[Hub]/) : Traits : Tanning :

chr5:176,040,488-177,260,129

Best TWAS P=7.93e-11 · Best GWAS P=4.15e-10 conditioned to 0.719

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MXD3 0.33 0.06 lasso 6 0.05 9.1e-04 -5.9 -6.0 2.6e-09 0.89 0.00 0.99 FALSE
2 GTEx Artery Aorta MXD3 0.36 0.22 enet 45 0.29 2.4e-16 -5.9 -5.1 3.1e-07 0.71 0.00 1.00 FALSE
3 GTEx Artery Tibial MXD3 0.12 0.13 enet 5 0.12 7.0e-10 -5.9 -6.1 1.3e-09 0.92 0.00 1.00 FALSE
4 GTEx Brain Cerebellum MXD3 0.28 0.31 lasso 2 0.30 1.6e-09 -5.9 -5.9 3.1e-09 0.92 0.00 1.00 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia MXD3 0.24 0.14 enet 10 0.25 2.9e-07 -5.9 -5.6 1.9e-08 0.83 0.00 0.98 FALSE
6 GTEx Breast Mammary Tissue MXD3 0.26 0.08 lasso 5 0.10 1.3e-05 -5.9 -5.5 3.1e-08 0.84 0.00 0.99 FALSE
7 GTEx Breast Mammary Tissue (Female) MXD3 0.23 0.08 lasso 3 0.09 1.1e-03 -6.0 -5.3 9.5e-08 0.76 0.01 0.85 FALSE
8 GTEx Colon Sigmoid MXD3 0.35 0.27 lasso 9 0.29 6.3e-11 -5.9 -5.8 5.7e-09 0.91 0.00 1.00 FALSE
9 GTEx Colon Transverse PRELID1 0.31 0.28 lasso 4 0.26 1.1e-12 -5.9 6.1 1.0e-09 -0.96 0.00 1.00 FALSE
10 GTEx Esophagus Gastroesophageal Junction MXD3 0.17 0.12 lasso 3 0.08 9.5e-04 -5.9 -5.8 8.7e-09 0.91 0.01 0.92 FALSE
11 GTEx Esophagus Mucosa MXD3 0.16 0.14 lasso 8 0.15 1.7e-10 -5.9 -5.8 7.6e-09 0.88 0.00 1.00 FALSE
12 GTEx Esophagus Muscularis MXD3 0.27 0.20 enet 10 0.24 1.6e-14 -5.9 -6.0 2.1e-09 0.93 0.00 1.00 FALSE
13 GTEx Heart Atrial Appendage MXD3 0.33 0.15 enet 24 0.16 1.5e-07 -5.9 -5.3 1.2e-07 0.76 0.00 1.00 FALSE
14 GTEx Heart Left Ventricle MXD3 0.17 0.03 lasso 3 0.03 1.5e-02 -5.9 -5.9 2.8e-09 0.92 0.00 0.97 FALSE
15 GTEx Liver PRELID1 0.22 0.25 lasso 3 0.24 2.4e-07 -6.0 6.1 1.3e-09 -0.95 0.00 0.99 FALSE
16 GTEx Lung MXD3 0.20 0.12 lasso 10 0.12 1.8e-09 -5.9 -5.6 2.7e-08 0.90 0.00 1.00 FALSE
17 GTEx Nerve Tibial MXD3 0.26 0.17 lasso 7 0.28 6.9e-20 -5.9 -5.6 2.1e-08 0.86 0.00 1.00 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic MXD3 0.22 0.18 lasso 3 0.17 1.8e-09 -5.9 -6.1 1.0e-09 0.96 0.00 1.00 FALSE
19 GTEx Skin Sun Exposed Lower leg PRELID1 0.06 0.02 enet 5 0.03 3.4e-03 -5.9 5.7 1.6e-08 -0.92 0.01 0.99 FALSE
20 GTEx Skin Sun Exposed Lower leg MXD3 0.19 0.14 lasso 6 0.12 4.2e-10 -6.0 -5.9 4.3e-09 0.88 0.00 1.00 FALSE
21 GTEx Small Intestine Terminal Ileum PRELID1 0.47 0.16 enet 10 0.13 7.6e-04 -6.0 6.5 7.9e-11 -0.94 0.00 0.96 TRUE
22 GTEx Thyroid MXD3 0.31 0.17 lasso 8 0.24 1.1e-18 -5.9 -5.9 4.2e-09 0.90 0.00 1.00 FALSE
23 METSIM Adipose MXD3 0.18 0.18 lasso 3 0.21 1.3e-30 -5.9 -6.0 2.6e-09 0.88 0.01 0.99 FALSE
24 YFS Blood PRELID1 0.18 0.14 enet 18 0.18 4.0e-58 -5.8 5.3 1.3e-07 -0.78 0.02 0.98 FALSE
25 The Cancer Genome Atlas Colon Adenocarcinoma PRELID1 0.09 0.01 blup 38 0.05 1.1e-03 -6.2 5.6 2.5e-08 -0.80 0.00 0.93 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRELID1 0.24 0.11 lasso 5 0.10 1.2e-11 -6.2 6.0 2.1e-09 -0.98 0.00 1.00 FALSE
27 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRELID1 0.33 0.08 enet 4 0.08 2.7e-05 -5.9 6.1 1.0e-09 -0.96 0.00 0.99 FALSE
28 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PRELID1 0.08 0.10 lasso 4 0.07 2.9e-04 -5.8 5.9 2.9e-09 -0.88 0.01 0.96 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma MXD3 0.04 0.02 blup 40 0.03 2.8e-04 -5.9 -5.2 2.3e-07 0.88 0.02 0.96 FALSE