Best TWAS P=1.17e-21 · Best GWAS P=6.77e-25 conditioned to 9.96e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | 6.4 | 7.2 | 5.5e-13 | 0.67 | 0.95 | 0.05 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 9.7 | 9.5 | 3.3e-21 | 0.94 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 9.7 | 9.6 | 1.2e-21 | 0.95 | 0.05 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 2.7e-04 | 9.8 | 8.1 | 6.3e-16 | 0.83 | 0.05 | 0.78 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM2 | 0.05 | 0.00 | blup | 339 | 0.02 | 3.2e-03 | 5.5 | 6.1 | 1.3e-09 | 0.66 | 0.05 | 0.46 | FALSE |