[Hub]/) : Traits : Tanning :

chr9:11,988,659-13,977,570

Best TWAS P=9.23e-63 · Best GWAS P=3.03e-81 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TYRP1 0.13 0.03 enet 19 0.07 2.0e-09 8.96 -14.1 3.7e-45 -0.58 0.99 0.01 TRUE
2 GTEx Artery Aorta LURAP1L 0.25 0.00 enet 25 0.02 2.5e-02 -1.68 -7.7 1.7e-14 -0.48 0.06 0.55 TRUE
3 GTEx Brain Caudate basal ganglia LURAP1L 0.23 0.07 lasso 5 0.01 1.7e-01 15.78 -16.4 2.9e-60 -0.80 0.02 0.86 FALSE
4 GTEx Pituitary MPDZ 0.44 -0.01 enet 14 -0.01 5.7e-01 0.74 -7.1 1.4e-12 -0.32 0.06 0.13 TRUE
5 ROSMAP Brain Pre-frontal Cortex TYRP1 0.10 0.03 lasso 6 0.04 4.1e-06 14.95 7.1 9.9e-13 0.54 0.96 0.01 TRUE
6 ROSMAP Brain Pre-frontal Cortex LURAP1L 0.31 0.32 lasso 9 0.32 1.9e-42 16.73 -16.7 9.2e-63 -0.84 1.00 0.00 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma C9orf150 0.06 0.04 lasso 2 0.06 6.2e-07 9.72 -15.4 9.0e-54 -0.74 0.01 0.99 TRUE
8 The Cancer Genome Atlas Lung Adenocarcinoma TYRP1 0.03 0.03 lasso 3 0.03 6.7e-05 13.22 14.7 5.6e-49 0.81 0.24 0.62 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TYRP1 0.02 0.01 blup 62 0.01 1.7e-02 13.37 11.4 4.3e-30 0.71 0.04 0.15 FALSE