Best TWAS P=1.48e-22 · Best GWAS P=1.01e-31 conditioned to 4.87e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | SMAD3 | 0.19 | 0.02 | enet | 3 | 0.03 | 2.3e-03 | 11.7 | -8.3 | 8.6e-17 | -0.75 | 0.00 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | SMAD3 | 0.22 | 0.12 | enet | 12 | 0.11 | 5.2e-11 | 9.5 | -9.8 | 1.5e-22 | -0.88 | 0.01 | 0.99 | TRUE |