Best TWAS P=1.08e-09 · Best GWAS P=7.61e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CNTN1 | 0.20 | 0.18 | lasso | 9 | 0.16 | 1.5e-10 | -5.9 | 6.0 | 2.0e-09 | -0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | CNTN1 | 0.58 | 0.49 | lasso | 7 | 0.50 | 6.5e-31 | -6.0 | 6.0 | 1.7e-09 | -0.98 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CNTN1 | 0.53 | 0.56 | lasso | 5 | 0.56 | 3.6e-56 | -6.1 | 6.1 | 1.1e-09 | -0.99 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CNTN1 | 0.27 | 0.31 | lasso | 2 | 0.31 | 3.9e-35 | -5.9 | 6.0 | 2.1e-09 | -0.98 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CNTN1 | 0.10 | 0.07 | lasso | 2 | 0.06 | 7.6e-08 | -6.1 | 6.0 | 2.4e-09 | -0.98 | 0.01 | 0.99 | FALSE |