Best TWAS P=6.84e-13 · Best GWAS P=2.19e-28 conditioned to 1.72e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | FBXO18 | 0.10 | 0.00 | lasso | 5 | 0.00 | 5.5e-01 | -8.3 | -6.0 | 2.4e-09 | -0.06 | 0.17 | 0.05 | FALSE |
| 2 | METSIM | Adipose | IL2RA | 0.07 | 0.02 | lasso | 3 | 0.02 | 1.0e-03 | 5.7 | 6.4 | 2.0e-10 | 0.14 | 0.54 | 0.02 | TRUE |
| 3 | YFS | Blood | PRKCQ | 0.04 | 0.03 | lasso | 3 | 0.02 | 9.7e-09 | 6.1 | -5.8 | 6.1e-09 | -0.04 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | IL2RA | 0.09 | 0.03 | enet | 8 | 0.05 | 9.8e-05 | -6.1 | -7.2 | 6.8e-13 | -0.20 | 0.09 | 0.06 | TRUE |