Best TWAS P=1.89e-08 · Best GWAS P=3.71e-12 conditioned to 4.31e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DCLK3 | 0.11 | 0.02 | bslmm | 427 | 0.05 | 1.9e-06 | 6.2 | -5.2 | 1.7e-07 | 0.47 | 0.04 | 0.91 | TRUE |
| 2 | GTEx | Artery Tibial | LRRFIP2 | 0.08 | 0.08 | lasso | 5 | 0.08 | 1.0e-06 | 3.8 | 5.2 | 1.9e-07 | -0.51 | 0.92 | 0.06 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | LRRFIP2 | 0.16 | -0.01 | enet | 19 | 0.01 | 2.1e-01 | 6.1 | 5.6 | 1.9e-08 | -0.31 | 0.07 | 0.26 | TRUE |