Best TWAS P=9.02e-10 · Best GWAS P=3.99e-10 conditioned to 0.0119
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | DCBLD2 | 0.29 | 0.27 | enet | 28 | 0.26 | 8.4e-21 | -4.9 | 5.1 | 2.9e-07 | 0.67 | 0.81 | 0.19 | FALSE |
| 2 | GTEx | Artery Tibial | ST3GAL6 | 0.14 | 0.09 | enet | 21 | 0.16 | 3.4e-12 | 4.8 | -5.4 | 5.5e-08 | -0.59 | 0.82 | 0.18 | FALSE |
| 3 | GTEx | Nerve Tibial | ST3GAL6 | 0.17 | 0.15 | enet | 30 | 0.23 | 3.3e-16 | 4.8 | -5.5 | 3.1e-08 | -0.75 | 0.14 | 0.86 | FALSE |
| 4 | GTEx | Pituitary | ST3GAL6-AS1 | 0.20 | 0.10 | lasso | 3 | 0.21 | 5.5e-06 | -3.5 | 6.1 | 9.0e-10 | 0.75 | 0.02 | 0.91 | TRUE |
| 5 | GTEx | Skin Sun Exposed Lower leg | DCBLD2 | 0.17 | 0.12 | lasso | 7 | 0.15 | 9.2e-13 | 4.8 | 5.2 | 1.6e-07 | 0.82 | 0.19 | 0.81 | FALSE |
| 6 | YFS | Blood | ST3GAL6 | 0.08 | 0.10 | lasso | 8 | 0.10 | 2.1e-32 | 5.8 | 5.7 | 9.3e-09 | 0.84 | 0.03 | 0.97 | FALSE |