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chr17:34,146,026-35,644,076

Best TWAS P=6.26e-09 · Best GWAS P=1.28e-08 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GGNBP2	0.10	0.11	enet	9	0.11	3.5e-09	-5.7	5.7	1.5e-08	-0.97	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	MYO19	0.07	0.05	enet	10	0.03	1.3e-03	-5.3	-5.2	1.9e-07	0.96	0.01	0.99	FALSE
3	GTEx	Artery Aorta	MYO19	0.20	0.16	enet	9	0.15	1.6e-08	4.4	-5.2	1.7e-07	0.93	0.02	0.98	FALSE
4	GTEx	Artery Tibial	MYO19	0.12	0.11	lasso	6	0.13	4.1e-10	-5.4	-5.2	2.6e-07	0.93	0.02	0.98	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	ZNHIT3	0.31	0.32	enet	9	0.22	1.1e-07	-5.3	-5.4	6.3e-08	0.98	0.01	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	ZNHIT3	0.15	0.07	lasso	7	0.05	1.7e-04	-5.6	-5.8	6.3e-09	0.96	0.01	0.99	TRUE
7	GTEx	Esophagus Mucosa	GGNBP2	0.16	0.16	enet	15	0.18	3.1e-12	4.6	5.1	2.9e-07	-0.90	0.04	0.96	FALSE
8	GTEx	Esophagus Mucosa	DHRS11	0.12	0.08	lasso	2	0.06	5.1e-05	-4.9	-5.1	3.1e-07	0.90	0.10	0.90	FALSE
9	GTEx	Esophagus Mucosa	MYO19	0.11	0.08	enet	12	0.04	1.2e-03	-5.3	-5.2	1.8e-07	0.96	0.01	0.99	FALSE
10	GTEx	Esophagus Muscularis	MYO19	0.14	0.14	enet	8	0.15	2.8e-09	-4.9	-5.5	5.1e-08	0.97	0.01	0.99	FALSE
11	GTEx	Lung	GGNBP2	0.08	0.01	enet	8	0.01	3.3e-02	-4.9	5.5	3.7e-08	-0.91	0.03	0.96	FALSE
12	GTEx	Lung	MYO19	0.15	0.14	enet	8	0.13	2.1e-10	-5.3	-5.4	5.8e-08	0.97	0.01	0.99	FALSE
13	GTEx	Nerve Tibial	GGNBP2	0.10	0.04	lasso	3	0.05	2.4e-04	-5.7	5.7	1.6e-08	-0.98	0.01	0.99	FALSE
14	GTEx	Nerve Tibial	MYO19	0.11	0.11	enet	8	0.08	1.4e-06	-5.4	-5.5	5.0e-08	0.96	0.01	0.99	FALSE
15	GTEx	Testis	ZNHIT3	0.27	0.33	lasso	2	0.32	8.0e-15	-5.3	5.3	1.3e-07	-0.97	0.02	0.98	FALSE
16	METSIM	Adipose	GGNBP2	0.16	0.14	lasso	5	0.14	6.2e-21	-5.3	5.3	9.2e-08	-0.97	0.01	0.99	FALSE
17	METSIM	Adipose	MYO19	0.10	0.10	lasso	4	0.10	1.6e-14	-5.6	-5.7	1.3e-08	0.97	0.00	1.00	FALSE
18	YFS	Blood	GGNBP2	0.07	0.09	enet	21	0.10	4.7e-31	-5.4	5.2	1.6e-07	-0.93	0.01	0.99	FALSE
19	YFS	Blood	MYO19	0.12	0.14	enet	14	0.14	4.0e-45	-5.3	-5.4	7.4e-08	0.97	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GGNBP2	0.04	0.04	enet	3	0.04	6.3e-05	-5.7	5.5	3.8e-08	-0.95	0.00	1.00	FALSE