Best TWAS P=7.25e-09 · Best GWAS P=4.46e-10 conditioned to 0.0116
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | MAP3K14-AS1 | 0.26 | 0.18 | lasso | 4 | 0.17 | 4.6e-08 | 5.7 | 5.3 | 1.0e-07 | 0.95 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | C17orf46 | 0.17 | 0.05 | blup | 36 | 0.05 | 1.9e-03 | 6.2 | 5.3 | 1.3e-07 | 0.92 | 0.00 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C17orf46 | 0.05 | 0.03 | blup | 36 | 0.03 | 4.8e-04 | -3.8 | 5.8 | 7.3e-09 | 0.84 | 0.03 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C17orf46 | 0.04 | 0.01 | lasso | 3 | 0.01 | 7.8e-02 | 5.7 | 5.7 | 1.4e-08 | 0.95 | 0.00 | 0.76 | FALSE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MGC57346 | 0.11 | 0.12 | lasso | 2 | 0.11 | 1.1e-04 | 5.7 | -5.7 | 1.5e-08 | -0.88 | 0.01 | 0.87 | FALSE |