Best TWAS P=1.3e-08 · Best GWAS P=2.52e-11 conditioned to 0.00015
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | EPHA1-AS1 | 0.06 | 0.03 | bslmm | 250 | 0.02 | 0.00049 | -3.1 | -5.1 | 2.6e-07 | -0.32 | 0.02 | 0.78 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZYX | 0.07 | 0.00 | blup | 77 | 0.02 | 0.00212 | -2.2 | -5.7 | 1.3e-08 | -0.52 | 0.01 | 0.55 | TRUE |