Best TWAS P=6.09e-15 · Best GWAS P=1.38e-24 conditioned to 4.76e-27
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | PTK2B | 0.03 | 0.02 | lasso | 2 | 0.02 | 2.1e-07 | 7.8 | 7.8 | 6.1e-15 | 0.07 | 0.99 | 0.00 | TRUE |
| 2 | YFS | Blood | PTK2B | 0.09 | 0.08 | lasso | 5 | 0.09 | 7.8e-28 | 7.8 | 6.7 | 2.0e-11 | 0.12 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PTK2B | 0.08 | 0.06 | lasso | 2 | 0.05 | 9.4e-07 | -5.5 | 5.5 | 4.2e-08 | -0.01 | 0.38 | 0.59 | FALSE |