TWAS hub - MYO19

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0520	0.0180	4.2e-04	0.054	0.034	0.046	0.038	0.050	3.2e-07	4.4e-05	2.8e-06	1.9e-05	8.4e-07
2	GTEx	Adipose Subcutaneous	0.0690	0.0280	1.3e-03	0.052	NA	0.031	NA	0.003	4.3e-05	NA	1.3e-03	NA	1.8e-01
3	GTEx	Adipose Visceral Omentum	0.1220	0.0540	8.7e-03	0.021	NA	0.027	NA	0.037	2.9e-02	NA	1.4e-02	NA	5.2e-03
4	GTEx	Artery Aorta	0.2020	0.0640	6.9e-06	0.163	NA	0.148	NA	0.033	2.7e-09	NA	1.6e-08	NA	6.4e-03
5	GTEx	Artery Tibial	0.1185	0.0308	1.5e-07	0.106	NA	0.122	NA	0.127	1.2e-08	NA	8.7e-10	NA	4.1e-10
6	GTEx	Colon Transverse	0.1320	0.0480	6.0e-04	0.125	NA	0.096	NA	0.108	1.5e-06	NA	2.6e-05	NA	8.0e-06
7	GTEx	Esophagus Mucosa	0.1080	0.0390	4.1e-04	0.076	NA	0.039	NA	0.027	8.3e-06	NA	1.2e-03	NA	6.3e-03
8	GTEx	Esophagus Muscularis	0.1400	0.0400	3.8e-06	0.135	NA	0.148	NA	0.120	1.4e-08	NA	2.8e-09	NA	9.7e-08
9	GTEx	Heart Atrial Appendage	0.1320	0.0490	1.2e-03	0.125	NA	0.092	NA	0.111	3.1e-06	NA	6.6e-05	NA	1.1e-05
10	GTEx	Heart Left Ventricle	0.0975	0.0409	3.1e-03	0.061	NA	0.010	NA	0.036	3.8e-04	NA	8.9e-02	NA	5.4e-03
11	GTEx	Lung	0.1520	0.0384	3.0e-08	0.142	NA	0.134	NA	0.125	5.0e-11	NA	2.1e-10	NA	8.6e-10
12	GTEx	Muscle Skeletal	0.0443	0.0202	6.8e-03	0.046	NA	0.029	NA	0.023	2.3e-05	NA	6.4e-04	NA	2.4e-03
13	GTEx	Nerve Tibial	0.1139	0.0342	2.4e-05	0.110	NA	0.085	NA	0.017	3.2e-08	NA	1.4e-06	NA	2.1e-02
14	GTEx	Skin Sun Exposed Lower leg	0.0740	0.0330	4.8e-03	0.009	NA	0.029	NA	-0.001	5.8e-02	NA	1.8e-03	NA	4.1e-01
15	GTEx	Spleen	0.5740	0.1010	4.0e-05	0.194	NA	0.118	NA	0.177	1.1e-05	NA	6.1e-04	NA	2.6e-05
16	GTEx	Thyroid	0.1110	0.0440	1.3e-03	0.054	NA	0.010	NA	0.037	5.4e-05	NA	5.1e-02	NA	7.1e-04
17	METSIM	Adipose	0.0970	0.0245	1.7e-09	0.104	0.063	0.096	0.088	0.098	3.0e-15	8.8e-10	3.3e-14	4.9e-13	1.6e-14
18	YFS	Blood	0.1207	0.0201	0.0e+00	0.141	0.117	0.145	0.141	0.142	6.4e-44	4.5e-36	4.0e-45	1.1e-43	3.8e-44

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Maternal smoking around birth	15.1	21.8	26.9	5.0	5.0	2.3	5.2	5.0	4.1	4.6	4.9	4.7	4.7	5.0	4.8	4.8	5.1	2.7	4.9	5.0	4.9
Waist circumference	14.0	51.1	65.1	7.1	7.9	4.9	6.8	8.1	7.5	7.3	7.8	7.3	7.5	7.5	7.2	7.6	7.2	3.9	6.7	7.8	7.3
Verbal and Numeric Reasoning (VNR)	12.7	30.4	38.1	-5.7	-5.6	-3.2	-6.1	-5.9	-5.5	-5.8	-6.0	-5.8	-6.2	-5.8	-5.5	-5.7	-6.0	-1.2	-5.5	-6.0	-5.5
Body mass index (BMI)	12.2	51.9	67.6	7.5	8.0	5.4	6.9	8.2	7.7	7.0	7.8	7.7	7.8	7.3	7.0	7.3	7.1	3.5	7.2	7.7	7.2
Leg fat mass (right)	11.9	46.3	61.8	6.9	7.5	4.9	6.5	7.9	7.4	6.9	7.5	7.2	7.3	7.0	6.6	7.1	6.7	3.1	6.5	7.4	6.8
Leg fat mass (left)	11.8	46.0	61.5	6.9	7.5	4.9	6.4	7.8	7.4	6.8	7.5	7.2	7.3	6.9	6.5	7.0	6.7	3.1	6.5	7.3	6.7
Arm fat mass (left)	11.0	45.1	57.8	6.9	7.4	5.0	6.3	7.6	7.0	6.8	7.3	6.9	7.1	7.0	6.4	6.9	6.7	3.5	6.5	7.3	6.9
Arm fat mass (right)	10.8	44.3	57.6	6.8	7.4	5.0	6.2	7.6	7.0	6.7	7.3	7.0	7.0	7.0	6.4	6.8	6.6	3.4	6.4	7.2	6.8
Arm fat percentage (right)	10.6	41.8	53.6	6.6	7.2	5.0	6.0	7.3	6.7	6.6	7.1	6.7	6.8	6.8	6.2	6.7	6.5	2.9	6.2	7.0	6.7
Illnesses of mother	10.2	12.6	18.9	-3.6	-3.9	-2.1	-3.4	-4.2	-3.5	-3.5	-4.0	-4.3	-3.8	-3.6	-4.3	-3.6	-3.2	-1.2	-3.3	-3.6	-3.1
Intelligence (Savage-Jansen 2018)	10.0	30.9	38.6	-5.7	-5.6	-4.7	-6.0	-5.9	-5.3	-6.0	-6.1	-5.7	-5.9	-5.9	-5.1	-6.0	-5.6	-1.4	-5.5	-6.2	-5.7
BMI	10.0	57.7	73.6	7.8	8.5	5.8	7.2	8.6	8.2	7.5	8.3	8.0	8.0	7.8	7.4	7.9	7.3	3.8	7.6	8.1	7.6
Fluid intelligence score	10.0	20.8	26.4	-4.7	-4.6	-2.9	-5.0	-4.9	-4.7	-4.9	-5.0	-5.0	-5.1	-4.7	-5.1	-4.5	-4.7	0.0	-4.5	-4.9	-4.2
Whole body fat mass	9.8	40.9	54.9	6.4	7.1	4.5	5.9	7.4	6.9	6.5	7.0	6.5	6.7	6.7	6.0	6.7	6.4	3.5	6.0	7.1	6.5
Arm fat percentage (left)	9.8	39.0	50.4	6.3	6.9	4.8	5.7	7.1	6.6	6.4	6.8	6.4	6.6	6.6	5.9	6.5	6.3	3.1	5.9	6.8	6.5
Leg fat percentage (left)	9.7	35.0	46.9	5.9	6.5	3.7	5.6	6.8	6.5	5.9	6.6	6.3	6.4	6.0	5.9	6.3	5.8	2.6	5.6	6.4	5.8
Leg fat percentage (right)	9.6	34.7	46.6	5.9	6.5	3.8	5.5	6.8	6.3	6.0	6.5	6.2	6.3	6.1	5.9	6.3	5.8	2.7	5.5	6.4	5.9
Allergy or Eczema	8.9	23.5	32.4	-4.6	-5.2	-2.8	-5.2	-5.2	-4.5	-5.2	-5.5	-4.4	-5.0	-5.4	-5.0	-5.5	-4.7	-2.3	-4.4	-5.7	-5.4
Body fat percentage	8.7	34.4	46.6	5.8	6.5	3.9	5.3	6.8	6.4	6.0	6.5	6.1	6.3	6.2	5.6	6.2	5.8	3.2	5.4	6.5	6.0
Body Mass Index (BMI) (2010)	8.5	11.6	16.5	3.8	3.5	2.9	3.4	3.7	3.3	3.5	3.7	4.1	3.7	3.2	4.0	3.2	2.9	1.4	3.8	3.3	3.2
Comparative body size at age 10	8.0	22.0	32.0	5.2	5.2	4.1	4.5	5.7	4.7	4.1	5.1	5.5	5.0	4.4	4.9	4.4	4.6	1.5	5.0	4.7	4.3
Hayfever, allergic rhinitis or eczema	7.8	16.9	24.6	-3.4	-4.6	-2.1	-4.5	-4.3	-4.2	-4.7	-4.7	-3.7	-4.4	-4.6	-4.0	-4.5	-4.3	-1.2	-3.2	-5.0	-4.5
Trunk fat mass	7.8	33.5	45.1	5.7	6.4	4.1	5.2	6.7	6.2	5.9	6.4	5.8	6.0	6.1	5.4	6.1	5.7	3.3	5.3	6.5	6.0
High blood pressure (mother)	7.7	10.8	16.7	3.0	3.7	1.9	3.3	3.6	3.3	3.6	3.8	3.4	3.3	3.4	4.1	3.6	3.2	0.2	2.9	3.6	3.1
Noisy workplace	7.6	9.3	13.8	3.1	3.1	2.5	3.5	3.3	3.5	3.2	3.2	3.6	3.7	3.1	3.0	2.8	2.9	0.6	2.9	2.9	2.8
Weight	7.4	36.3	46.2	6.2	6.7	4.6	5.7	6.8	6.3	6.0	6.6	6.1	6.2	6.3	5.7	6.3	6.1	3.2	5.8	6.6	6.3
Trunk fat percentage	7.3	29.4	40.2	5.3	6.0	3.6	4.7	6.3	5.9	5.5	6.0	5.5	5.7	5.8	5.2	5.7	5.2	3.3	4.9	6.1	5.6
Qualifications: None of the above	6.7	14.3	19.8	4.0	4.1	1.8	3.7	4.5	3.6	4.2	4.1	3.9	4.0	4.1	4.2	3.7	3.6	1.6	3.8	4.1	3.8
Tense / ‘highly strung’	6.5	10.8	15.5	-3.4	-3.2	-1.8	-3.4	-3.1	-3.6	-3.6	-3.5	-3.6	-3.9	-3.4	-3.3	-3.3	-3.7	-0.9	-3.5	-3.3	-3.4
Qualifications: O levels/GCSEs or equivalent	5.9	9.4	13.9	-2.8	-3.3	-0.8	-2.6	-3.7	-3.7	-3.6	-3.5	-3.3	-3.3	-3.4	-2.8	-2.8	-3.2	-1.8	-2.6	-3.4	-3.1
Medication: Lansoprazole	5.7	6.5	11.3	1.9	2.8	1.0	2.6	2.5	3.4	2.9	3.0	2.3	3.2	2.9	1.7	2.8	2.5	0.7	1.8	3.0	2.9
Mother’s age at death	5.7	7.2	9.4	-2.5	-3.0	-1.5	-3.0	-3.1	-2.9	-2.9	-3.0	-2.8	-3.0	-2.7	-2.5	-2.9	-2.9	-0.3	-2.3	-2.7	-2.7
Irritability	5.7	9.7	12.4	-3.3	-3.5	-2.3	-3.4	-3.4	-3.0	-3.2	-3.3	-3.4	-3.5	-3.1	-3.5	-2.9	-3.1	-1.0	-3.3	-3.0	-3.0
Bipolar Disorder or Schizophrenia	5.5	13.4	16.6	-3.9	-3.7	-3.6	-4.0	-3.9	-3.4	-3.5	-4.1	-3.5	-3.8	-4.0	-3.3	-4.0	-3.3	-1.2	-3.7	-4.1	-4.0
Number of treatments/medications taken	5.5	10.0	15.8	3.0	3.5	1.1	2.8	3.2	3.3	4.0	3.4	3.1	3.3	3.5	2.9	3.7	3.5	1.2	2.9	3.5	3.5
Smoking status: Previous	5.4	8.0	13.1	2.4	3.1	2.0	3.2	2.9	3.2	3.2	3.0	2.5	2.7	3.2	2.0	3.2	3.6	-0.3	2.3	3.1	3.2
Hip circumference	5.3	22.7	29.7	4.8	5.2	3.4	4.4	5.5	5.4	4.6	5.3	5.1	5.2	4.8	4.4	4.9	4.8	2.7	4.5	5.2	4.8
Depression (Nagel 2018)	5.2	7.8	12.2	-2.8	-3.1	-1.5	-2.5	-2.9	-3.3	-2.7	-3.0	-3.4	-3.5	-2.5	-2.9	-2.2	-3.1	-2.3	-2.9	-2.6	-2.2
Medication: Paracetamol	5.2	8.7	11.2	3.0	3.0	2.3	2.8	3.3	2.9	3.3	3.2	2.9	2.8	3.1	2.9	3.3	3.0	1.3	2.9	3.2	3.0
Medication: Cholesterol lowering	4.8	7.5	12.7	1.9	2.9	1.4	2.6	2.5	3.3	3.3	3.1	2.2	2.9	3.1	2.0	3.2	3.2	1.6	1.9	3.6	3.1
Family relationship satisfaction	4.8	5.9	7.6	-2.4	-2.4	-1.7	-2.5	-2.6	-2.4	-2.5	-2.8	-2.5	-2.6	-2.5	-2.6	-2.6	-2.7	-0.8	-2.3	-2.7	-2.6
Medication: Metformin	4.6	6.4	9.1	2.3	2.5	3.0	2.8	2.4	2.5	2.4	2.6	2.8	2.9	2.4	2.0	2.7	2.6	2.4	2.3	2.4	2.5
Medication: Atenolol	4.6	5.7	10.4	2.2	2.5	0.5	2.4	2.6	2.0	2.7	2.5	1.4	1.9	2.9	1.7	3.2	3.1	1.7	1.9	2.9	3.2
Migraine (self-reported)	4.5	5.5	9.3	3.0	2.2	1.1	2.9	2.3	1.4	2.7	2.3	2.4	2.1	2.5	2.7	2.4	2.7	0.4	3.0	2.4	2.2
Friendships satisfaction	4.5	5.5	7.8	-2.6	-2.2	-2.8	-2.4	-2.3	-1.9	-2.4	-2.5	-2.4	-2.2	-2.3	-2.6	-2.3	-2.3	-0.6	-2.6	-2.7	-2.3
Unable to work because of sickness or disability	4.5	5.9	8.6	2.9	2.6	0.9	2.5	2.8	1.6	2.4	2.5	2.4	2.1	2.6	2.4	2.7	2.8	1.2	2.9	2.5	2.7
Bipolar Disorder (2018)	4.4	7.0	9.5	-2.9	-2.4	-3.1	-3.0	-2.9	-2.3	-2.6	-2.9	-2.4	-2.7	-2.9	-2.2	-2.9	-2.5	-0.3	-2.7	-2.9	-2.8
Ever used hormone-replacement therapy (HRT)	4.2	5.3	7.4	2.7	2.2	0.9	2.7	2.7	2.0	2.4	2.5	2.5	2.5	2.4	2.3	2.4	2.7	0.3	2.5	2.2	2.1
Allergy	4.1	9.4	14.0	2.3	3.3	2.1	3.4	3.2	3.6	3.5	3.6	2.9	3.4	3.3	3.1	3.0	3.1	1.1	2.1	3.7	3.1
Schizophrenia (2014)	4.0	8.8	11.7	-3.0	-2.9	-3.3	-3.0	-3.1	-3.4	-2.7	-3.3	-3.2	-3.4	-3.0	-2.8	-3.0	-2.8	-0.6	-2.9	-3.1	-3.1
Leg fat-free mass (left)	4.0	21.2	25.8	4.7	5.0	4.6	4.3	5.1	4.9	4.5	5.0	4.6	4.8	4.7	4.1	4.7	4.6	2.4	4.5	5.0	4.8
Leg predicted mass (left)	4.0	21.4	26.0	4.7	5.0	4.6	4.3	5.1	4.9	4.6	5.0	4.6	4.8	4.8	4.2	4.7	4.6	2.4	4.5	5.1	4.9
Medication for cholesterol	4.0	6.1	8.2	-2.7	-2.6	-0.9	-2.5	-2.6	-2.3	-2.6	-2.8	-2.7	-2.5	-2.6	-2.4	-2.9	-2.3	-1.8	-2.7	-2.5	-2.6
Arm predicted mass (left)	4.0	20.2	25.0	4.7	5.0	3.3	4.3	5.0	4.7	4.5	4.9	4.5	4.5	4.7	4.5	4.7	4.4	2.0	4.5	4.9	4.7
Father’s age at death	3.9	5.3	7.3	-2.5	-2.7	-2.5	-2.6	-2.7	-1.6	-2.2	-2.5	-2.4	-2.0	-2.3	-2.0	-2.5	-2.3	-0.1	-2.3	-2.3	-2.4
Medication for cholesterol, blood pressure or diabetes	3.9	6.4	10.1	-2.0	-2.8	-1.0	-2.3	-2.6	-3.0	-3.0	-2.9	-2.2	-2.7	-2.9	-1.8	-3.0	-3.0	-1.1	-1.9	-3.2	-2.7
Frequency of depressed mood in last 2 weeks	3.8	5.2	8.5	-2.1	-2.4	-1.7	-2.0	-2.1	-2.9	-2.5	-2.4	-2.5	-2.7	-2.3	-2.0	-1.9	-2.9	-1.7	-2.2	-2.2	-2.1
Serious illness, injury or assault of a close relative in last 2 years	3.8	4.4	5.6	-2.1	-2.4	-2.3	-2.1	-2.3	-2.3	-2.1	-2.4	-2.3	-2.4	-1.9	-2.3	-2.1	-1.9	-0.0	-2.0	-2.1	-1.8
Mouth/teeth dental problems: Bleeding gums	3.8	4.9	7.3	-2.6	-1.9	-1.4	-2.7	-2.3	-1.5	-2.3	-2.3	-2.0	-2.3	-2.4	-2.2	-2.6	-2.5	-0.6	-2.5	-2.3	-2.3
Qualifications: College or University degree	3.8	11.9	18.0	-3.8	-3.6	-2.3	-3.8	-4.2	-3.7	-3.1	-3.7	-3.8	-4.0	-3.5	-3.2	-3.3	-3.4	-0.1	-3.5	-3.7	-3.2
Neck or shoulder pain in last month	3.8	5.4	6.4	2.3	2.4	2.4	2.1	2.5	2.3	2.0	2.4	2.4	2.5	2.3	2.1	2.5	2.4	2.5	2.2	2.3	2.2
Medication: Paracetamol	3.8	5.9	9.2	2.4	2.5	1.9	2.2	2.6	2.7	3.0	2.7	2.4	2.4	2.5	2.2	2.6	2.4	1.3	2.4	2.5	2.4
Impedance of whole body	3.8	19.6	24.8	-4.7	-5.0	-4.5	-4.3	-4.9	-4.8	-4.1	-4.7	-5.0	-5.0	-4.1	-4.3	-4.2	-4.4	-1.2	-4.6	-4.4	-4.1
Arm fat-free mass (left)	3.7	18.8	23.3	4.6	4.8	3.3	4.2	4.8	4.5	4.2	4.7	4.5	4.4	4.5	4.3	4.4	4.2	2.0	4.5	4.7	4.5
Asthma	3.6	7.0	12.7	-2.2	-2.8	-3.5	-2.8	-3.0	-3.6	-2.6	-3.1	-2.7	-3.0	-2.6	-1.9	-2.2	-2.6	-0.7	-2.0	-2.9	-2.3
Reason for reducing amount of alcohol drunk: Health precaution	3.6	4.2	6.0	-1.9	-2.2	-1.2	-2.0	-2.2	-1.9	-2.3	-2.3	-1.8	-2.1	-2.4	-2.0	-2.0	-2.2	-1.0	-1.8	-2.4	-2.4
Asthma (self-reported)	3.6	7.2	13.4	-2.2	-2.8	-3.5	-2.8	-3.1	-3.7	-2.6	-3.1	-2.7	-3.1	-2.6	-1.9	-2.2	-2.7	-0.8	-1.9	-3.0	-2.3
Primary Biliary Cirrhosis	3.5	5.0	8.2	2.2	2.5	0.9	2.3	2.6	2.5	2.4	2.4	2.6	2.9	2.2	2.6	2.1	2.2	-0.1	2.1	2.1	1.8
Medication for pain relief, constipation, heartburn	3.5	5.9	9.0	-2.2	-2.5	-0.6	-2.3	-2.7	-2.5	-2.8	-2.6	-2.0	-2.3	-2.8	-2.1	-3.0	-2.6	-1.5	-2.0	-3.0	-2.9
Suffer from ‘nerves’	3.5	5.5	8.2	-2.6	-2.4	-1.0	-2.3	-2.8	-2.8	-2.5	-2.4	-2.6	-2.6	-2.3	-1.6	-2.0	-2.9	-1.9	-2.5	-2.1	-2.1
Medication: Atorvastatin	3.5	4.3	6.9	1.7	2.4	0.7	1.9	2.4	2.6	2.1	2.4	2.0	2.2	2.1	2.2	2.3	2.4	0.2	1.5	2.4	2.2
Basal metabolic rate	3.5	19.5	24.3	4.6	4.9	4.0	4.2	4.9	4.5	4.4	4.8	4.3	4.4	4.6	4.1	4.6	4.4	2.2	4.4	4.9	4.7
Waist Hip Ratio (WHR)	3.4	15.4	22.1	3.9	4.3	2.3	4.1	4.1	3.5	4.5	4.3	3.6	3.8	4.5	4.3	4.7	3.8	1.3	3.9	4.2	4.2
Leg fat-free mass (right)	3.4	18.2	21.9	4.4	4.7	4.3	4.0	4.7	4.6	4.1	4.7	4.2	4.4	4.3	3.8	4.3	4.2	2.1	4.2	4.6	4.5
Leg predicted mass (right)	3.4	18.1	21.9	4.4	4.7	4.3	4.0	4.7	4.5	4.1	4.7	4.2	4.4	4.3	3.8	4.3	4.2	2.2	4.2	4.6	4.5
Medication: Blood pressure	3.4	6.4	8.4	2.5	2.7	0.3	2.5	2.5	2.6	2.7	2.9	2.6	2.8	2.6	2.3	2.9	2.7	1.7	2.5	2.8	2.7
Impedance of leg (left)	3.3	16.1	21.5	-4.1	-4.4	-4.3	-3.7	-4.3	-4.6	-3.7	-4.2	-4.5	-4.6	-3.8	-3.6	-3.6	-4.2	-1.7	-4.1	-4.0	-3.8
Qualifications: A levels/AS levels or equivalent	3.3	7.3	11.8	-2.7	-2.9	-1.7	-2.6	-3.4	-3.4	-2.6	-3.0	-3.2	-3.3	-2.7	-2.3	-2.2	-2.7	1.2	-2.5	-2.8	-2.5
Impedance of arm (left)	3.3	15.3	21.0	-4.3	-4.4	-3.0	-4.1	-4.5	-4.4	-3.5	-4.1	-4.6	-4.4	-3.6	-4.0	-3.8	-3.8	-0.9	-4.2	-3.8	-3.4
Diastolic blood pressure, automated reading	3.3	10.3	14.4	3.2	3.4	2.4	3.1	3.5	3.2	3.1	3.8	3.6	3.4	3.3	3.4	3.1	3.2	0.7	3.1	3.7	3.3
Schizophrenia (2018)	3.2	6.7	8.5	-2.7	-2.8	-2.2	-2.7	-2.7	-2.4	-2.5	-2.9	-2.6	-2.7	-2.8	-2.5	-2.8	-2.3	-1.3	-2.6	-2.9	-2.9
Triglycerides	3.2	5.3	9.8	2.6	2.0	3.1	2.0	2.5	2.6	2.1	2.6	2.5	2.3	2.2	2.3	2.0	1.9	0.7	2.6	2.4	2.1
Coronary Artery Disease (CAD)	3.1	3.8	5.3	2.3	2.0	1.7	2.0	1.9	1.1	2.1	2.0	1.7	1.8	2.2	2.1	1.9	2.1	0.4	2.3	2.0	2.2
Impedance of leg (right)	3.1	14.9	21.2	-4.0	-4.2	-4.1	-3.6	-4.2	-4.6	-3.4	-4.1	-4.4	-4.6	-3.5	-3.6	-3.5	-3.8	-1.5	-4.0	-3.8	-3.5
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.1	7.5	-1.8	-2.1	-1.4	-1.9	-2.1	-2.7	-2.2	-2.2	-2.5	-2.6	-1.8	-1.6	-1.5	-2.4	-1.7	-1.7	-1.9	-1.6
Past tobacco smoking	3.1	5.7	10.4	-1.8	-2.7	-1.2	-2.6	-2.4	-3.0	-2.5	-2.7	-2.3	-2.4	-2.6	-1.6	-2.7	-3.2	0.1	-1.7	-2.7	-2.7
Medication: Simvastatin	3.1	4.6	8.1	1.8	2.2	1.1	2.0	2.0	2.1	2.9	2.4	2.1	2.3	2.5	2.1	2.5	1.9	0.9	1.8	2.6	2.3
High cholesterol (Self-reported)	3.1	5.6	9.3	1.8	2.6	1.2	2.2	2.3	2.5	2.9	2.8	2.2	2.5	2.8	1.5	2.8	2.3	1.6	1.7	3.0	2.7
Respiratory disease	3.0	6.7	10.8	-2.1	-2.6	-3.3	-2.8	-2.9	-3.3	-2.5	-3.1	-2.4	-2.8	-2.6	-2.2	-2.2	-2.8	0.2	-1.8	-3.0	-2.6
Mouth/teeth dental problems: Dentures	3.0	5.0	7.6	2.4	2.3	1.3	2.5	2.3	1.8	1.9	2.3	2.5	2.4	2.1	2.8	2.4	2.5	-0.2	2.5	2.3	2.2
Commuting to job workplace: Public transport	3.0	3.5	5.6	-2.0	-1.8	-2.4	-2.0	-2.3	-1.6	-1.5	-1.9	-1.8	-1.9	-1.9	-2.3	-2.0	-1.1	-0.0	-1.8	-2.2	-1.9
Worry (Nagel 2018)	2.9	6.2	11.1	-2.6	-2.6	-1.1	-2.4	-2.6	-2.4	-2.7	-2.6	-2.4	-2.4	-2.7	-2.1	-2.5	-3.3	-1.8	-2.6	-2.7	-2.6
Chronotype (morning person)	2.9	6.6	8.9	2.1	2.8	1.0	2.5	2.5	3.0	2.9	2.9	2.6	2.9	2.9	2.5	2.6	2.3	2.2	2.1	2.9	2.8
Impedance of arm (right)	2.9	13.7	19.4	-4.0	-4.1	-2.5	-3.7	-4.4	-4.4	-3.3	-3.9	-4.3	-4.3	-3.4	-3.7	-3.6	-3.6	-1.2	-3.9	-3.7	-3.3
Happiness	2.9	3.5	5.5	-1.7	-1.8	-1.4	-1.8	-1.7	-2.0	-2.1	-2.1	-1.9	-2.1	-1.9	-1.9	-1.7	-2.1	-1.2	-1.7	-2.3	-1.9
Arm predicted mass (right)	2.9	15.1	19.4	4.0	4.4	3.0	3.7	4.4	4.1	3.9	4.2	3.9	3.9	4.0	3.6	4.0	3.8	2.3	3.9	4.3	4.0
Deep venous thrombosis (DVT) (self-reported)	2.9	3.7	6.2	2.5	2.0	1.9	1.9	2.0	1.5	1.6	2.0	2.0	1.9	1.9	2.1	2.0	1.9	0.4	2.5	1.9	1.8
Cardiovascular Disease	2.8	9.2	14.1	2.6	3.4	1.3	2.7	3.1	3.5	3.2	3.6	2.9	3.4	3.3	2.7	3.8	2.6	1.8	2.5	3.7	3.4
Illnesses of siblings	2.8	4.0	8.0	-1.9	-2.3	-0.0	-2.1	-2.8	-1.8	-2.0	-2.2	-2.0	-2.0	-2.2	-2.1	-2.2	-2.1	0.3	-1.6	-2.2	-2.0
Supplements: Vitamin C	2.8	3.4	5.8	-2.0	-1.9	-1.1	-1.7	-2.3	-1.2	-1.9	-1.9	-1.3	-1.5	-2.2	-1.5	-2.0	-1.8	-1.8	-1.7	-2.4	-2.1
Neuroticism (Nagel 2018)	2.7	6.2	8.9	-2.6	-2.8	-2.3	-2.4	-2.6	-2.4	-2.8	-2.6	-2.4	-2.6	-2.6	-2.6	-2.3	-3.0	-1.6	-2.6	-2.2	-2.4
Neuroticism score	2.7	5.7	9.7	-2.5	-2.5	-1.7	-2.5	-2.3	-2.5	-2.7	-2.5	-2.6	-2.6	-2.4	-2.1	-2.1	-3.1	-1.7	-2.5	-2.3	-2.1
Arm fat-free mass (right)	2.7	14.0	17.9	3.9	4.2	2.6	3.6	4.2	3.9	3.7	4.1	3.7	3.7	3.9	3.5	3.9	3.7	2.0	3.8	4.1	3.9
Medication: Aspirin	2.7	3.6	6.4	1.3	2.1	-0.1	1.7	1.7	2.5	2.1	2.1	1.6	2.2	2.1	1.0	2.3	1.6	2.1	1.2	2.5	2.1
Breast cancer (self-reported)	2.6	3.2	5.7	1.2	1.8	0.4	1.9	2.0	1.9	2.3	2.0	1.2	1.8	2.2	1.1	2.4	2.1	-0.2	1.0	2.2	2.2
Ulcerative Colitis (UC)	2.5	4.7	7.2	2.4	2.3	0.6	2.2	2.7	1.5	2.1	2.4	2.4	2.2	2.3	1.8	2.2	2.5	1.8	2.2	2.3	2.4
Fasting Glucose	2.5	3.0	5.0	2.2	1.8	0.4	1.7	1.8	1.6	1.8	1.8	2.1	1.8	1.6	1.9	1.1	1.8	1.0	2.2	1.7	1.6
Qualifications: CSEs or equivalent	2.5	3.4	6.8	2.0	1.9	2.6	1.7	2.1	2.1	1.4	2.0	2.3	1.6	1.6	1.8	1.9	1.6	-0.1	1.9	1.7	1.4
Blood clot in the leg (DVT)	2.5	3.3	6.2	2.5	1.8	1.9	2.0	1.9	1.2	1.5	1.8	1.8	1.7	1.7	1.9	2.0	1.7	0.3	2.5	1.7	1.6
Pain type(s) experienced in last month: Hip pain	2.4	3.0	4.6	1.9	2.0	0.3	1.4	1.9	1.7	1.7	1.9	1.9	1.6	1.9	2.1	1.9	1.4	1.2	1.9	1.9	1.8
Alzheimer’s Disease (in mother)	2.3	2.7	4.1	-1.4	-1.7	-1.9	-1.9	-1.4	-1.9	-2.0	-1.7	-1.5	-2.0	-1.6	-1.1	-1.7	-1.4	-1.5	-1.4	-1.8	-1.6
Pack years adult smoking proportion	2.3	3.6	8.1	2.3	1.6	-0.8	1.7	2.3	1.5	1.4	1.9	2.2	1.9	1.9	2.9	1.9	1.2	1.7	2.2	1.9	1.7
Age at last live birth	2.3	3.3	7.0	-2.2	-1.5	0.2	-1.7	-2.1	-1.4	-1.9	-1.9	-1.9	-1.8	-1.9	-1.7	-1.7	-2.6	-0.3	-2.1	-2.1	-2.0
Whole body fat-free mass	2.3	13.1	16.3	3.8	4.0	3.4	3.5	3.9	3.6	3.6	3.9	3.5	3.5	3.8	3.3	3.7	3.6	1.7	3.6	4.0	3.9
Whole body water mass	2.3	13.3	16.6	3.8	4.1	3.4	3.5	4.0	3.7	3.6	3.9	3.5	3.6	3.8	3.4	3.8	3.6	1.8	3.7	4.0	3.9
Alzheimer’s Disease (including proxy)	2.2	3.2	5.8	-1.7	-1.7	-1.1	-2.1	-1.8	-2.0	-2.0	-1.9	-1.5	-2.0	-1.8	-1.0	-1.8	-1.4	-2.4	-1.7	-1.9	-1.8
Diabetes (self-reported)	2.2	3.4	4.4	1.7	1.8	1.7	1.9	1.8	1.9	1.9	2.0	1.9	2.0	1.9	1.7	2.1	2.0	0.4	1.7	1.8	2.1
Medication: Amlodipine	2.2	3.1	4.9	1.8	2.0	0.4	1.6	2.2	2.0	1.6	1.9	2.2	2.1	1.6	1.6	1.8	1.6	1.5	1.6	1.8	1.6
Diabetes diagnosed by doctor	2.2	3.6	4.7	1.6	1.9	1.8	1.9	1.9	2.2	1.9	2.1	1.9	2.1	1.9	2.0	2.0	2.1	0.8	1.6	2.1	2.1
Medication: Aspirin	2.2	2.9	5.8	1.0	1.9	-0.1	1.3	1.5	2.4	1.9	1.9	1.5	2.1	1.8	0.6	2.1	1.4	1.9	1.0	2.2	1.9
Neuroticism	2.1	5.0	6.2	-2.2	-2.5	-1.4	-2.3	-2.4	-2.2	-2.5	-2.4	-2.2	-2.3	-2.5	-1.9	-2.0	-2.3	-1.9	-2.1	-2.5	-2.4
Vitamin and mineral supplements	2.1	2.8	5.2	1.6	1.7	1.0	1.7	2.1	1.8	1.6	1.9	1.9	1.9	1.8	1.6	1.6	1.3	0.8	1.4	2.3	1.6
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	4.0	-1.7	-1.7	0.1	-1.5	-1.8	-1.2	-1.5	-1.6	-1.5	-1.6	-1.6	-2.0	-1.5	-1.2	-0.3	-1.6	-1.6	-1.3
Pack years of smoking	2.1	3.0	7.3	2.1	1.4	-1.0	1.6	2.1	1.2	1.3	1.7	2.0	1.7	1.7	2.7	1.8	1.1	1.7	2.1	1.7	1.5
Blood Eosinophil Count	2.0	15.3	28.3	-3.2	-4.2	-1.5	-4.1	-3.9	-3.4	-5.1	-4.4	-2.4	-3.4	-5.1	-3.6	-4.7	-4.0	1.4	-2.9	-5.0	-5.3
Type 2 Diabetes (T2D) (2018)	2.0	3.8	5.2	1.8	1.9	2.2	2.1	1.8	2.0	1.8	2.1	2.0	2.3	1.9	1.5	2.2	2.0	1.0	1.8	2.0	2.2
Serious illness, injury or assault to yourself	2.0	2.4	6.4	1.2	1.8	-0.2	1.2	1.5	1.9	1.4	1.8	1.6	1.9	1.5	0.9	1.6	1.0	2.5	1.2	1.6	1.5
Alzheimer’s Disease (in father)	1.9	2.1	3.6	-1.3	-1.6	0.4	-1.5	-1.6	-1.5	-1.8	-1.6	-1.2	-1.4	-1.7	-0.6	-1.4	-0.8	-1.9	-1.1	-1.8	-1.5
LDL Cholesterol	1.9	3.0	5.0	2.1	1.5	1.7	1.8	1.7	1.6	1.7	1.8	2.2	1.8	1.6	2.1	1.6	1.5	0.8	2.2	1.7	1.4
Neuroticism (2016)	1.9	2.8	4.0	-1.6	-1.9	-2.0	-1.5	-1.8	-1.8	-1.5	-1.9	-1.8	-1.8	-1.6	-1.6	-1.4	-1.3	-1.1	-1.6	-1.7	-1.5
Forced vital capacity (FVC)	1.9	7.5	11.0	-3.1	-2.5	-1.5	-3.3	-2.9	-2.2	-2.4	-2.8	-3.0	-2.9	-2.7	-3.0	-2.8	-2.8	-2.0	-3.1	-3.0	-2.5
Health satisfaction	1.9	2.5	3.8	1.7	1.7	0.2	1.7	1.6	0.9	1.6	1.5	1.4	1.5	1.8	1.8	1.9	1.9	0.7	1.7	1.7	1.7
Number of operations (self-reported)	1.9	2.9	5.8	1.9	1.4	1.5	1.8	1.7	2.0	1.3	1.7	2.4	2.2	1.2	1.7	1.7	1.8	0.5	2.0	1.3	1.1
Smoking Status	1.8	4.4	6.6	1.8	2.3	0.7	2.2	2.2	2.6	1.9	2.3	2.1	2.3	2.1	2.1	2.3	2.6	1.0	1.8	2.3	2.2
Taking other prescription medications	1.8	2.8	4.0	1.6	1.7	1.4	1.4	1.8	1.6	1.9	1.8	1.8	2.0	1.7	1.6	2.0	2.0	-0.4	1.6	1.6	1.6
Nervous feelings	1.7	3.1	6.2	-1.9	-1.7	-2.0	-1.7	-1.8	-1.7	-1.6	-1.8	-2.1	-1.8	-1.6	-1.6	-1.5	-2.5	-0.0	-1.9	-1.6	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	4.4	-2.0	-1.4	-1.1	-1.8	-1.3	-1.0	-1.4	-1.2	-1.7	-1.6	-1.4	-1.4	-0.9	-1.9	1.6	-2.1	-1.2	-1.1
Medication: Omeprazole	1.7	2.1	3.8	1.8	1.4	0.3	1.3	1.6	1.3	1.2	1.5	1.7	1.6	1.2	1.9	1.3	1.6	-1.4	1.8	1.1	1.1
Heart disease (siblings)	1.7	2.1	3.7	1.8	1.5	-0.9	1.8	1.9	1.2	0.7	1.2	1.7	1.6	1.2	1.4	1.3	1.9	-1.2	1.7	1.2	1.2
Supplements: Glucosamine	1.6	2.1	3.5	1.1	1.4	1.1	1.5	1.2	1.8	1.8	1.6	1.4	1.6	1.5	1.5	1.4	1.9	0.4	1.2	1.5	1.4
Miserableness	1.6	2.8	5.4	-2.1	-1.7	-1.3	-2.0	-1.6	-1.3	-1.8	-1.6	-2.0	-1.7	-1.6	-1.5	-1.3	-2.3	-0.5	-2.2	-1.5	-1.3
Systolic blood pressure, automated reading	1.5	4.5	8.7	1.8	2.3	1.2	1.7	2.6	2.9	1.7	2.6	2.7	2.6	2.1	2.0	1.9	2.3	0.2	1.7	2.3	1.8
Number of incorrect matches in round	1.5	2.4	5.3	1.5	2.0	0.4	1.5	2.3	1.6	2.0	1.8	1.2	1.5	1.9	1.7	1.8	1.1	0.3	1.1	1.7	1.4
Worry too long after embarrassment	1.5	2.6	4.3	-1.6	-1.5	-2.1	-1.6	-1.4	-1.6	-1.7	-1.6	-1.8	-1.7	-1.4	-1.6	-1.5	-1.7	-1.5	-1.7	-1.2	-1.3
Overall health rating	1.5	3.2	5.0	1.8	2.0	0.3	1.7	2.1	1.6	1.8	2.0	1.7	2.1	2.0	1.6	2.2	1.8	1.0	1.6	2.0	2.0
Hypertension (Self-reported)	1.5	4.2	6.8	1.8	2.3	-0.2	1.7	2.1	2.0	2.2	2.4	1.9	2.2	2.2	1.7	2.6	2.2	1.2	1.7	2.6	2.4
Ever had bowel cancer screening	1.5	1.7	2.7	-1.1	-1.4	-0.5	-1.1	-1.4	-1.6	-1.4	-1.6	-1.3	-1.5	-1.3	-1.4	-1.2	-0.9	-1.6	-1.0	-1.5	-1.5
Diabetes (mother)	1.4	1.7	3.7	0.9	1.4	1.9	1.0	1.6	1.9	1.3	1.5	1.9	1.7	1.0	0.8	1.1	1.3	-0.4	0.8	1.1	0.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.9	1.5	1.2	0.2	1.5	1.5	1.2	0.4	1.2	1.6	1.7	1.0	1.4	1.0	0.9	0.7	1.5	1.0	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	2.6	1.5	1.0	1.6	1.5	1.5	1.1	0.8	1.4	1.6	1.4	1.1	0.7	1.2	0.9	1.3	1.5	1.5	1.0
Guilty feelings	1.4	2.1	3.5	-1.6	-1.6	-1.9	-1.5	-1.5	-1.2	-1.3	-1.4	-1.4	-1.3	-1.5	-1.6	-1.2	-1.6	-0.9	-1.6	-1.3	-1.4
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	2.9	1.6	1.1	-0.2	1.1	1.4	1.3	1.1	1.4	1.6	1.6	1.0	1.7	1.2	1.7	-0.8	1.6	1.0	1.1
Ulcerative Colitis	1.3	1.8	3.2	1.1	1.7	-0.1	1.3	1.8	1.3	1.5	1.6	1.3	1.6	1.5	1.5	1.2	1.3	0.0	0.9	1.7	1.5
Lung FEV1/FVC ratio	1.3	6.6	11.9	2.5	2.3	3.5	2.7	2.8	2.6	2.6	3.0	2.7	2.5	2.6	2.3	2.6	2.2	0.5	2.3	3.0	2.7
Medication: Co-codamol	1.3	1.5	3.3	1.2	1.2	0.1	1.5	1.2	0.7	1.0	1.1	1.3	1.3	1.1	1.8	1.3	1.6	-1.4	1.2	1.1	1.1
Heart attack	1.3	1.7	4.3	1.4	1.2	0.1	1.4	1.1	1.3	1.2	1.2	1.2	1.1	1.2	1.3	1.4	1.3	2.1	1.5	1.3	1.2
Medication: Blood pressure	1.3	2.3	4.3	1.1	1.8	0.6	1.2	1.8	1.5	1.7	1.8	1.2	1.5	1.8	1.2	2.1	1.6	0.5	0.9	2.0	1.7
Average weekly beer plus cider intake	1.3	1.9	6.1	-1.3	-1.3	-0.4	-1.0	-1.2	-1.3	-1.7	-1.3	-1.2	-1.5	-1.5	-1.2	-1.3	-1.2	-2.5	-1.4	-1.2	-1.4
Depressed Affect (Nagel 2018)	1.2	2.6	3.6	-1.7	-1.8	-1.6	-1.6	-1.4	-1.6	-1.7	-1.5	-1.8	-1.8	-1.5	-1.9	-1.2	-1.9	-0.9	-1.9	-1.3	-1.3
Irritable Bowel Disease (IBD)	1.2	2.9	4.9	1.9	1.9	1.0	1.6	2.2	1.3	1.4	1.9	2.1	1.8	1.6	1.3	1.6	2.1	1.0	1.8	1.8	1.7
Supplements: Zinc	1.2	1.3	2.4	-0.9	-1.0	-1.4	-1.2	-1.1	-1.1	-1.1	-1.3	-1.1	-1.2	-1.1	-1.3	-1.2	-0.6	0.4	-0.9	-1.5	-1.1
Hearing difficulty/problems with background noise	1.2	1.9	3.3	1.2	1.4	0.4	1.3	1.5	1.4	1.8	1.5	1.0	1.0	1.6	1.4	1.6	1.6	1.0	1.1	1.7	1.7
Trunk predicted mass	1.2	6.6	8.9	2.8	3.0	2.3	2.6	2.7	2.4	2.6	2.7	2.3	2.3	2.8	2.3	2.7	2.7	1.0	2.7	2.9	2.9
Eye problems/disorders: None of the above	1.2	1.3	2.5	-1.2	-1.2	-0.3	-0.6	-1.6	-1.4	-1.2	-1.2	-1.3	-1.3	-1.2	-1.5	-0.9	-1.1	-0.7	-1.1	-1.0	-1.1
Knee pain experienced in last month	1.2	1.8	3.4	1.1	1.5	1.3	0.9	1.9	1.8	1.2	1.4	1.4	1.6	1.3	1.8	1.4	0.7	0.9	0.9	1.3	1.0
Heart attack/myocardial infarction (self-reported)	1.2	1.5	4.8	1.4	1.1	0.1	1.4	1.1	1.0	1.1	1.1	1.0	0.9	1.1	1.3	1.3	1.1	2.2	1.5	1.2	1.1
High blood pressure	1.1	3.1	5.2	1.4	2.0	-0.6	1.3	1.7	1.9	1.9	2.1	1.6	1.8	1.8	1.4	2.3	2.0	1.1	1.4	2.3	2.1
Had other major operations	1.1	1.3	2.6	1.0	1.0	-0.3	1.1	1.3	1.6	1.1	1.2	1.1	1.3	1.1	0.9	1.3	1.5	0.3	1.0	1.1	1.3
Trunk fat-free mass	1.1	6.1	8.3	2.6	2.9	2.4	2.5	2.6	2.3	2.5	2.6	2.2	2.2	2.6	2.2	2.6	2.5	1.0	2.6	2.7	2.7
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	5.6	-2.4	-1.8	-0.5	-2.3	-2.1	-1.1	-1.6	-1.9	-2.1	-1.9	-2.0	-2.1	-2.0	-2.1	-1.4	-2.4	-2.2	-1.8
Lung cancer (father)	1.1	1.3	2.2	1.2	1.3	0.5	1.1	1.0	0.5	1.1	1.1	0.9	0.8	1.2	1.2	1.2	1.3	1.1	1.2	1.5	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	3.0	-1.6	-1.2	-0.9	-1.5	-1.2	-1.3	-1.5	-1.2	-1.6	-1.5	-1.2	-1.2	-0.8	-1.7	1.4	-1.6	-1.0	-0.9
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	4.5	-1.5	-1.6	-2.1	-1.5	-1.6	-1.5	-1.4	-1.6	-1.5	-1.5	-1.5	-1.6	-1.1	-1.5	-0.1	-1.4	-1.6	-1.2
Forced vital capacity (FVC), Best measure	1.1	4.0	6.8	-2.4	-1.8	-0.9	-2.6	-2.1	-1.4	-1.6	-2.0	-2.4	-2.1	-1.9	-2.3	-2.0	-1.9	-1.3	-2.4	-2.1	-1.7
Mood swings	1.1	2.0	3.0	-1.5	-1.5	-1.2	-1.6	-1.4	-1.5	-1.3	-1.3	-1.6	-1.6	-1.3	-1.6	-1.2	-1.7	-1.0	-1.5	-1.3	-1.1
Long-standing illness, disability or infirmity	1.1	1.6	2.9	-1.1	-1.3	-1.7	-1.3	-1.0	-1.7	-1.1	-1.4	-1.5	-1.4	-1.1	-1.3	-0.9	-1.5	0.8	-1.2	-1.0	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	4.6	-1.7	-1.6	-1.9	-1.1	-1.4	-0.9	-0.7	-1.2	-1.5	-1.4	-1.1	-2.1	-1.0	-0.6	-1.4	-1.7	-0.8	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.6	1.0	1.0	1.9	1.1	0.9	1.1	1.0	1.2	1.0	1.2	1.0	1.0	1.3	0.9	0.9	1.1	1.1	1.2
Fractured/broken bones in last 5 years	1.1	1.5	2.8	-1.3	-1.3	-0.7	-1.3	-1.3	-0.5	-1.7	-1.1	-0.9	-0.9	-1.4	-1.4	-1.4	-1.3	0.8	-1.2	-1.3	-1.3
Ever depressed for a whole week	1.1	1.4	2.4	0.9	1.4	1.1	1.3	1.2	0.8	1.3	1.3	0.9	1.0	1.5	1.3	1.2	0.5	1.2	0.9	1.5	1.5
Cholesterol lowering medication	1.1	1.6	3.5	1.3	1.3	0.4	1.4	1.3	0.6	1.6	1.4	1.1	1.0	1.5	1.1	1.9	1.1	0.1	1.2	1.5	1.6
Bipolar Disorder (2011)	1.0	1.0	2.8	-1.3	-0.9	-1.7	-1.1	-1.1	0.1	-1.1	-0.9	-0.7	-0.5	-1.2	0.0	-1.1	-0.2	-0.9	-1.2	-0.9	-1.0
Systolic Blood Pressure	1.0	5.2	8.3	1.8	2.9	1.5	2.1	2.6	2.6	2.0	2.8	2.4	2.7	2.4	2.2	2.4	2.3	-0.3	1.6	2.5	2.3
Medication for hormone replacement therapy	1.0	1.2	1.7	1.2	1.0	0.4	1.3	1.1	0.9	1.2	1.1	1.1	1.0	1.3	0.9	1.2	1.2	0.7	1.2	1.0	1.2
Fed-up feelings	1.0	1.9	3.2	-1.6	-1.2	-1.5	-1.6	-1.1	-1.4	-1.4	-1.2	-1.8	-1.6	-1.1	-1.7	-1.0	-1.7	-0.2	-1.7	-1.0	-0.7
Number of children fathered	1.0	1.2	2.5	1.2	1.1	1.0	0.8	1.4	1.1	0.7	1.1	1.6	1.2	0.8	0.8	0.8	1.3	-1.3	1.2	0.8	0.5
Age at first live birth	1.0	1.8	3.3	-1.7	-1.0	-0.2	-1.3	-1.7	-1.2	-1.4	-1.4	-1.6	-1.5	-1.2	-1.1	-1.2	-1.8	-0.3	-1.5	-1.4	-1.2
Chest pain or discomfort	1.0	1.4	3.0	-1.2	-1.2	-1.7	-1.1	-1.4	-1.3	-1.2	-1.1	-1.6	-1.5	-1.0	-1.1	-0.9	-1.3	0.2	-1.1	-0.7	-0.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.8	1.0	1.3	-0.7	1.1	1.2	1.6	1.3	1.1	1.1	1.2	1.0	0.8	0.9	1.7	-0.3	1.1	0.7	0.9
Ever taken oral contraceptive pill	1.0	1.2	2.9	-1.0	-1.2	-1.0	-0.6	-1.4	-1.6	-0.9	-1.3	-1.7	-1.4	-0.7	-1.1	-0.5	-0.4	-0.9	-0.9	-0.9	-0.5
Vascular/heart problems diagnosed by doctor	1.0	2.7	4.5	-1.3	-1.9	1.1	-1.3	-1.5	-1.7	-1.7	-1.9	-1.4	-1.7	-1.7	-1.1	-2.1	-1.9	-1.4	-1.3	-2.1	-2.0
Alcohol drinker status: Previous	1.0	1.1	10.7	0.9	0.8	-0.1	1.2	0.7	0.5	0.4	0.7	1.1	0.8	0.4	1.1	0.5	0.2	3.3	1.0	0.6	0.5
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.8	1.0	1.3	-0.6	1.0	1.2	0.7	1.1	1.0	0.4	0.7	1.2	1.1	1.3	0.9	1.0	0.7	1.3	1.2
Hypothyroidism (self reported)	0.9	2.2	3.2	-1.4	-1.8	-1.4	-1.5	-1.7	-1.6	-1.6	-1.6	-1.3	-1.6	-1.6	-1.4	-1.1	-1.6	0.5	-1.2	-1.6	-1.4
Diabetes (father)	0.9	1.1	3.8	1.2	0.8	0.8	1.1	1.0	0.5	1.2	0.8	0.8	0.9	1.0	1.0	1.0	1.1	2.0	1.2	0.9	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	4.1	-0.7	-1.2	-0.7	-1.3	-1.0	-1.5	-1.4	-1.2	-0.9	-1.5	-1.2	-0.6	-1.1	-2.0	0.2	-0.6	-1.3	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	3.3	-1.4	-1.0	-1.8	-1.2	-1.1	-1.1	-1.1	-1.1	-1.8	-1.3	-0.7	-0.9	-0.5	-1.2	-1.1	-1.5	-0.9	-0.6
Pulse rate, automated reading	0.9	3.0	6.2	1.4	2.1	0.9	1.3	1.9	1.7	2.0	2.0	1.4	1.6	2.0	2.5	1.6	1.4	-0.1	1.3	2.2	2.1
Eye problems/disorders: Cataract	0.9	1.1	2.0	1.2	1.0	1.0	0.7	1.2	0.7	1.3	1.0	0.9	1.0	1.2	1.4	1.0	0.6	0.3	1.2	1.0	1.1
Medication: Bendroflumethiazide	0.9	1.4	2.5	1.0	1.1	-1.3	0.8	1.3	1.0	1.4	1.3	0.9	1.1	1.5	0.8	1.6	1.3	0.5	1.0	1.5	1.6
Ever smoked	0.9	1.5	4.2	0.5	1.4	-0.4	1.2	1.1	2.1	1.2	1.4	1.2	1.4	1.3	0.6	1.3	1.8	0.2	0.5	1.3	1.3
HbA1C	0.8	0.9	2.4	-0.2	1.4	-0.5	0.4	1.6	1.4	1.2	0.8	-0.7	0.3	1.1	0.5	1.2	0.7	0.2	-0.5	1.1	0.9
Average weekly spirits intake	0.8	1.0	2.5	1.6	0.9	-0.6	1.0	1.1	0.1	0.4	1.0	1.2	0.9	0.8	1.4	0.9	0.7	1.1	1.6	1.0	0.7
Hand grip strength (right)	0.8	2.2	5.4	1.4	1.6	1.3	1.2	1.5	2.2	1.0	1.6	2.3	2.3	0.9	1.9	0.9	1.2	-0.8	1.5	0.9	0.8
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.4	0.6	1.1	0.7	0.9	0.8	0.8	1.4	1.0	0.4	0.8	1.2	0.4	1.1	1.6	-0.8	0.5	1.1	1.2
Financial situation satisfaction	0.8	1.0	1.9	0.7	1.2	0.9	0.9	1.3	1.2	1.2	1.1	0.8	0.9	1.1	1.0	1.4	0.9	0.3	0.6	1.1	1.1
Medication: Lisinopril	0.8	1.1	2.1	1.3	0.7	0.6	0.7	1.1	1.2	0.9	1.1	1.4	1.2	0.8	1.4	1.1	0.7	1.0	1.3	1.0	0.7
Lung FVC	0.7	3.6	5.5	-2.1	-1.7	-1.6	-2.3	-1.9	-1.2	-1.3	-2.1	-1.9	-1.8	-1.9	-1.5	-2.1	-2.1	-1.3	-2.1	-2.3	-2.1
Age when periods started (menarche)	0.7	1.6	4.3	-1.2	-1.5	-1.0	-1.2	-1.6	-2.1	-0.7	-1.3	-1.7	-1.8	-0.8	-1.0	-1.1	-1.1	-1.0	-1.1	-0.8	-0.6
Worrier / anxious feelings	0.7	1.4	3.6	-1.3	-1.3	-1.1	-1.5	-1.0	-0.7	-1.2	-1.1	-1.0	-1.0	-1.2	-0.9	-1.1	-1.9	-0.7	-1.3	-1.2	-1.1
Prospective memory result	0.7	0.8	1.6	1.2	0.8	-0.1	0.9	1.1	0.4	0.8	0.8	0.8	0.7	0.8	0.9	0.9	1.1	1.3	1.2	1.0	0.7
Pulse wave peak to peak time	0.7	0.8	1.5	-0.8	-1.1	-0.4	-0.7	-1.2	-0.9	-0.9	-0.9	-0.7	-0.9	-1.1	-0.8	-1.2	-0.6	-1.0	-0.6	-0.9	-1.0
Angina (self-reported)	0.7	0.9	2.2	0.7	1.2	-0.8	1.3	1.0	0.6	1.0	0.9	0.2	0.5	1.0	0.7	1.5	0.8	-0.1	0.6	1.4	1.2
Heart disease (mother)	0.7	0.8	1.9	0.7	1.0	0.4	0.5	1.2	1.4	0.8	1.1	1.3	1.1	0.7	1.4	0.9	0.5	0.3	0.6	0.6	0.5
Commuting to job workplace: Walk	0.7	0.8	2.2	-1.1	-0.6	-1.5	-1.1	-0.8	-0.4	-0.5	-0.6	-1.0	-0.8	-0.5	-1.1	-0.8	-0.4	1.4	-1.1	-0.5	-0.3
Wears glasses or contact lenses	0.7	0.9	2.6	0.5	1.3	-0.9	0.4	1.1	1.4	0.7	0.9	0.5	0.8	0.8	0.6	1.0	1.6	-0.9	0.4	0.8	0.9
Eye problems/disorders: Glaucoma	0.7	0.8	1.3	0.9	1.0	0.6	0.5	0.8	0.7	1.0	1.0	0.8	0.7	1.0	0.8	0.9	1.1	1.0	0.9	1.0	1.1
Age started oral contraceptive pill	0.7	0.9	1.7	1.0	0.5	0.8	0.9	0.9	0.8	1.2	0.9	0.9	0.8	1.1	1.3	0.9	1.2	-1.0	1.0	0.8	0.7
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.4	0.3	0.8	1.4	0.3	0.8	1.6	0.6	0.8	0.9	1.0	0.5	0.7	0.6	0.8	-0.2	0.2	0.7	0.6
Severe depression (siblings)	0.6	0.7	1.4	-0.6	-0.8	-1.2	-1.2	-1.0	-1.1	-0.5	-0.9	-1.1	-1.2	-0.7	-0.6	-0.8	-0.7	0.2	-0.5	-0.8	-0.6
Stomach or abdominal pain in last month	0.6	0.8	10.4	-0.2	0.3	-0.6	-0.1	-0.0	-0.4	0.6	0.2	-0.8	-0.6	0.6	-0.1	0.8	-0.2	3.2	-0.2	0.5	0.8
Sitting height	0.6	3.9	6.8	-2.4	-2.2	-1.1	-2.1	-2.3	-1.7	-1.6	-2.0	-2.4	-2.4	-1.7	-2.6	-1.9	-2.0	-0.1	-2.4	-1.6	-1.6
Financial difficulties in last 2 years	0.6	0.7	2.1	0.9	0.7	1.5	0.8	1.1	0.9	0.2	0.8	1.2	0.9	0.4	1.2	0.7	0.3	0.9	0.9	0.6	0.4
Time employed in main current job	0.6	0.7	2.3	-0.4	-0.7	0.3	-0.5	-0.8	-0.5	-1.2	-0.7	-0.1	-0.5	-1.2	-0.2	-0.9	-0.9	-1.5	-0.2	-1.2	-1.3
Alcohol intake versus 10 years previously	0.6	0.8	3.0	0.7	0.6	1.7	0.5	0.9	1.6	0.5	0.8	1.7	1.5	0.4	0.4	0.4	0.5	0.2	0.8	0.2	0.1
Depression (self-reported)	0.6	0.7	2.3	-0.5	-0.9	0.2	-0.6	-0.8	-1.5	-0.9	-0.8	-1.3	-1.0	-0.7	0.2	-0.1	-1.3	-1.2	-0.5	-0.3	-0.4
Peak expiratory flow (PEF)	0.6	1.4	2.9	-1.7	-1.0	-0.3	-1.4	-1.5	-0.1	-0.8	-1.0	-1.2	-0.9	-1.3	-1.6	-1.3	-0.8	-0.7	-1.6	-1.5	-1.1
Ever highly irritable/argumentative for 2 days	0.6	0.8	1.9	0.5	1.1	-0.5	0.9	0.8	1.4	0.5	1.0	1.4	1.4	0.6	0.3	0.3	0.9	1.3	0.5	0.7	0.4
Headache pain in last month	0.6	1.0	1.6	1.1	1.1	0.3	0.8	1.3	1.1	0.9	1.0	1.1	0.9	0.9	1.0	1.0	0.9	0.6	1.1	0.9	1.0
Glaucoma (self-reported)	0.6	0.7	1.6	0.7	1.0	0.1	0.6	0.7	0.6	1.3	0.9	0.5	0.5	1.2	0.6	1.1	1.2	0.5	0.8	1.0	1.1
Birth weight	0.6	1.3	2.5	0.9	1.2	1.2	0.7	1.2	1.1	1.4	1.3	1.1	1.1	1.2	1.6	1.2	0.5	0.4	0.8	1.4	1.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.5	0.7	0.9	0.8	0.7	1.2	0.3	0.6	0.9	0.5	0.6	1.0	0.4	1.1	0.8	-0.0	0.5	1.1	1.0
Exposure to tobacco smoke outside home	0.6	0.8	1.9	-0.8	-0.7	-1.2	-0.8	-0.7	-1.4	-1.0	-1.0	-1.2	-1.2	-0.9	-0.9	-0.5	-0.5	0.2	-0.9	-0.6	-0.7
Had major operations	0.6	0.7	1.9	1.0	0.8	0.9	0.7	0.6	0.6	0.8	0.7	1.4	1.0	0.5	1.2	0.8	0.5	0.9	1.1	0.7	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.1	2.1	-1.4	-1.1	-0.9	-1.0	-1.2	-1.1	-0.9	-0.9	-1.4	-1.2	-0.9	-1.4	-1.0	-0.9	-0.2	-1.4	-0.8	-0.6
Loneliness, isolation	0.6	0.9	1.6	-0.3	-0.9	-1.3	-0.4	-0.8	-1.2	-1.3	-0.9	-0.4	-0.9	-1.1	-0.6	-0.7	-1.3	0.8	-0.2	-1.2	-1.1
Illnesses of father: None of the above (group 1)	0.6	0.8	1.8	1.0	0.9	-0.2	0.9	0.9	0.9	0.8	1.1	1.4	0.9	0.8	0.9	0.9	1.0	-0.4	0.9	0.9	0.7
Average weekly champagne plus white wine intake	0.6	0.8	2.0	-1.1	-0.8	-1.2	-1.0	-1.0	-0.8	-0.2	-1.0	-1.4	-1.3	-0.5	-1.0	-0.6	-0.2	0.1	-1.1	-0.6	-0.6
Hearing aid user	0.6	0.7	1.9	-0.5	-0.8	0.3	-0.7	-0.7	-1.0	-1.1	-1.0	-0.2	-0.7	-1.3	-0.6	-0.9	-0.8	-0.3	-0.4	-1.2	-1.4
Basal cell carcinoma (self-reported)	0.6	0.7	1.5	-0.6	-0.8	0.1	-0.8	-0.6	-0.8	-1.2	-1.0	-0.4	-0.7	-0.9	-1.0	-0.9	-0.9	0.0	-0.6	-1.0	-1.0
Mean Putamen Volume	0.5	0.5	1.5	0.5	0.1	-0.4	0.9	0.5	1.0	0.4	0.7	1.0	1.2	0.5	1.2	0.6	0.1	0.7	0.6	0.7	0.6
Blood White Count	0.5	3.7	15.8	1.6	2.0	0.5	1.6	1.6	1.9	2.0	1.9	1.6	1.9	1.8	1.1	1.7	2.2	4.0	1.5	1.7	1.7
Alcohol usually taken with meals	0.5	0.8	1.4	-0.9	-0.9	0.1	-1.1	-1.2	-0.7	-0.6	-1.0	-1.1	-1.1	-0.8	-1.1	-1.2	0.0	-0.3	-0.9	-1.1	-0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.6	0.6	0.6	0.2	0.6	0.5	-0.0	0.8	0.7	0.2	0.4	1.0	0.4	0.8	0.3	1.9	0.6	1.0	1.1
Back pain experienced in last month	0.5	0.8	2.2	0.6	0.8	0.0	0.8	0.9	0.8	0.9	1.0	0.4	0.6	1.0	1.5	1.1	0.7	0.5	0.5	1.1	1.1
Osteoarthritis (self-reported)	0.5	0.7	1.1	1.0	0.6	0.3	1.0	0.9	0.3	1.0	0.7	0.8	0.7	0.9	0.7	0.9	1.0	0.7	1.0	0.7	0.7
Number of self-reported non-cancer illnesses	0.5	0.9	2.3	0.8	1.1	0.2	0.7	1.1	1.0	1.0	1.2	0.9	1.2	1.1	0.5	1.5	0.9	0.3	0.7	1.1	1.0
Alcohol drinker status: Never	0.5	0.6	1.9	-0.4	-0.9	0.2	-0.9	-0.9	-1.1	-0.6	-0.7	-0.6	-1.1	-0.8	0.1	-0.7	-1.4	-1.1	-0.4	-0.8	-0.7
Breast Cancer	0.4	0.9	2.0	-1.2	-1.3	-1.0	-0.8	-1.0	-0.9	-0.7	-0.9	-1.4	-1.1	-0.4	-1.3	-0.7	-0.4	-0.1	-1.2	-0.4	-0.3
Rheumatoid Arthritis	0.4	0.6	5.6	0.4	0.3	0.7	0.3	0.5	0.5	0.9	0.7	0.4	0.6	0.7	-0.1	0.4	0.3	2.4	0.4	0.7	0.6
Ever had hysterectomy (womb removed)	0.4	0.4	0.7	0.6	0.8	-0.0	0.3	0.8	0.5	0.6	0.7	0.6	0.7	0.6	0.8	0.7	0.5	0.8	0.5	0.8	0.6
Angina	0.4	0.6	1.7	0.4	1.0	-0.8	1.1	0.8	0.3	0.8	0.7	-0.1	0.2	0.8	0.4	1.3	0.5	-0.2	0.3	1.1	1.0
Average weekly fortified wine intake	0.4	0.4	3.6	0.1	-0.1	0.0	0.3	-0.5	-1.1	0.5	-0.1	-0.6	-0.6	0.2	1.1	0.1	-0.2	-1.9	0.2	0.2	0.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	3.3	0.8	-0.3	0.4	-0.3	-0.3	-0.9	-0.4	-0.4	0.4	-0.5	-0.3	1.1	-0.3	-0.2	-1.8	1.0	-0.6	-0.4
Medication: Ramipril	0.4	0.5	1.1	1.0	0.6	0.2	0.8	0.7	-0.2	0.6	0.7	0.9	0.6	0.8	0.9	0.6	0.5	0.2	1.0	0.9	0.8
Standing height	0.4	4.0	8.5	-2.3	-2.1	-1.3	-2.0	-2.4	-2.2	-1.6	-2.0	-2.9	-2.7	-1.6	-2.3	-1.6	-1.6	-0.5	-2.3	-1.6	-1.3
Gout (self-reported)	0.4	0.5	1.6	-1.0	-0.7	-0.2	-0.7	-0.8	-0.2	-0.4	-0.6	-0.8	-0.8	-0.7	-1.3	-0.7	-0.0	-0.6	-0.9	-0.8	-0.6
Illnesses of father: Heart disease	0.4	0.6	1.1	0.9	0.6	-0.2	0.8	0.9	0.3	1.0	0.6	0.4	0.4	0.9	0.7	1.0	0.7	1.0	0.8	1.0	1.0
Mineral and other dietary supplements	0.4	0.6	2.2	-0.6	-0.7	-1.1	-0.4	-0.2	-0.6	-1.4	-0.6	-0.4	-0.5	-0.9	-0.4	-0.4	-1.5	-0.0	-0.7	-0.4	-0.7
Osteoporosis (self-reported)	0.4	0.5	1.2	0.6	0.4	0.7	0.6	0.9	0.7	0.3	0.6	0.4	1.0	0.6	0.8	0.9	0.4	-1.1	0.5	0.6	0.6
Supplements: Calcium	0.4	0.4	1.8	-0.3	-0.3	1.0	-0.3	-0.7	-1.3	-0.5	-0.7	-1.0	-1.0	-0.2	-0.1	0.2	-0.7	0.6	-0.2	-0.5	-0.2
Major Depression (MDD)	0.3	0.3	0.9	-0.9	-0.0	-0.2	-0.7	-0.4	0.6	0.1	-0.1	-0.9	-0.1	-0.0	-0.8	-0.3	-0.9	0.9	-0.9	0.1	0.1
Prostate Cancer	0.3	0.4	1.7	-0.8	-0.2	-0.7	-0.6	-0.4	0.6	0.7	0.2	-0.8	0.1	0.3	-0.7	0.3	-0.3	1.3	-0.9	0.8	0.5
Age at First Birth	0.3	0.4	3.3	-0.0	-0.4	0.4	-0.3	-0.8	-0.1	-0.7	-0.4	0.2	0.2	-0.6	0.4	-0.5	-0.9	-1.8	0.1	-0.7	-0.5
Crohns Disease (2012)	0.3	0.5	1.3	0.3	0.9	0.4	0.7	0.7	1.1	0.4	0.6	0.8	1.1	0.4	0.8	0.7	0.8	-1.1	0.3	0.2	0.4
Lupus	0.3	0.4	6.4	-0.3	-0.2	2.5	-0.2	0.1	-0.2	-0.4	-0.3	-0.4	-0.2	-0.0	-0.1	0.2	-0.6	0.5	-0.3	-0.3	0.1
Height	0.3	6.5	11.5	-2.9	-2.6	-1.4	-2.6	-2.8	-2.7	-2.2	-2.5	-3.4	-3.2	-2.1	-2.8	-2.1	-2.2	-2.4	-2.9	-2.2	-1.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.3	-0.6	-0.9	-1.5	-0.8	-0.5	-0.5	-0.5	-0.5	-0.3	-0.5	-0.6	-0.3	-0.3	-0.3	0.3	-0.5	-0.5	-0.6
Relative age voice broke	0.3	0.4	1.5	-1.2	-0.2	-0.7	-0.5	-0.7	0.8	0.3	-0.2	-0.2	0.4	-0.4	-0.6	-0.2	0.1	-1.2	-1.2	-0.2	-0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.8	0.7	0.6	-0.2	0.8	0.6	-0.1	0.5	0.4	0.6	0.4	0.4	0.6	0.6	0.6	0.9	0.7	0.5	0.4
Multivitamins +/- minerals	0.3	0.3	1.6	-0.1	-0.6	-0.2	-0.3	-0.8	-0.8	-0.4	-0.7	-0.5	-0.8	-0.6	-0.3	-0.4	-0.2	-0.2	0.1	-1.3	-0.6
Had menopause	0.3	0.4	1.2	-0.5	-0.8	0.2	-1.1	-0.5	-0.1	-0.5	-0.6	-0.3	-0.4	-0.7	-0.3	-0.7	-0.3	-1.1	-0.4	-1.0	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.9	0.9	-0.2	-1.1	0.4	0.4	-1.0	-0.2	-0.2	0.2	-0.5	0.1	0.1	-0.2	-0.3	1.4	0.8	0.1	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	2.1	-1.4	-0.8	0.4	-1.4	-1.1	-0.2	-0.6	-0.8	-1.2	-0.8	-1.0	-1.3	-1.0	-1.2	-0.4	-1.4	-1.1	-0.8
Pulse wave Arterial Stiffness index	0.3	0.4	1.0	0.5	0.7	0.0	0.4	0.8	0.6	0.7	0.6	0.4	0.5	0.8	0.4	0.9	0.3	1.0	0.3	0.6	0.8
Exposure to tobacco smoke at home	0.3	0.3	1.2	-0.8	-0.0	-0.3	-0.7	-0.0	0.1	-0.5	-0.3	-0.2	-0.2	-0.4	-0.3	-0.4	-1.1	-0.9	-0.9	-0.2	-0.6
High blood pressure (siblings)	0.3	0.4	1.4	0.4	0.8	0.3	0.5	1.2	0.7	0.6	0.8	0.5	0.5	0.7	0.6	0.6	0.5	0.5	0.1	0.8	0.6
Wheeze or whistling in the chest in last year	0.3	0.5	4.0	-0.4	-0.3	-2.0	-0.7	-0.4	-0.3	-0.7	-0.6	-0.3	-0.5	-0.6	-0.1	-0.7	-0.7	-0.2	-0.4	-0.8	-0.7
Shortness of breath walking on level ground	0.3	0.3	2.0	-0.5	0.3	-1.4	-0.1	0.1	0.3	0.3	0.0	-0.7	0.1	0.3	-0.6	0.6	0.4	1.0	-0.7	0.3	0.3
Medication: Ibuprofen	0.3	0.3	1.5	1.2	-0.0	-0.8	0.5	0.5	-0.7	0.1	0.1	0.6	-0.2	0.3	0.4	0.1	-0.1	0.9	1.2	0.2	0.4
Leg pain on walking	0.3	0.3	1.9	-0.7	-0.4	-1.4	-0.4	-0.3	-0.4	0.3	-0.3	-0.9	-0.6	0.2	-0.5	0.0	-0.5	-0.2	-0.9	0.2	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.3	-0.1	-0.2	0.9	-0.4	-0.3	0.1	-1.0	-0.5	0.3	0.3	-0.8	0.1	-1.2	-1.0	0.4	-0.1	-0.8	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.2	-0.6	-0.5	-0.3	-0.6	-0.5	-0.2	-0.4	-0.5	-0.7	-0.6	-0.5	-0.8	-0.4	-0.5	-1.1	-0.7	-0.7	-0.6
Qualifications: nursing, teaching	0.3	0.4	3.3	-0.5	-0.6	0.1	-0.3	-1.0	-0.4	-0.2	-0.6	-0.5	-0.4	-0.6	-0.6	-0.1	-0.5	1.8	-0.2	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.8	0.6	1.0	1.0	0.3	1.1	1.1	1.1	0.9	0.8	1.1	0.8	1.3	0.8	0.2	0.5	0.4	0.6	0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.5	0.3	0.5	-0.9	0.4	0.7	-0.2	0.6	0.3	-0.1	-0.2	0.5	0.2	0.4	0.4	1.6	0.1	0.5	0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	3.7	0.2	0.2	1.9	0.0	-0.1	0.7	1.1	0.4	0.4	0.2	0.4	-0.3	-0.0	1.3	-0.4	0.4	0.1	0.2
Commuting to job workplace: Cycle	0.3	0.3	3.1	-0.2	-0.5	0.7	-0.3	-0.5	-0.4	-0.3	-0.4	-0.0	-0.2	-0.3	-0.3	-0.2	-0.6	1.8	-0.1	-0.4	-0.5
Pain experienced in last month	0.3	0.5	1.3	-0.4	-0.8	-0.8	-0.4	-1.0	-0.7	-0.6	-0.6	-0.4	-0.6	-0.8	-1.0	-0.9	-0.3	-1.1	-0.3	-0.8	-0.8
Schizophrenia vs Biploar Disorder	0.2	0.2	1.7	-0.2	-0.2	-0.9	-0.0	-0.4	0.1	0.1	-0.1	-0.5	0.0	-0.1	-0.6	0.2	-0.9	1.3	-0.1	-0.1	-0.0
Crohns Disease (2017)	0.2	0.4	1.0	0.7	0.6	0.8	0.5	0.7	0.6	0.3	0.6	1.0	0.7	0.4	0.5	0.6	0.9	-0.1	0.8	0.5	0.4
Ovarian Cancer	0.2	0.3	1.1	0.4	0.3	-0.3	0.9	0.2	-0.4	-0.1	0.2	-0.2	0.0	0.5	0.2	0.8	1.1	0.3	0.4	0.7	0.8
Tanning	0.2	1.9	4.6	-1.8	-1.0	-2.1	-1.8	-1.4	-1.1	-0.9	-1.3	-1.8	-1.4	-0.9	-1.8	-1.1	-0.8	0.0	-1.9	-0.9	-0.9
Sensitivity / hurt feelings	0.2	0.4	1.0	-0.5	-0.2	-0.5	-0.2	-0.3	-1.0	-0.7	-0.6	-0.8	-0.9	-0.4	-0.6	-0.4	-0.8	-0.8	-0.6	-0.5	-0.2
Townsend deprivation index at recruitment	0.2	0.3	0.9	0.7	0.8	-0.9	0.6	0.6	0.2	0.2	0.4	0.6	0.5	0.3	0.9	0.3	0.2	-0.2	0.6	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	3.2	0.2	0.4	-0.4	0.2	0.1	0.2	0.4	0.4	-0.1	0.1	0.6	0.4	0.6	0.9	1.8	0.3	0.8	1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.9	-0.3	-0.4	1.0	-0.7	-0.3	0.2	-0.1	-0.3	-0.3	-0.2	-0.3	-0.7	-0.3	-0.8	0.8	-0.3	-0.5	-0.4
Chronic bronchitis/emphysema (father)	0.2	0.3	0.7	0.0	0.7	0.8	-0.1	0.8	0.8	0.3	0.5	0.2	0.4	0.6	0.3	0.4	0.1	0.4	-0.1	0.6	0.7
Falls in the last year	0.2	0.3	1.1	-0.2	-0.5	0.5	-0.7	-0.2	0.0	-1.0	-0.4	0.3	0.1	-0.9	0.4	-0.5	-0.6	0.1	-0.2	-0.7	-0.9
Pulse rate	0.2	0.4	0.9	0.3	0.8	0.7	0.0	0.6	0.9	0.5	0.6	0.5	0.7	0.7	1.0	0.2	0.4	-0.9	0.1	0.6	0.7
Breastfed as a baby	0.2	0.2	0.7	-0.1	0.5	0.0	0.5	-0.0	-0.3	0.4	0.2	-0.4	-0.1	0.5	0.4	0.6	0.8	-0.3	-0.1	0.6	0.8
Hair/balding pattern: Pattern 4	0.2	0.5	1.8	-0.7	-0.6	-0.2	-0.8	-0.9	-1.1	-0.4	-0.5	-1.1	-1.4	-0.3	-0.4	-0.5	-0.6	0.2	-0.6	-0.2	-0.3
Loud music exposure frequency	0.2	0.2	0.7	-0.6	-0.2	-0.7	-0.5	-0.3	-0.0	0.4	-0.3	-0.5	-0.4	-0.2	-0.8	-0.2	-0.5	-0.0	-0.6	-0.5	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.8	0.5	0.5	-0.9	0.1	-0.1	0.2	0.6	0.3	0.7	0.6	0.2	0.4	0.4	0.5	-0.4	0.7	0.0	0.1
Number of full brothers	0.2	0.3	1.6	0.6	0.6	-0.4	0.5	0.2	0.4	0.2	0.4	0.4	0.7	0.2	0.7	0.5	0.0	-1.3	0.7	0.2	0.3
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	-0.8	0.1	-0.6	-0.6	-0.1	0.4	0.1	-0.1	-0.5	-0.1	-0.0	-0.8	-0.3	0.3	-0.5	-1.0	-0.2	-0.1
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.4	0.3	0.0	-0.1	0.5	0.6	0.5	0.3	0.8	0.4	0.1	0.5	0.4	0.2	-0.8	0.3	-0.0	-0.2
Medication: Seretide 50 evohaler	0.2	0.3	0.9	-0.1	-0.5	-1.0	-0.7	-0.2	-0.9	-0.0	-0.6	-0.6	-0.8	-0.0	-0.3	0.0	-0.6	0.3	-0.2	-0.4	-0.2
Mean time to correctly identify matches	0.2	0.3	2.7	-0.3	-0.4	-0.7	-0.1	-0.5	0.0	-0.1	-0.4	-0.1	-0.2	-0.6	-0.0	-0.3	0.0	-1.6	-0.3	-0.6	-0.8
Illnesses of siblings: Diabetes	0.2	0.2	1.3	0.2	0.5	0.1	0.1	0.6	0.8	0.8	0.4	0.6	0.5	0.4	0.2	0.4	0.2	1.1	0.1	0.4	0.1
Medication: Gliclazide	0.2	0.3	0.9	-0.0	0.4	1.0	0.2	0.2	0.6	0.4	0.5	0.5	0.3	0.3	-0.3	0.7	0.9	0.4	0.0	0.4	0.6
Smoking status: Current	0.2	0.4	2.4	-0.4	-0.3	-1.5	-0.5	-0.3	-0.2	-1.1	-0.3	-0.2	-0.2	-0.5	-0.1	-0.5	-0.5	0.9	-0.4	-0.3	-0.4
Illnesses of father: High blood pressure	0.2	0.2	2.5	-0.2	-0.4	0.3	0.1	-0.3	-0.6	-0.3	-0.2	-0.5	-0.2	-0.1	-0.3	-0.0	-0.3	1.6	-0.1	-0.1	-0.0
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.8	-0.7	-0.1	-1.4	-0.1	-0.4	0.2	-0.2	-0.2	-0.5	-0.1	-0.3	-0.7	-0.2	-0.0	0.9	-0.7	-0.1	-0.3
Reaction Time	0.1	0.1	1.3	0.1	-0.0	-0.4	0.1	-0.1	0.1	-0.2	-0.1	0.2	-0.0	-0.2	-0.4	-0.2	-0.4	-1.1	0.1	-0.2	-0.4
HDL Cholesterol	0.1	0.1	1.3	0.2	0.5	-1.1	0.4	-0.2	0.1	-0.1	0.1	0.3	0.4	0.1	0.3	0.4	0.3	0.3	0.3	-0.0	0.0
Blood Red Count	0.1	0.7	2.2	-0.5	0.9	-0.2	0.2	-0.1	0.4	1.5	0.6	-0.8	-0.2	1.0	-0.4	1.2	0.6	1.1	-0.7	1.2	1.0
Hand grip strength (left)	0.1	0.3	1.3	0.1	0.6	0.6	0.0	0.4	1.2	0.0	0.3	1.1	1.0	-0.2	0.3	-0.1	0.0	-0.8	0.1	-0.1	-0.5
Hearing difficulty/problems: Yes	0.1	0.1	0.8	0.2	0.5	-0.4	0.0	0.4	0.0	0.1	0.2	0.0	-0.2	0.1	-0.2	0.2	0.4	0.9	0.1	0.2	0.3
Relative age of first facial hair	0.1	0.2	0.8	-0.7	-0.2	-0.5	0.0	-0.4	-0.1	0.2	-0.4	-0.5	-0.2	-0.0	-0.9	-0.2	0.2	0.4	-0.7	-0.1	-0.2
Current tobacco smoking	0.1	0.2	1.7	0.2	0.1	-1.3	0.0	0.3	0.2	-0.6	0.2	0.4	0.3	-0.0	0.4	-0.2	-0.0	1.0	0.2	0.1	0.0
Medication: Levothyroxine sodium	0.1	0.2	1.3	-0.3	-0.6	-1.2	-0.2	-0.3	-0.6	-0.5	-0.6	-0.5	-0.6	-0.4	-0.2	-0.1	-0.5	0.1	-0.3	-0.6	-0.3
Hair/balding pattern: Pattern 2	0.1	0.2	1.3	0.4	0.5	-0.1	-0.1	0.5	-0.3	0.4	0.2	0.2	-0.1	0.4	-0.2	0.5	0.5	-1.1	0.3	0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	-0.6	-0.4	-0.5	-0.6	-0.5	-0.1	-0.5	-0.5	-0.6	-0.3	-0.3	-0.8	-0.4	0.2	0.6	-0.5	-0.2	-0.1
Mouth/teeth dental problems	0.1	0.1	0.7	0.4	-0.1	0.6	0.2	-0.2	-0.3	-0.0	-0.1	0.0	-0.1	-0.1	0.3	-0.2	-0.4	0.8	0.5	-0.3	-0.2
Pain all over the body in last month	0.1	0.1	0.5	0.3	-0.2	-0.4	0.0	-0.1	-0.3	-0.1	-0.1	0.3	-0.0	-0.2	0.3	-0.4	0.4	0.7	0.5	-0.1	-0.2
Hair/balding pattern: Pattern 3	0.1	0.1	0.7	-0.4	-0.1	-0.3	-0.1	0.1	0.3	-0.1	-0.2	-0.2	0.2	-0.2	-0.5	-0.1	-0.5	0.8	-0.6	-0.4	-0.2
Number of live births	0.1	0.1	0.3	-0.4	0.3	-0.5	-0.4	-0.1	0.5	0.2	-0.1	-0.3	-0.0	-0.1	-0.5	0.0	0.6	-0.3	-0.4	-0.4	-0.1
Length of working week for main job	0.1	0.1	0.6	0.1	-0.1	0.6	0.4	0.3	-0.6	-0.3	-0.2	-0.4	-0.4	-0.1	0.3	0.1	-0.5	0.8	0.0	-0.1	-0.1
Pulse wave reflection index	0.1	0.1	1.3	0.2	-0.1	0.1	0.4	0.1	-0.4	-0.1	-0.1	0.1	0.1	-0.1	-0.4	0.3	-0.4	1.1	0.2	-0.2	-0.1
Medication: Allopurinol	0.1	0.1	0.9	-0.2	-0.0	-0.1	-0.3	0.1	0.9	0.3	0.2	0.4	0.4	-0.1	-0.5	-0.1	0.8	-0.4	-0.1	0.0	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.8	-0.1	-0.1	-0.9	-0.3	0.1	-0.0	-0.4	-0.0	0.2	0.1	-0.3	-0.8	-0.3	-0.2	-0.8	-0.2	-0.1	-0.2
Alcohol intake frequency.	0.1	0.3	1.9	0.0	-0.0	-0.2	-0.1	0.1	-0.2	-0.5	-0.1	0.2	-0.1	-0.5	0.1	-0.5	-1.3	1.4	-0.1	-0.4	-0.7
Number of full sisters	0.1	0.1	0.5	-0.1	-0.0	-0.7	-0.5	0.2	-0.2	-0.1	-0.1	-0.2	-0.3	-0.1	-0.0	-0.2	-0.3	-0.1	-0.3	-0.0	-0.1
Average weekly red wine intake	0.1	0.2	0.7	0.4	0.5	0.6	0.4	0.3	-0.2	0.6	0.3	0.1	0.1	0.5	0.4	0.3	0.8	-0.8	0.3	0.5	0.5
Risk taking	0.1	0.1	0.6	-0.2	-0.4	-0.4	0.2	-0.2	0.4	0.0	-0.1	-0.1	0.1	-0.1	-0.3	-0.1	-0.4	0.8	-0.2	-0.3	-0.2
Myopia	0.1	0.2	1.3	-0.6	-0.2	-1.1	-0.3	-0.5	-0.1	-0.1	-0.2	-0.5	-0.2	-0.1	-0.6	-0.2	-0.3	0.1	-0.6	-0.3	-0.3
Blood Platelet Count	0.0	0.6	3.0	-1.1	-0.4	-0.2	-0.8	-0.9	0.1	-1.0	-0.4	-0.6	-0.4	-0.6	-1.7	-0.6	-0.4	0.0	-1.0	-0.6	-0.4
Heel T-Score	0.0	0.3	4.7	0.2	-0.4	0.1	0.1	-0.2	0.1	0.1	0.0	0.1	-0.0	0.1	-0.1	0.1	0.4	2.2	0.3	0.0	0.1
Hair Pigment	0.0	0.1	0.5	0.3	-0.0	-0.7	0.4	-0.0	-0.7	-0.3	-0.1	0.0	-0.3	-0.0	0.0	0.2	0.3	0.3	0.4	-0.2	-0.1
Birth weight of first child	0.0	0.1	0.4	-0.1	-0.3	0.7	-0.1	-0.2	-0.1	-0.1	0.1	0.2	-0.0	-0.0	-0.4	-0.1	0.1	0.6	0.0	-0.1	-0.1
Comparative height size at age 10	0.0	0.1	0.5	0.3	0.3	-0.1	0.0	0.4	-0.1	0.0	0.1	-0.4	-0.3	0.3	-0.2	0.4	-0.1	0.7	0.1	0.2	0.3

Hub : Genes

MYO19

Models

Trait associations