Best TWAS P=1.15e-10 · Best GWAS P=1.43e-11 conditioned to 0.0278
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 0.00026 | 6.2 | -6.5 | 1.2e-10 | -0.90 | 0.02 | 0.95 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF652 | 0.06 | 0.03 | lasso | 4 | 0.02 | 0.00165 | 6.7 | -5.9 | 4.8e-09 | -0.76 | 0.01 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 0.00249 | 6.8 | -6.3 | 3.9e-10 | -0.87 | 0.01 | 0.96 | FALSE |