[Hub]/) : Traits : Tanning :

chr6:145,125,929-146,983,441

Best TWAS P=2.41e-10 · Best GWAS P=9.52e-12 conditioned to 0.00979

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC100507557 0.09 0.18 enet 22 0.21 1.3e-24 6.0 6.2 5.8e-10 -0.76 0.39 0.61 FALSE
2 GTEx Adrenal Gland RP11-545I5.3 0.08 0.09 enet 10 0.03 2.5e-02 5.9 6.0 2.4e-09 -0.77 0.14 0.48 FALSE
3 GTEx Cells Transformed fibroblasts FBXO30 0.04 0.04 lasso 1 0.04 4.6e-04 5.9 -5.9 4.4e-09 0.80 0.21 0.34 FALSE
4 GTEx Cells Transformed fibroblasts RP11-545I5.3 0.04 0.03 lasso 2 0.03 2.0e-03 -4.3 5.3 1.3e-07 -0.64 0.14 0.68 FALSE
5 GTEx Esophagus Mucosa RP11-545I5.3 0.07 0.03 lasso 4 0.04 1.4e-03 -4.3 5.3 1.5e-07 -0.66 0.09 0.73 FALSE
6 GTEx Esophagus Muscularis EPM2A 0.11 0.09 enet 21 0.10 7.0e-07 6.0 5.4 6.1e-08 -0.77 0.17 0.83 FALSE
7 GTEx Esophagus Muscularis RP11-545I5.3 0.10 0.13 lasso 6 0.12 5.9e-08 5.9 5.5 3.8e-08 -0.72 0.41 0.59 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic EPM2A 0.19 0.15 lasso 5 0.15 2.0e-08 6.4 -6.2 5.5e-10 0.88 0.05 0.95 FALSE
9 GTEx Skin Sun Exposed Lower leg EPM2A 0.03 0.03 enet 10 0.01 2.4e-02 6.5 -6.3 2.4e-10 0.89 0.13 0.74 TRUE
10 GTEx Testis EPM2A 0.14 0.14 lasso 3 0.13 1.8e-06 5.9 6.1 1.2e-09 -0.82 0.28 0.68 FALSE
11 NTR Blood EPM2A 0.02 0.02 lasso 3 0.02 2.7e-06 6.5 -5.7 1.2e-08 0.82 0.03 0.97 FALSE
12 YFS Blood SHPRH 0.01 0.01 blup 307 0.01 1.0e-04 5.8 6.0 2.6e-09 -0.84 0.17 0.82 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma FBXO30 0.02 0.02 blup 27 0.01 4.6e-04 6.0 5.3 9.1e-08 -0.64 0.03 0.79 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EPM2A 0.03 0.01 enet 10 0.01 1.2e-02 6.3 -5.2 1.9e-07 0.81 0.01 0.82 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EPM2A 0.04 0.04 enet 9 0.02 1.5e-03 6.2 -5.8 5.2e-09 0.84 0.01 0.98 FALSE
16 The Cancer Genome Atlas Liver Hepatocellular Carcinoma EPM2A 0.28 0.04 enet 7 0.03 1.3e-02 5.8 -5.5 4.9e-08 0.72 0.01 0.49 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma EPM2A 0.21 0.07 blup 44 0.07 4.6e-07 6.2 -6.2 4.2e-10 0.83 0.01 0.99 FALSE