Best TWAS P=1.55e-13 · Best GWAS P=7.65e-13 conditioned to 0.157
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | 6.8 | 6.8 | 1.1e-11 | 0.83 | 0.04 | 0.79 | FALSE |
2 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | 6.8 | -6.8 | 9.1e-12 | -0.86 | 0.04 | 0.89 | FALSE |
3 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | 6.8 | -6.4 | 2.0e-10 | -0.84 | 0.04 | 0.96 | FALSE |
4 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | 6.8 | -7.4 | 1.5e-13 | -0.88 | 0.04 | 0.96 | TRUE |