 2.7 -0.5 0.7 0.7 1.6 -0.5 -0.5 -0.3 -0.7
Arm fat-free mass (right) 0.1 0.6 1.2 0.6 -1.1 0.6 1.1 1.0 -0.5 0.9 -0.1
Exposure to tobacco smoke outside home 1.9 2.5 6.4 -1.2 1.9 1.1 1.4 2.3 0.2 2.5 0.4
Comparative body size at age 10 1.1 3.1 9.0 1.0 0.0 3.0 -2.3 -2.2 1.2 -1.8 -0.3
Number of full brothers 1.1 1.3 6.3 0.5 2.5 0.3 1.1 -0.7 1.2 0.3 -0.9
Worry too long after embarrassment 0.8 1.3 2.6 1.6 -1.4 1.0 1.0 0.9 1.6 0.4 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.0 -0.7 0.3 -1.0 -0.2 -1.4 -0.6 -1.0 0.1
Wheeze or whistling in the chest in last year 0.8 1.5 3.2 -0.8 0.7 1.8 1.1 1.6 1.3 1.5 0.4
Number of children fathered 0.7 0.8 1.9 -1.0 -1.4 -0.1 -0.1 1.2 0.8 1.3 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 3.3 -0.2 -0.5 0.1 -0.4 -1.8 0.7 -1.0 -0.1
Age at first live birth 0.4 0.7 4.2 -0.2 -2.1 -0.8 0.3 0.1 -0.2 -0.3 0.9
Pulse wave peak to peak time 1.1 1.3 3.5 0.3 -0.2 -1.5 1.9 1.0 -0.9 0.6 -1.4
Health satisfaction 0.4 0.5 2.0 1.4 -1.1 0.1 0.4 -0.8 -0.1 0.0 -0.4
Shortness of breath walking on level ground 0.5 0.6 2.3 0.6 0.8 0.2 -0.2 -0.9 0.5 0.4 -1.5
Qualifications: College or University degree 0.6 1.8 6.8 0.6 -1.1 0.4 -2.6 -1.2 1.8 -1.0 -0.1
Eye problems/disorders: None of the above 0.3 0.3 0.8 0.5 0.9 0.8 0.0 -0.5 -0.6 -0.1 -0.3
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.4 -0.4 0.1 -0.5 1.2 1.6 -0.6 1.0 -0.2
Emphysema/chronic bronchitis 0.9 1.0 2.2 1.0 -1.3 0.9 -0.8 -1.0 1.5 0.7 -0.5
Medication for pain relief, constipation, heartburn 0.6 1.0 2.2 1.0 0.4 0.7 -1.5 -1.3 0.9 -1.2 0.6
Neck or shoulder pain in last month 0.4 0.6 1.8 -0.9 1.1 1.3 -0.4 -0.0 -0.3 0.4 0.7
Medication: Blood pressure 0.1 0.1 0.5 0.2 -0.3 -0.4 -0.1 0.4 -0.7 -0.1 0.1
Angina (self-reported) 1.4 1.9 5.2 -1.3 0.8 -0.5 1.6 1.2 -0.5 2.3 -1.7
Migraine (self-reported) 1.5 1.8 5.7 -1.1 -1.8 -2.4 0.6 -0.7 -0.4 -1.8 -0.7
Medication: Ibuprofen 0.7 0.9 2.6 -1.6 0.3 -0.1 0.7 0.8 1.0 1.2 -0.8
Medication: Allopurinol 0.6 0.7 2.3 -1.0 0.5 -1.1 0.1 0.5 -1.5 -0.7 0.5
Medication: Omeprazole 1.5 1.8 4.9 1.9 -0.1 0.5 -1.1 -1.3 1.7 -2.2 0.5
Medication: Seretide 50 evohaler 2.1 2.4 5.6 0.4 1.2 2.4 -2.2 -1.2 2.2 -1.1 0.1
Mean time to correctly identify matches 1.0 1.9 8.8 0.6 1.0 -0.7 -0.4 -0.8 -1.8 -0.7 -3.0
Heart disease (mother) 0.7 0.9 2.9 0.5 1.0 0.2 1.7 0.7 -0.6 1.5 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.2 8.1 -1.8 -2.8 -1.5 0.7 1.5 -0.8 0.3 0.6
Whole body fat mass 0.1 0.5 2.9 -0.3 0.4 0.7 1.7 0.2 -0.3 0.1 -0.8
Leg fat mass (right) 0.1 0.5 3.0 -0.2 0.2 0.6 1.7 0.0 -0.7 -0.0 -0.7
Arm predicted mass (right) 0.1 0.7 1.4 0.7 -1.2 1.0 1.0 1.0 -0.4 1.0 -0.2
Pulse rate, automated reading 0.8 2.6 7.8 1.7 0.7 -0.2 -0.7 -2.1 -0.8 -2.8 -1.9
Alcohol intake frequency. 0.1 0.3 1.1 0.1 -0.7 0.3 0.6 0.1 0.3 0.2 1.1
Comparative height size at age 10 0.3 1.4 3.6 0.0 -1.5 -0.6 1.7 1.3 0.5 1.9 -0.7
Number of full sisters 0.7 0.9 2.1 -0.4 -1.3 -0.7 0.9 -1.1 -0.5 -0.1 -1.5
Suffer from ‘nerves’ 0.7 1.1 4.6 0.7 2.1 1.2 -0.6 -1.0 0.8 -0.3 -0.8
Overall health rating 1.3 2.9 7.6 -0.2 0.6 0.5 2.6 2.8 -0.6 2.7 -0.6
Chest pain or discomfort 0.6 0.9 3.3 0.7 -1.5 -0.6 1.8 0.5 0.3 0.6 -0.1
Had major operations 0.3 0.4 1.6 -0.7 0.4 -0.0 -0.3 0.6 -1.3 0.4 -0.4
Age at last live birth 0.5 0.7 3.1 -0.5 -1.8 -1.1 -0.2 -0.2 -0.4 -0.7 0.6
Family relationship satisfaction 0.4 0.5 2.1 -0.0 0.0 0.3 0.8 0.9 -0.9 0.0 1.5
Leg pain on walking 0.3 0.4 1.7 -0.5 -1.0 -0.3 0.3 0.3 0.3 1.3 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 3.0 -1.4 0.1 -0.1 1.7 1.1 -0.3 1.4 -0.3
Commuting to job workplace: Car/motor vehicle 1.8 2.0 6.9 0.6 -2.6 -0.3 -0.1 -1.2 -0.2 -1.0 2.5
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 2.1 1.1 1.2 1.4 -0.3 1.4 1.3 1.2 0.6
Medication: Aspirin 1.2 1.6 4.8 -1.0 -0.6 -0.8 1.1 1.5 -2.2 1.4 -0.7
Supplements: Vitamin C 0.3 0.3 0.9 0.7 -0.3 -0.4 -0.6 0.6 -0.3 1.0 -0.1
Knee pain experienced in last month 0.9 1.4 3.5 -1.9 -0.8 1.8 -0.7 -0.5 -1.1 -1.2 0.8
Hypertension (Self-reported) 0.4 1.0 4.3 0.9 2.1 0.3 0.2 -1.2 0.6 -1.1 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.2 4.1 -0.7 2.0 0.8 0.4 1.1 -0.2 1.1 1.4
Illnesses of father: Heart disease 0.5 0.7 1.7 -0.9 -0.2 1.2 1.3 -0.3 0.0 0.7 -1.0
Illnesses of siblings: Diabetes 0.1 0.1 0.4 0.0 0.1 -0.5 0.6 -0.2 0.1 0.6 -0.1
Smoking status: Previous 0.3 0.5 1.2 0.7 0.0 0.9 -1.0 -0.6 -0.3 -1.1 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 6.4 0.2 -2.5 -1.0 0.4 -0.5 0.6 0.3 0.1
Whole body fat-free mass 0.2 0.9 1.4 0.8 -1.1 1.1 1.0 1.1 -0.0 1.2 -0.3
Leg fat-free mass (right) 0.1 0.5 0.8 0.7 -0.9 0.9 0.8 0.7 0.4 0.5 -0.6
Arm fat percentage (left) 0.1 0.5 1.9 -0.9 0.5 0.7 1.4 -0.2 0.1 -0.4 -0.8
Average weekly red wine intake 0.8 1.1 4.2 -1.3 -2.0 -0.4 0.0 0.7 0.4 0.8 -1.2
Handedness (chirality/laterality): Left-handed 0.8 1.0 3.9 1.5 0.3 -0.2 0.8 -0.0 -0.3 2.0 -1.0
Mood swings 0.7 1.3 3.3 -0.9 -1.5 -0.3 0.6 0.7 -1.5 -1.1 1.8
Loneliness, isolation 0.5 0.8 3.0 0.9 -0.6 1.1 0.1 -0.6 -0.2 -0.6 1.7
Long-standing illness, disability or infirmity 0.9 1.4 4.5 0.0 -0.1 -1.1 1.5 0.9 0.2 1.4 -2.1
Ever had bowel cancer screening 0.6 0.7 2.5 -0.5 0.3 0.7 -0.5 1.6 -0.7 1.3 0.3
Diabetes diagnosed by doctor 1.0 1.6 3.8 -0.7 0.1 -0.7 1.0 1.7 -1.9 1.9 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 5.3 -0.6 -2.3 -1.6 0.6 -0.1 -2.0 -0.5 0.8
Friendships satisfaction 0.2 0.3 1.0 -0.2 0.2 -0.2 -1.0 -0.2 -0.4 -0.6 -0.7
Qualifications: nursing, teaching 1.3 2.0 6.3 1.5 0.3 1.5 -1.6 -0.6 2.5 -1.4 -0.4
Commuting to job workplace: Walk 0.7 0.7 2.5 0.5 1.6 -0.2 0.2 -0.3 -1.3 -0.4 -1.0
Eye problems/disorders: Cataract 1.3 1.5 2.7 -1.7 -1.0 -1.5 0.3 1.5 0.6 -0.7 1.5
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 3.8 -2.0 -0.5 -0.7 1.0 1.1 -1.6 1.3 0.1
Medication for cholesterol 1.3 2.0 7.8 -1.3 -2.8 -1.8 -1.1 -0.2 -0.7 -1.1 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 1.9 0.3 -0.7 -0.7 -0.8 0.2 -1.3 -1.4 1.1
Back pain experienced in last month 0.6 0.9 2.8 -0.5 -0.5 1.4 -0.0 -0.7 -1.7 -0.0 1.1
Mineral and other dietary supplements 0.5 0.7 1.5 -1.2 -0.1 -1.1 0.8 0.6 -0.2 -0.3 1.2
Breast cancer (self-reported) 0.5 0.5 0.9 -0.8 0.6 0.5 -1.0 -0.8 -0.7 0.6 -0.7
Asthma (self-reported) 0.5 1.1 2.7 -0.8 -0.8 -0.0 0.5 1.6 1.4 1.6 -0.4
Osteoporosis (self-reported) 0.8 1.0 3.0 -0.8 -0.0 -0.6 1.0 1.0 -0.9 1.7 -1.2
Osteoarthritis (self-reported) 1.6 2.0 6.3 0.2 1.9 2.5 1.1 0.4 1.1 1.2 1.4
Medication: Aspirin 1.2 1.6 4.1 -1.1 -0.1 -0.6 1.3 2.0 -1.8 1.5 -0.3
Medication: Gliclazide 0.4 0.4 0.9 0.9 0.4 1.0 0.6 -0.4 0.6 0.4 -0.6
Illnesses of father: None of the above (group 1) 1.2 1.5 8.0 -1.2 -1.2 -2.8 0.5 0.1 -0.7 0.7 -0.1
Smoking status: Current 0.8 1.3 3.3 -1.6 -0.0 -1.4 0.4 -0.2 -1.8 -0.0 -1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.4 0.1 1.8 0.9 0.9 0.6 1.2 0.0 -0.8
Whole body water mass 0.2 0.9 1.6 0.7 -1.1 1.1 1.0 1.2 -0.0 1.2 -0.3
Leg predicted mass (right) 0.1 0.4 0.7 0.7 -0.8 0.8 0.7 0.7 0.4 0.4 -0.6
Arm fat mass (left) 0.1 0.5 2.1 -0.4 0.2 1.0 1.5 0.4 0.0 0.2 -0.8
Number of self-reported non-cancer illnesses 0.3 0.5 1.6 0.1 1.3 0.9 0.8 -0.3 0.4 -0.3 0.9
Average weekly champagne plus white wine intake 0.6 0.8 2.8 -1.7 1.1 -0.4 0.1 0.5 -0.8 0.2 1.1
Miserableness 0.9 1.6 3.6 -1.6 -1.9 -0.4 1.7 1.5 0.0 0.7 0.7
Guilty feelings 1.6 2.5 6.5 0.5 -0.8 2.6 -0.5 -1.7 0.7 -1.8 2.3
Wears glasses or contact lenses 1.5 1.8 3.9 0.3 0.2 0.9 -1.7 -2.0 0.3 -1.9 -1.6
Ever taken oral contraceptive pill 0.4 0.4 1.3 0.9 0.1 -0.3 0.3 0.7 0.4 0.4 -1.1
Hearing aid user 0.7 0.8 1.8 -1.0 1.3 -0.3 -0.6 -1.0 -1.2 -1.0 -0.3
Mother’s age at death 1.0 1.3 2.2 1.1 0.9 -0.1 -1.5 -1.4 -1.1 -1.2 1.2
Financial situation satisfaction 0.2 0.2 1.0 0.1 -0.5 0.3 1.0 0.2 0.5 0.0 -0.5
Tinnitus: Yes, now most or all of the time 1.2 1.4 4.4 1.1 0.3 1.3 -1.3 -0.9 0.8 -2.1 1.0
Commuting to job workplace: Public transport 1.4 1.7 3.4 -1.5 1.8 1.2 -0.6 0.3 1.3 1.2 -1.7
Eye problems/disorders: Glaucoma 0.8 1.0 2.4 1.1 -0.5 1.6 0.2 0.1 1.1 1.1 -1.2
Medication: Blood pressure 0.6 1.2 5.6 0.7 2.4 1.0 1.1 0.4 -0.2 1.1 0.2
Pain type(s) experienced in last month: Hip pain 0.9 1.2 4.1 -0.1 -0.8 0.2 0.6 2.0 -0.4 1.9 -0.7
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.7 0.8 0.6 0.3 -0.5 -0.2 -0.7 0.2 -0.6
High cholesterol (Self-reported) 1.6 2.9 10.4 1.2 3.2 2.9 -0.3 -1.5 -0.4 -0.4 0.6
Medication: Bendroflumethiazide 0.4 0.6 1.1 0.1 0.7 -1.0 0.7 -0.7 -0.7 -0.8 -1.0
Medication: Paracetamol 0.2 0.3 1.2 -0.3 0.1 0.6 1.1 -0.5 0.5 0.0 -0.2
Medication: Lisinopril 2.2 2.9 6.5 -1.0 -2.1 -1.9 2.6 1.1 -1.0 1.7 -1.7
Medication: Atorvastatin 0.6 0.7 4.0 -0.5 2.0 0.5 -0.5 -0.5 -0.3 0.7 -0.1
Illnesses of father: High blood pressure 0.8 1.0 3.4 1.3 0.6 0.1 -1.8 -0.5 0.8 -1.0 -0.5
Alcohol drinker status: Never 0.7 0.8 2.9 0.7 -0.5 1.3 -0.8 -0.7 1.7 -0.3 0.3
Ever smoked 0.4 0.7 2.3 -1.5 -0.4 -0.0 -0.8 0.1 -1.4 -0.2 -0.7
Basal metabolic rate 0.2 0.9 1.7 0.6 -1.0 1.2 1.3 1.2 0.0 1.3 -0.3
Leg fat percentage (left) 0.2 0.8 3.1 -0.4 0.8 0.3 1.8 -0.5 -0.4 -0.3 -1.4
Arm fat-free mass (left) 0.2 1.0 2.1 0.9 -0.8 1.0 1.4 1.1 0.0 1.3 -0.5
Number of operations (self-reported) 0.9 1.4 5.2 -2.3 0.5 -0.5 0.6 1.3 -1.4 0.9 -0.9
Average weekly beer plus cider intake 0.4 0.6 1.8 -0.7 0.1 0.3 1.3 0.7 1.3 -0.5 -0.2
Irritability 0.8 1.4 5.3 -0.4 -0.6 2.3 -0.2 1.2 -0.2 -0.8 1.7
Risk taking 0.2 0.3 0.9 -1.0 -0.4 -0.6 0.7 0.4 -0.2 -0.1 -0.5
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.5 0.2 -0.3 -0.4 0.4 0.3 -0.2 1.2 -1.2
Fractured/broken bones in last 5 years 0.8 1.0 5.3 2.3 0.7 0.0 -0.4 -0.9 0.4 -0.8 -0.9
Age started oral contraceptive pill 0.5 0.6 1.9 1.2 -0.6 0.1 -0.8 -0.3 0.7 0.4 -1.4
Diastolic blood pressure, automated reading 0.4 1.2 4.6 0.3 2.1 -0.2 -0.4 -0.9 -0.6 -1.8 0.7
Ever depressed for a whole week 0.4 0.5 2.5 0.2 -0.4 0.4 -0.1 0.2 -1.6 0.9 -0.8
Unable to work because of sickness or disability 1.2 1.6 5.5 -0.6 0.8 -1.4 1.7 2.4 -0.2 1.0 0.2
Commuting to job workplace: Cycle 1.4 1.7 6.7 -1.0 -1.2 -1.2 -1.1 1.1 -2.6 0.6 0.8
Myopia 1.1 1.6 4.8 0.4 -2.2 1.6 -0.3 0.2 1.5 -0.3 1.7
Vascular/heart problems diagnosed by doctor 0.4 1.2 4.0 -1.3 -2.0 -0.6 -0.7 1.3 -0.6 0.9 0.2
Cholesterol lowering medication 1.1 1.6 7.7 0.8 1.8 2.8 0.8 -0.4 -0.5 0.1 0.5
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 5.2 1.7 -0.6 0.6 -1.6 -1.5 2.0 -2.3 0.9
Pain experienced in last month 0.4 0.7 2.8 1.1 0.5 -0.2 -1.7 -0.7 0.7 -0.5 -0.4
Supplements: Calcium 0.9 1.0 2.6 0.7 0.1 0.9 -1.4 -1.3 0.8 -0.5 -1.6
Basal cell carcinoma (self-reported) 1.1 1.3 3.0 -1.4 0.2 -1.6 -0.9 0.2 -1.7 -1.3 -0.4
Heart attack/myocardial infarction (self-reported) 1.5 1.9 5.8 -1.1 0.1 -0.6 1.8 2.0 -0.1 2.4 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 4.5 0.9 -2.1 -0.9 0.4 -0.4 -0.4 0.1 -1.5
Heart disease (siblings) 0.5 0.6 3.3 0.6 0.9 0.4 1.8 0.2 0.1 -0.1 0.7
Alcohol drinker status: Previous 0.9 1.0 4.2 -0.9 2.1 -0.8 0.1 0.6 -0.7 0.1 1.2
Pack years of smoking 0.1 0.2 0.8 -0.0 0.5 0.2 -0.3 -0.3 -0.4 -0.4 -0.9
Impedance of whole body 0.3 1.3 7.7 -1.1 -0.5 -2.8 0.2 -0.1 -1.0 0.3 -0.3
Leg fat mass (left) 0.2 0.6 3.2 -0.1 0.3 0.4 1.8 -0.0 -0.6 -0.1 -1.0
Arm predicted mass (left) 0.2 1.0 1.9 0.6 -0.9 1.1 1.4 1.2 -0.4 1.3 -0.5