Best TWAS P=2.66e-08 · Best GWAS P=1.45e-06 conditioned to 0.219
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | CYSTM1 | 0.22 | 0.15 | lasso | 11 | 0.12 | 0.00034 | 4.8 | -5.2 | 2.5e-07 | -0.98 | 0.02 | 0.82 | FALSE |
2 | GTEx | Brain Putamen basal ganglia | LINC01024 | 0.22 | 0.03 | lasso | 6 | 0.04 | 0.03630 | 4.8 | -5.6 | 2.7e-08 | -0.94 | 0.02 | 0.56 | TRUE |