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chr17:39,863,901-41,675,702

Best TWAS P=1.22e-12 · Best GWAS P=2.96e-10 conditioned to 0.11

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NAGLU	0.04	0.03	bslmm	246	0.01	6.5e-02	-6.2	5.3	1.1e-07	-0.59	0.01	0.83	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PTRF	0.05	0.00	bslmm	264	0.01	6.3e-03	4.1	-5.3	1.1e-07	0.04	0.07	0.03	TRUE
3	GTEx	Adipose Subcutaneous	NAGLU	0.31	0.12	lasso	3	0.11	3.7e-09	-6.2	6.6	4.0e-11	-0.80	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	RP11-400F19.8	0.13	0.08	lasso	2	0.07	1.7e-06	-6.2	6.2	5.6e-10	-0.81	0.01	0.99	FALSE
5	GTEx	Artery Tibial	NAGLU	0.18	0.12	lasso	4	0.13	3.3e-10	-6.2	5.7	1.6e-08	-0.80	0.01	0.99	FALSE
6	GTEx	Artery Tibial	RP11-400F19.8	0.16	0.11	lasso	5	0.11	8.1e-09	-6.2	5.8	6.8e-09	-0.81	0.01	0.99	FALSE
7	GTEx	Artery Tibial	RP11-400F19.6	0.07	0.01	lasso	5	0.01	3.0e-02	-5.7	6.2	4.1e-10	-0.85	0.03	0.94	FALSE
8	GTEx	Brain Caudate basal ganglia	NAGLU	0.15	0.19	lasso	2	0.15	5.0e-05	-6.2	6.2	6.8e-10	-0.81	0.01	0.93	FALSE
9	GTEx	Cells Transformed fibroblasts	NAGLU	0.28	0.22	lasso	4	0.22	7.5e-17	-6.2	6.1	1.2e-09	-0.81	0.01	0.99	FALSE
10	GTEx	Cells Transformed fibroblasts	CNTNAP1	0.07	0.08	lasso	5	0.06	1.9e-05	-6.3	-6.4	1.8e-10	0.66	0.01	0.98	FALSE
11	GTEx	Cells Transformed fibroblasts	RP11-400F19.8	0.20	0.16	lasso	3	0.15	1.4e-11	-6.2	6.2	6.6e-10	-0.82	0.01	0.99	FALSE
12	GTEx	Cells Transformed fibroblasts	CTD-3193K9.3	0.07	0.08	lasso	3	0.07	1.2e-05	-6.3	-6.2	7.4e-10	0.62	0.01	0.99	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	TUBG2	0.15	0.10	enet	18	0.12	3.7e-05	3.2	5.3	9.8e-08	-0.70	0.29	0.39	FALSE
14	GTEx	Esophagus Mucosa	BECN1	0.24	0.08	lasso	4	0.05	5.1e-04	-6.3	-5.6	1.9e-08	0.96	0.01	0.98	FALSE
15	GTEx	Esophagus Muscularis	NAGLU	0.29	0.09	lasso	5	0.07	6.2e-05	-6.3	7.1	1.2e-12	-0.94	0.01	0.99	TRUE
16	GTEx	Esophagus Muscularis	RP11-400F19.8	0.17	0.05	lasso	4	0.02	3.9e-02	-6.3	6.8	8.8e-12	-0.82	0.01	0.86	FALSE
17	GTEx	Lung	TUBG2	0.08	0.02	enet	8	0.04	7.8e-04	2.7	5.6	2.5e-08	-0.69	0.07	0.79	FALSE
18	GTEx	Muscle Skeletal	TUBG2	0.12	0.09	lasso	8	0.10	1.1e-09	-4.9	5.9	3.5e-09	-0.88	0.03	0.97	FALSE
19	GTEx	Nerve Tibial	NAGLU	0.15	0.10	lasso	4	0.08	2.3e-06	-6.2	6.0	1.4e-09	-0.87	0.01	0.99	FALSE
20	GTEx	Nerve Tibial	RP11-400F19.8	0.10	0.03	lasso	3	0.02	8.2e-03	-6.3	6.2	4.3e-10	-1.00	0.01	0.96	FALSE
21	GTEx	Pancreas	CNTNAP1	0.13	0.09	lasso	7	0.09	9.1e-05	-6.1	-6.0	2.7e-09	0.77	0.02	0.95	FALSE
22	GTEx	Pancreas	FAM134C	0.08	0.04	enet	9	0.03	2.0e-02	-6.2	-6.2	4.2e-10	0.80	0.02	0.94	FALSE
23	GTEx	Pancreas	CTD-3193K9.3	0.12	0.07	lasso	5	0.07	5.7e-04	-6.1	-6.1	8.2e-10	0.77	0.02	0.92	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	TUBG2	0.15	0.13	lasso	5	0.12	4.0e-07	-5.7	5.6	2.2e-08	-0.88	0.16	0.84	FALSE
25	GTEx	Skin Sun Exposed Lower leg	NAGLU	0.08	0.06	enet	9	0.09	5.8e-08	-6.2	5.5	4.7e-08	-0.81	0.02	0.98	FALSE
26	GTEx	Stomach	HSD17B1P1	0.10	0.04	lasso	3	0.04	6.9e-03	-6.3	5.4	7.3e-08	-0.64	0.03	0.78	FALSE
27	METSIM	Adipose	NAGLU	0.05	0.05	lasso	4	0.05	4.5e-08	-6.2	5.4	8.2e-08	-0.79	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	NAGLU	0.19	0.03	lasso	1	0.03	9.1e-07	-6.2	6.2	5.6e-10	-0.81	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	TUBG2	0.07	0.01	enet	7	0.02	2.2e-03	-4.9	5.2	2.6e-07	-0.80	0.00	0.59	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	NAGLU	0.17	0.02	enet	11	0.07	3.4e-08	-6.2	5.4	5.7e-08	-0.63	0.00	0.99	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	NAGLU	0.59	0.09	lasso	2	0.09	6.2e-09	-6.2	6.2	5.6e-10	-0.81	0.00	1.00	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	TUBG2	0.20	0.13	blup	29	0.17	1.7e-16	-4.9	5.3	9.0e-08	-0.71	0.00	0.99	FALSE