Best TWAS P=1.85e-10 · Best GWAS P=1.09e-29 conditioned to 9.44e-28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | AHR | 0.23 | 0.02 | lasso | 7 | 0.05 | 4.6e-03 | 5.1 | -5.3 | 1.3e-07 | -0.04 | 0.12 | 0.04 | FALSE |
| 2 | GTEx | Testis | AC003075.4 | 0.39 | 0.32 | enet | 17 | 0.35 | 1.8e-16 | 5.8 | 5.6 | 1.9e-08 | -0.04 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AHR | 0.01 | 0.01 | blup | 39 | 0.01 | 3.1e-03 | 5.9 | 6.1 | 8.7e-10 | -0.02 | 0.09 | 0.56 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | AHR | 0.10 | 0.09 | lasso | 3 | 0.12 | 3.7e-13 | 5.9 | -6.4 | 1.9e-10 | 0.07 | 0.37 | 0.63 | TRUE |