[Hub]/) : Traits : Alzheimer’s Disease (including proxy) :

chr17:60,858,059-62,279,811

Best TWAS P=4.89e-09 · Best GWAS P=2.86e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ACE 0.08 0.05 lasso 4 0.04 1.0e-05 -5.5 -5.8 6.4e-09 0.82 0 1.00 FALSE
2 GTEx Colon Transverse ACE 0.31 0.28 lasso 2 0.28 1.8e-13 -5.5 5.9 4.9e-09 -0.98 0 1.00 TRUE
3 The Cancer Genome Atlas Colon Adenocarcinoma ACE 0.34 0.22 lasso 5 0.22 6.5e-13 -4.6 5.2 2.1e-07 -0.94 0 0.99 FALSE
4 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ACE 0.16 0.08 lasso 2 0.07 5.8e-05 -4.6 5.3 1.3e-07 -0.96 0 0.99 FALSE
5 The Cancer Genome Atlas Pancreatic Adenocarcinoma ACE 0.13 0.14 lasso 1 0.10 6.6e-05 -5.5 5.5 2.9e-08 -1.00 0 0.99 FALSE
6 The Cancer Genome Atlas Rectum Adenocarcinoma ACE 0.16 0.14 lasso 6 0.13 5.1e-04 -5.5 5.5 3.1e-08 -0.95 0 0.84 FALSE