Best TWAS P=2.09e-09 · Best GWAS P=1.22e-18 conditioned to 1.53e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | HECTD4 | 0.05 | 0.02 | lasso | 3 | 0.01 | 3.1e-02 | -7.9 | -5.7 | 9.6e-09 | 0.78 | 0.02 | 0.91 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | ADAM1A | 0.21 | 0.01 | enet | 29 | 0.03 | 6.8e-02 | 1.7 | -6.0 | 2.1e-09 | 0.40 | 0.04 | 0.16 | TRUE |
| 3 | NTR | Blood | ALDH2 | 0.06 | 0.01 | blup | 222 | 0.02 | 4.3e-08 | 2.1 | 5.7 | 1.1e-08 | -0.44 | 0.97 | 0.02 | FALSE |
| 4 | YFS | Blood | TRAFD1 | 0.04 | 0.02 | lasso | 2 | 0.01 | 2.9e-05 | -5.0 | -6.0 | 2.5e-09 | 0.54 | 0.05 | 0.92 | TRUE |