Best TWAS P=6.27e-09 · Best GWAS P=4.4e-09 conditioned to 0.367
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TOM1L2 | 0.10 | 0.06 | lasso | 5 | 0.02 | 6.6e-02 | 5.20 | -5.6 | 2.4e-08 | -0.80 | 0.08 | 0.66 | FALSE |
| 2 | GTEx | Liver | PEMT | 0.25 | -0.01 | enet | 11 | 0.01 | 1.5e-01 | -0.99 | -5.8 | 6.3e-09 | -0.60 | 0.03 | 0.53 | TRUE |
| 3 | GTEx | Nerve Tibial | TOM1L2 | 0.11 | 0.04 | enet | 43 | 0.10 | 1.5e-07 | 4.84 | -5.3 | 1.4e-07 | -0.58 | 0.23 | 0.76 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SREBF1 | 0.04 | 0.03 | blup | 32 | 0.02 | 7.8e-03 | 5.22 | 5.5 | 3.8e-08 | 0.77 | 0.01 | 0.84 | FALSE |