[Hub]/) : Traits : Tanning :

chr8:144,294,773-145,744,618

Best TWAS P=2.17e-09 · Best GWAS P=7.46e-08 conditioned to 0.31

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLEC 0.05 0.07 enet 9 0.07 8.5e-09 -5.2 5.7 1.5e-08 -0.95 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous PLEC 0.14 0.14 enet 13 0.16 6.2e-13 -5.1 5.2 1.6e-07 -0.93 0.02 0.98 FALSE
3 GTEx Artery Aorta PLEC 0.18 0.16 lasso 3 0.16 2.6e-09 -5.3 5.3 1.4e-07 -0.92 0.01 0.99 FALSE
4 GTEx Artery Tibial PLEC 0.19 0.17 lasso 2 0.20 2.2e-15 -5.3 5.2 1.7e-07 -0.92 0.01 0.99 FALSE
5 GTEx Brain Cerebellar Hemisphere PLEC 0.20 0.21 enet 12 0.22 2.2e-06 -4.9 5.4 5.7e-08 -0.93 0.02 0.97 FALSE
6 GTEx Brain Cerebellum PLEC 0.33 0.15 enet 16 0.15 2.6e-05 -5.4 5.2 1.9e-07 -0.96 0.01 0.99 FALSE
7 GTEx Breast Mammary Tissue PLEC 0.17 0.20 lasso 4 0.22 1.3e-11 -5.2 5.2 2.6e-07 -0.94 0.02 0.98 FALSE
8 GTEx Breast Mammary Tissue (Male) PLEC 0.24 0.19 lasso 4 0.18 5.3e-05 -5.1 5.2 1.8e-07 -0.94 0.02 0.95 FALSE
9 GTEx Breast Mammary Tissue (Female) PLEC 0.19 0.17 lasso 2 0.17 7.9e-06 -4.9 5.2 2.5e-07 -0.94 0.02 0.94 FALSE
10 GTEx Cells Transformed fibroblasts PLEC 0.30 0.30 lasso 4 0.40 4.0e-32 -5.2 5.2 2.0e-07 -0.93 0.02 0.98 FALSE
11 GTEx Esophagus Mucosa PARP10 0.08 0.03 enet 17 0.04 1.0e-03 -4.6 6.0 2.2e-09 -0.80 0.08 0.80 TRUE
12 GTEx Lung PLEC 0.26 0.29 lasso 6 0.30 2.6e-23 -5.3 5.2 2.1e-07 -0.92 0.01 0.99 FALSE
13 GTEx Pituitary PLEC 0.31 0.39 lasso 4 0.44 2.7e-12 -4.9 5.2 2.2e-07 -0.96 0.02 0.98 FALSE
14 GTEx Skin Sun Exposed Lower leg PLEC 0.05 0.03 lasso 4 0.03 2.4e-03 -5.3 5.2 2.2e-07 -0.95 0.03 0.87 FALSE
15 GTEx Testis PLEC 0.25 0.23 lasso 7 0.27 1.9e-12 -5.2 5.2 2.1e-07 -0.95 0.02 0.98 FALSE
16 GTEx Thyroid PLEC 0.20 0.26 lasso 7 0.29 9.2e-23 -4.8 5.2 2.6e-07 -0.92 0.02 0.98 FALSE
17 GTEx Whole Blood PLEC 0.15 0.15 enet 9 0.19 2.1e-17 -5.4 5.3 1.2e-07 -0.98 0.01 0.99 FALSE