Best TWAS P=1.1e-35 · Best GWAS P=1.21e-38 conditioned to 0.0013
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TMTC3 | 0.05 | 0.00 | enet | 27 | 0.04 | 2.4e-05 | 1.01 | -6.7 | 1.9e-11 | 0.33 | 0.56 | 0.17 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | TMTC3 | 0.35 | 0.05 | enet | 39 | 0.19 | 6.9e-11 | 0.97 | -9.5 | 2.8e-21 | 0.39 | 0.14 | 0.83 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | TMTC3 | 0.13 | 0.04 | lasso | 4 | 0.09 | 7.9e-08 | 0.95 | -5.7 | 1.2e-08 | 0.37 | 0.97 | 0.02 | TRUE |
| 4 | GTEx | Testis | TMTC3 | 0.19 | 0.17 | lasso | 3 | 0.14 | 6.2e-07 | -12.50 | -12.5 | 1.1e-35 | 0.93 | 0.34 | 0.62 | TRUE |