[Hub]/) : Traits : Tanning :

chr1:65,294,331-67,944,069

Best TWAS P=8.07e-23 · Best GWAS P=9.61e-57 conditioned to 3.87e-22

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PDE4B 0.15 0.10 lasso 10 0.11 3.7e-13 10.2 -9.8 8.1e-23 -0.56 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex TCTEX1D1 0.06 0.00 bslmm 574 0.03 5.1e-05 -2.9 6.5 9.1e-11 0.52 0.47 0.13 FALSE
3 GTEx Cells Transformed fibroblasts SGIP1 0.19 0.01 enet 22 0.10 3.8e-08 2.3 6.9 6.9e-12 0.29 0.51 0.29 FALSE
4 ROSMAP Brain Pre-frontal Cortex LEPR 0.09 0.07 blup 505 0.06 4.6e-08 -4.0 5.7 1.1e-08 0.14 1.00 0.00 TRUE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDE4B 0.03 0.00 blup 320 0.01 3.5e-02 -5.2 -9.3 2.0e-20 -0.40 0.06 0.68 TRUE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGIP1 0.06 0.02 blup 240 0.04 5.4e-05 -2.3 5.2 2.1e-07 0.21 0.55 0.02 TRUE