Best TWAS P=5.87e-09 · Best GWAS P=7.83e-12 conditioned to 0.000269
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP5-1042I8.7 | 0.17 | 0.00 | lasso | 11 | 0.03 | 0.01400 | 5.7 | 5.8 | 7.8e-09 | 0.90 | 0.36 | 0.56 | FALSE |
| 2 | GTEx | Artery Coronary | RP5-1042I8.7 | 0.11 | 0.07 | lasso | 2 | 0.04 | 0.01750 | 5.7 | 5.8 | 5.9e-09 | 0.89 | 0.08 | 0.63 | TRUE |
| 3 | GTEx | Liver | NOTCH2 | 0.14 | 0.13 | lasso | 2 | 0.10 | 0.00076 | 5.7 | -5.6 | 2.7e-08 | -0.89 | 0.05 | 0.71 | FALSE |