Best TWAS P=2.04e-09 · Best GWAS P=1.03e-09 conditioned to 0.00905
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | PPCDC | 0.07 | 0.00 | enet | 8 | -0.01 | 7.9e-01 | -6.1 | -5.3 | 1.5e-07 | 0.89 | 0.02 | 0.50 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | MPI | 0.06 | 0.01 | enet | 4 | 0.03 | 5.7e-02 | -5.2 | 5.2 | 1.6e-07 | -0.52 | 0.03 | 0.06 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | SCAMP2 | 0.26 | 0.06 | lasso | 9 | 0.06 | 6.2e-03 | -6.0 | 6.0 | 2.0e-09 | -0.71 | 0.02 | 0.72 | TRUE |
| 4 | METSIM | Adipose | MPI | 0.08 | 0.06 | blup | 273 | 0.07 | 3.1e-11 | -4.2 | 5.5 | 4.9e-08 | -0.79 | 0.04 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C15orf39 | 0.03 | 0.01 | blup | 16 | 0.01 | 5.4e-02 | -6.0 | -5.6 | 2.4e-08 | 0.71 | 0.00 | 0.91 | FALSE |