TWAS hub - LRRFIP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0380	0.0170	7.4e-04	0.004	0.016	0.015	0.017	0.003	1.0e-01	3.6e-03	4.6e-03	3.5e-03	1.2e-01
2	GTEx	Artery Aorta	0.2120	0.0610	8.9e-10	0.166	NA	0.139	NA	0.197	2.0e-09	NA	4.7e-08	NA	4.4e-11
3	GTEx	Artery Tibial	0.0842	0.0321	2.8e-05	0.076	NA	0.051	NA	0.078	1.4e-06	NA	7.2e-05	NA	1.1e-06
4	GTEx	Cells EBV-transformed lymphocytes	0.1640	0.0830	7.8e-03	-0.008	NA	0.005	NA	-0.007	8.0e-01	NA	2.1e-01	NA	6.8e-01
5	GTEx	Cells Transformed fibroblasts	0.1170	0.0400	3.7e-07	0.074	NA	0.091	NA	0.086	3.5e-06	NA	2.4e-07	NA	5.0e-07
6	GTEx	Colon Sigmoid	0.1270	0.0610	2.8e-03	0.001	NA	-0.004	NA	0.005	2.9e-01	NA	4.5e-01	NA	2.2e-01
7	GTEx	Esophagus Gastroesophageal Junction	0.1280	0.0470	3.9e-05	0.160	NA	0.069	NA	0.041	2.1e-06	NA	1.8e-03	NA	1.4e-02
8	GTEx	Esophagus Muscularis	0.1610	0.0550	3.2e-08	0.170	NA	0.126	NA	0.052	1.5e-10	NA	4.7e-08	NA	4.3e-04
9	GTEx	Muscle Skeletal	0.1078	0.0347	8.1e-10	0.103	NA	0.130	NA	0.129	2.8e-10	NA	1.1e-12	NA	1.3e-12
10	GTEx	Nerve Tibial	0.0925	0.0344	6.2e-06	0.099	NA	0.067	NA	0.075	1.8e-07	NA	1.6e-05	NA	5.8e-06
11	GTEx	Prostate	0.1490	0.0740	6.6e-03	-0.007	NA	-0.001	NA	-0.003	5.2e-01	NA	3.5e-01	NA	3.9e-01
12	GTEx	Skin Not Sun Exposed Suprapubic	0.1280	0.0450	1.3e-05	0.072	NA	0.116	NA	0.067	8.6e-05	NA	6.8e-07	NA	1.6e-04
13	GTEx	Skin Sun Exposed Lower leg	0.1100	0.0350	1.3e-06	0.046	NA	0.056	NA	0.079	1.0e-04	NA	1.9e-05	NA	4.0e-07
14	GTEx	Testis	0.1170	0.0440	3.7e-05	0.047	NA	0.109	NA	0.083	3.9e-03	NA	1.6e-05	NA	1.6e-04
15	GTEx	Thyroid	0.3830	0.0480	0.0e+00	0.552	NA	0.595	NA	0.591	4.2e-50	NA	3.8e-56	NA	1.6e-55
16	GTEx	Whole Blood	0.0420	0.0190	1.7e-03	0.052	NA	0.029	NA	0.039	1.4e-05	NA	9.8e-04	NA	1.4e-04
17	NTR	Blood	0.0253	0.0084	1.7e-09	0.035	0.031	0.028	0.032	0.036	1.9e-11	1.9e-10	2.3e-09	1.1e-10	8.6e-12
18	ROSMAP	Brain Pre-frontal Cortex	0.0918	0.0286	1.1e-09	0.090	0.076	0.079	0.079	0.083	1.2e-11	5.7e-10	2.1e-10	2.4e-10	7.4e-11
19	TCGA	Breast Invasive Carcinoma	0.0240	0.0160	6.3e-07	0.026	0.026	0.019	NA	0.024	3.1e-06	3.0e-06	5.8e-05	NA	7.8e-06
20	TCGA	Head and Neck Squamous Cell Carcinoma	0.0248	0.0179	8.0e-04	0.013	0.016	0.004	NA	0.003	1.1e-02	5.7e-03	9.1e-02	NA	1.4e-01
21	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1670	0.0940	1.1e-04	0.101	0.077	0.061	NA	0.083	2.2e-06	3.6e-05	2.1e-04	NA	1.8e-05
22	TCGA	Brain Lower Grade Glioma	0.0329	0.0434	7.6e-03	0.010	-0.002	0.011	NA	0.009	2.5e-02	8.8e-01	1.8e-02	NA	2.7e-02
23	TCGA	Pancreatic Adenocarcinoma	0.0880	0.0600	1.9e-04	0.115	0.076	0.088	NA	0.049	1.6e-05	4.2e-04	1.5e-04	NA	4.1e-03
24	TCGA	Thyroid Carcinoma	0.2360	0.0760	0.0e+00	0.376	0.367	0.376	NA	0.370	1.6e-38	2.4e-37	2.1e-38	NA	9.5e-38

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Hypothyroidism/myxoedema (self-reported)	13.7	26.7	34.4	-5.9	-4.8	-5.6	-3.8	-5.1	-5.5	-4.7	-5.4	-5.7	-5.6	-4.7	4.1	4.5	-5.2	-5.5	5.6	5.5	-5.5	-5.6	-5.3	-4.2	-5.2	-5.0	-5.4
Hypothyroidism (self reported)	11.4	26.1	32.9	-5.6	-4.5	-5.5	-3.2	-5.3	-5.7	-4.5	-5.4	-5.7	-5.6	-4.5	4.3	4.3	-5.1	-5.6	5.6	5.4	-5.5	-5.6	-5.3	-4.0	-5.2	-4.8	-5.4
Medication: Levothyroxine sodium	11.1	18.9	25.4	-5.0	-4.0	-4.5	-2.2	-4.4	-4.1	-4.2	-4.7	-4.8	-4.6	-3.6	4.1	3.6	-4.5	-4.6	4.7	4.7	-4.7	-4.8	-4.5	-3.7	-4.3	-4.3	-4.6
Bipolar Disorder (2018)	10.0	15.8	31.6	4.0	2.9	5.2	5.6	4.2	4.5	3.5	3.8	4.9	3.4	4.4	-4.5	-3.7	4.1	3.7	-3.7	-3.4	3.8	3.8	3.6	3.4	3.6	3.0	3.4
Bipolar Disorder or Schizophrenia	8.5	20.7	55.2	4.1	3.7	6.1	7.4	4.3	5.6	3.9	4.2	5.3	3.8	5.9	-4.5	-5.1	4.4	3.9	-4.1	-4.0	4.1	4.0	4.1	2.7	4.2	3.4	3.8
Medication: Gliclazide	8.3	9.3	15.9	-4.0	-2.9	-3.6	-2.8	-3.4	-2.9	-2.3	-2.9	-3.1	-3.4	-3.2	2.2	1.9	-3.8	-3.1	3.1	3.0	-2.6	-3.4	-2.6	-3.7	-2.6	-3.0	-2.9
Diabetes (mother)	7.4	9.4	12.3	-2.8	-3.3	-3.1	-2.2	-2.7	-3.2	-2.5	-3.2	-2.8	-3.4	-2.7	3.0	2.6	-3.0	-3.2	3.5	3.5	-3.2	-3.4	-3.5	-2.1	-3.3	-3.5	-3.4
Had other major operations	6.6	8.1	12.2	-3.1	-2.9	-2.9	-1.7	-2.8	-3.0	-3.4	-3.1	-2.9	-3.5	-2.4	1.9	2.6	-2.4	-2.9	2.8	3.0	-3.2	-3.0	-3.0	-2.2	-3.3	-2.9	-2.8
Heart disease (mother)	6.2	7.6	14.6	-1.1	-2.9	-2.9	-1.8	-3.6	-2.0	-2.3	-2.5	-2.6	-2.2	-3.6	2.5	3.8	-3.4	-2.3	2.4	2.8	-2.6	-2.6	-2.6	-3.3	-2.9	-3.0	-2.5
Eye problems/disorders: Glaucoma	4.6	5.5	8.6	-1.4	-2.5	-2.3	-1.7	-2.5	-1.8	-2.5	-2.2	-2.8	-2.5	-2.9	1.9	2.0	-2.8	-2.4	2.8	2.5	-2.1	-2.7	-2.5	-1.3	-2.2	-2.1	-2.6
Trunk fat percentage	4.4	17.4	29.4	-5.4	-3.8	-3.9	-1.5	-3.8	-3.3	-4.9	-4.3	-4.4	-5.2	-3.9	2.6	3.7	-3.2	-4.9	5.4	4.8	-3.8	-4.7	-5.0	-1.2	-4.6	-3.5	-4.8
High blood pressure (siblings)	4.3	6.2	16.2	-1.6	-3.1	-2.6	-1.5	-2.6	-2.3	-2.9	-2.4	-2.6	-2.5	-4.0	2.3	2.2	-1.8	-2.2	2.4	2.6	-2.7	-2.5	-2.6	-2.0	-2.4	-2.7	-2.2
Trunk fat mass	4.1	17.7	29.6	-5.4	-3.8	-4.0	-1.9	-3.8	-3.4	-4.8	-4.4	-4.5	-5.2	-4.0	2.6	3.8	-3.2	-5.0	5.4	4.8	-3.9	-4.8	-5.0	-1.1	-4.7	-3.5	-4.9
Other serious medical condition/disability diagnosed by doctor	4.0	5.2	7.6	-2.6	-2.3	-2.5	-0.6	-1.8	-1.4	-2.6	-2.4	-2.1	-2.4	-2.7	1.7	2.4	-2.5	-2.1	2.4	2.5	-2.8	-2.4	-2.5	-0.9	-2.3	-2.7	-2.3
Schizophrenia (2014)	3.9	8.6	19.7	2.3	2.5	4.1	4.4	2.5	3.3	2.7	2.6	3.6	2.7	4.2	-2.6	-3.7	2.5	2.5	-2.9	-2.6	2.5	2.6	2.8	1.3	2.8	2.0	2.6
Prospective memory result	3.9	4.8	8.4	-2.0	-2.3	-2.4	-1.9	-2.3	-2.4	-2.0	-2.2	-1.9	-1.8	-2.9	2.5	1.8	-2.8	-2.1	2.3	2.2	-2.1	-2.2	-2.1	-1.7	-2.0	-2.2	-2.2
Qualifications: CSEs or equivalent	3.8	5.0	8.0	1.0	2.8	2.1	0.9	1.7	1.8	2.2	2.3	2.2	2.3	2.1	-2.3	-2.3	1.3	2.7	-2.6	-2.8	2.3	2.5	2.7	0.5	2.7	2.4	2.8
Schizophrenia (2018)	3.5	7.2	24.6	2.1	2.4	3.7	5.0	2.1	3.5	2.2	2.4	2.9	2.2	4.1	-2.2	-3.5	2.4	2.0	-2.4	-2.3	2.2	2.1	2.4	0.7	2.4	1.9	2.1
Falls in the last year	3.4	4.6	7.7	-1.7	-1.9	-2.8	-1.6	-2.8	-2.1	-2.1	-1.9	-2.7	-2.3	-2.6	0.8	2.5	-1.7	-2.2	2.1	2.0	-1.8	-2.2	-2.1	-2.2	-2.3	-2.3	-2.1
Wears glasses or contact lenses	3.3	3.8	5.7	-1.8	-1.8	-1.8	-0.3	-2.2	-1.6	-2.2	-1.8	-2.4	-2.1	-1.9	1.8	2.1	-1.8	-2.3	2.2	2.0	-2.0	-2.1	-2.2	-0.9	-2.2	-1.4	-2.2
Body fat percentage	3.2	12.6	25.7	-5.1	-3.1	-3.3	-1.7	-3.0	-2.8	-4.2	-3.6	-3.7	-4.5	-3.2	1.9	3.4	-2.5	-4.2	4.7	4.1	-3.2	-4.0	-4.3	-0.4	-4.0	-2.8	-4.1
Number of operations (self-reported)	3.2	4.8	7.2	-2.4	-2.0	-2.7	-1.8	-2.1	-2.0	-2.6	-2.4	-2.2	-2.3	-2.1	1.5	2.1	-1.8	-2.4	2.1	2.1	-2.7	-2.3	-2.2	-1.4	-2.4	-2.3	-2.2
Risk taking	3.2	4.6	7.9	1.4	1.9	2.4	1.9	2.6	1.9	2.2	1.8	2.2	1.8	2.4	-1.7	-2.7	2.8	2.2	-2.4	-2.2	1.8	2.2	2.0	2.2	2.4	1.5	2.3
Glaucoma (self-reported)	3.0	3.6	7.1	-1.1	-2.2	-1.9	-1.1	-2.1	-1.0	-2.0	-1.8	-2.1	-2.0	-2.6	1.5	1.5	-2.7	-1.8	2.1	2.0	-1.8	-2.1	-2.0	-1.2	-1.8	-2.0	-2.0
Basal cell carcinoma (self-reported)	3.0	3.6	8.6	-1.6	-2.0	-1.4	-0.4	-2.1	-1.3	-1.7	-1.9	-2.2	-2.0	-1.8	1.2	1.8	-2.9	-1.9	1.9	2.1	-1.9	-2.1	-2.0	-1.6	-2.1	-1.9	-2.1
Ulcerative Colitis (UC)	2.9	5.5	8.6	2.4	2.6	2.8	1.5	2.3	2.5	2.7	2.3	1.7	2.9	2.0	-0.9	-2.2	1.7	2.2	-2.9	-2.9	2.4	2.6	2.7	1.1	2.6	2.5	2.4
Number of children fathered	2.9	3.3	5.1	-1.4	-1.8	-1.9	-1.8	-1.7	-2.1	-1.7	-1.8	-1.8	-1.6	-2.1	1.6	2.3	-1.9	-1.6	1.8	2.0	-2.0	-1.8	-1.8	-1.4	-1.9	-1.7	-1.8
Whole body fat mass	2.9	12.1	23.0	-4.8	-3.0	-3.3	-2.1	-3.0	-3.0	-4.0	-3.6	-3.8	-4.4	-3.4	2.1	3.2	-2.3	-4.1	4.5	3.9	-3.1	-3.9	-4.2	-0.5	-3.9	-2.6	-4.0
Respiratory disease	2.8	6.1	11.6	2.0	2.4	2.8	2.1	2.9	2.4	2.0	2.1	2.3	2.4	2.3	-2.0	-2.1	3.4	2.5	-2.6	-2.5	2.5	2.7	2.2	3.3	2.5	2.4	2.4
Alzheimer’s Disease (including proxy)	2.7	4.0	6.7	0.7	1.8	2.1	1.1	2.3	2.3	1.9	2.2	2.1	1.9	2.4	-2.6	-2.4	1.3	2.2	-2.0	-1.9	2.0	2.0	1.9	2.0	2.2	1.5	2.0
Systolic blood pressure, automated reading	2.7	7.8	22.0	-1.4	-3.3	-3.0	-2.4	-2.1	-2.8	-2.8	-2.7	-3.4	-2.6	-4.7	3.0	3.8	-1.3	-2.5	2.8	2.8	-2.6	-2.5	-2.9	-1.2	-3.1	-2.4	-2.6
Stomach or abdominal pain in last month	2.7	3.4	8.0	1.9	1.7	1.7	1.1	1.8	2.6	2.1	2.0	1.6	1.5	1.4	-2.0	-2.8	2.5	1.6	-1.6	-1.8	1.4	1.5	1.6	1.6	2.1	1.4	1.7
Leg pain on walking	2.7	3.4	6.3	-2.5	-1.7	-2.5	-0.8	-2.4	-1.4	-2.0	-1.8	-1.9	-1.7	-1.8	1.9	1.2	-1.9	-1.6	1.6	1.9	-2.1	-1.9	-1.7	-1.7	-1.3	-2.5	-1.6
Coronary Artery Disease (CAD)	2.5	3.0	7.2	-0.5	-1.8	-1.3	-2.5	-1.8	-2.7	-1.5	-1.5	-2.3	-1.1	-2.3	2.4	1.9	-1.4	-1.8	1.5	1.9	-1.3	-1.3	-1.6	-0.7	-1.7	-1.3	-1.6
Commuting to job workplace: Walk	2.5	2.7	4.0	-1.8	-1.4	-1.9	0.6	-1.4	-1.7	-1.7	-1.9	-1.7	-2.0	-1.6	1.8	1.9	-0.8	-1.8	1.7	1.7	-1.8	-1.7	-1.9	-0.9	-1.9	-1.3	-1.7
Asthma (self-reported)	2.5	5.0	12.7	1.5	2.0	2.6	2.0	3.1	1.5	1.5	1.8	2.2	1.7	2.1	-2.2	-1.6	3.5	2.1	-2.1	-2.0	2.2	2.4	1.8	3.6	1.9	2.4	2.1
Lung FVC	2.4	12.0	18.6	2.5	4.3	3.5	1.0	2.9	3.2	3.8	3.9	3.5	3.5	4.1	-3.8	-3.7	3.2	3.4	-3.7	-3.9	3.4	3.5	3.7	1.7	3.7	3.5	3.7
Average weekly spirits intake	2.4	2.9	6.5	-0.0	2.2	2.1	0.3	2.3	1.5	1.6	1.6	1.9	1.6	2.5	-2.3	-1.0	1.7	1.4	-1.5	-1.8	1.8	1.7	1.6	1.6	1.2	2.1	1.5
Asthma	2.4	4.8	13.4	1.1	2.0	2.6	1.9	3.2	1.4	1.4	1.7	2.3	1.6	2.0	-2.4	-1.5	3.3	2.1	-1.9	-2.0	2.1	2.4	1.7	3.7	1.8	2.5	2.1
Arm fat mass (right)	2.4	10.1	21.6	-4.7	-2.6	-3.0	-1.8	-2.7	-2.8	-3.6	-3.2	-3.5	-4.0	-2.9	1.8	3.0	-2.4	-3.8	4.1	3.5	-2.7	-3.5	-3.7	-0.6	-3.5	-2.3	-3.6
Knee pain experienced in last month	2.4	3.7	8.2	-1.7	-1.9	-2.3	-0.5	-2.6	-1.6	-2.1	-1.8	-2.0	-1.2	-2.1	2.4	2.4	-2.0	-1.5	1.4	1.9	-1.5	-1.6	-1.4	-2.9	-1.8	-2.3	-1.5
Height	2.3	44.8	59.4	-5.2	-7.1	-6.8	-1.6	-7.2	-6.1	-7.0	-7.4	-7.2	-7.4	-7.7	7.5	4.4	-5.5	-7.1	7.0	7.4	-7.3	-7.5	-7.4	-4.8	-6.3	-7.3	-7.2
Illnesses of siblings: Diabetes	2.3	2.8	4.5	-1.7	-1.7	-1.4	-0.5	-1.7	-1.7	-2.0	-1.8	-1.4	-2.0	-1.5	1.4	2.1	-1.6	-1.8	2.0	1.9	-1.9	-1.7	-2.0	-0.6	-2.1	-1.3	-1.7
Breast Cancer	2.2	5.3	13.6	2.1	2.2	1.8	2.5	1.7	3.2	2.7	2.6	2.4	2.3	2.7	-3.7	-2.2	1.2	2.1	-2.1	-2.2	1.9	2.1	2.4	0.9	2.2	2.0	2.2
Bipolar Disorder (2011)	2.2	2.1	12.9	1.7	0.6	2.1	3.6	1.1	1.9	0.9	1.2	2.1	1.0	1.7	-1.9	-1.4	1.4	0.9	-1.0	-0.7	1.1	1.0	0.7	1.2	0.8	0.4	0.7
Illnesses of siblings	2.2	3.0	10.3	1.1	2.1	1.7	0.8	1.6	1.8	2.0	1.6	1.7	1.7	3.2	-1.3	-1.8	0.9	1.7	-1.9	-1.8	2.0	1.7	1.9	0.8	1.6	1.7	1.7
Arm fat percentage (right)	2.2	8.8	20.8	-4.6	-2.5	-2.6	-1.2	-2.5	-2.4	-3.5	-2.9	-3.1	-3.7	-2.2	1.4	2.9	-2.3	-3.6	4.0	3.4	-2.4	-3.3	-3.5	-0.3	-3.4	-2.1	-3.5
Arm fat percentage (left)	2.1	8.4	21.6	-4.6	-2.3	-2.6	-1.4	-2.3	-2.4	-3.5	-2.9	-3.1	-3.8	-2.2	1.2	2.5	-2.2	-3.5	3.9	3.3	-2.3	-3.3	-3.5	-0.2	-3.2	-2.0	-3.3
Arm fat mass (left)	2.1	8.5	18.8	-4.3	-2.3	-2.7	-1.8	-2.3	-2.6	-3.4	-3.0	-3.2	-3.8	-2.7	1.5	2.6	-2.0	-3.5	3.8	3.2	-2.4	-3.2	-3.5	-0.2	-3.2	-2.0	-3.3
Schizophrenia vs Biploar Disorder	2.0	2.7	6.6	-1.9	-1.2	-2.0	-0.9	-2.1	-1.6	-1.3	-1.6	-1.4	-1.5	-1.4	2.0	1.1	-1.5	-1.6	1.5	1.6	-1.8	-1.9	-1.3	-2.6	-1.4	-1.7	-1.4
Weight	2.0	9.7	18.8	-4.3	-2.6	-3.0	-2.1	-2.7	-2.7	-3.5	-3.2	-3.6	-3.9	-3.4	1.9	2.7	-1.9	-3.7	4.0	3.3	-2.8	-3.4	-3.7	-0.4	-3.3	-2.4	-3.5
Standing height	2.0	19.6	26.3	-3.8	-4.3	-4.2	-1.6	-4.8	-4.4	-4.7	-4.9	-4.7	-4.9	-4.8	4.3	2.9	-3.9	-5.1	4.8	4.9	-4.7	-5.0	-4.9	-3.1	-4.2	-4.7	-5.0
Neck or shoulder pain in last month	2.0	2.8	5.5	2.3	2.0	1.2	0.5	1.8	0.8	1.9	1.8	1.3	1.7	1.0	-1.6	-1.3	2.4	1.7	-1.8	-2.0	1.5	1.7	1.9	0.6	2.0	1.9	1.8
Alzheimer’s Disease (in father)	1.9	2.1	6.1	1.8	0.8	1.4	0.8	1.5	2.5	1.5	1.6	1.6	1.6	1.2	-0.9	-1.2	1.5	1.4	-1.6	-1.3	1.4	1.6	1.2	1.7	1.1	0.9	1.4
Long-standing illness, disability or infirmity	1.9	3.0	5.2	-1.6	-1.8	-1.9	-0.6	-1.6	-1.9	-1.9	-1.9	-1.7	-1.6	-2.2	2.1	2.3	-1.4	-1.5	1.5	1.9	-1.6	-1.5	-1.7	-0.7	-1.8	-2.0	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.9	3.0	6.2	1.5	2.0	1.7	1.6	1.4	0.8	1.6	1.7	1.9	1.8	2.5	-1.7	-1.6	1.4	1.9	-2.2	-1.9	1.6	1.8	2.0	0.5	1.8	1.5	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	5.4	-1.5	-1.6	-2.3	-0.9	-1.8	-1.2	-1.4	-1.4	-1.9	-1.5	-1.7	0.6	1.2	-1.4	-1.6	1.7	1.8	-1.8	-1.8	-1.5	-1.5	-1.2	-2.0	-1.5
Illnesses of mother	1.8	2.2	4.0	0.7	1.6	1.4	-0.2	1.8	1.0	1.1	1.5	1.6	1.2	2.0	-1.8	-1.5	1.7	1.6	-1.4	-1.5	1.5	1.6	1.5	1.6	1.4	1.7	1.7
Health satisfaction	1.8	2.3	4.0	-1.4	-1.7	-1.7	-0.1	-1.3	-1.1	-1.6	-1.9	-2.0	-1.6	-1.8	1.8	1.4	-0.9	-1.5	1.3	1.5	-1.8	-1.5	-1.6	-0.6	-1.5	-1.8	-1.4
Eye problems/disorders: None of the above	1.8	2.1	6.0	0.8	1.4	1.7	1.1	1.7	1.4	1.1	1.2	1.8	1.4	1.4	-0.9	-1.3	2.4	1.4	-1.5	-1.4	0.9	1.5	1.3	1.5	1.4	1.4	1.4
Unable to work because of sickness or disability	1.8	2.4	5.4	-2.0	-1.5	-1.8	-1.0	-1.6	-0.8	-1.6	-1.6	-1.5	-1.5	-1.7	1.5	0.7	-1.6	-1.3	1.2	1.5	-1.9	-1.6	-1.5	-1.7	-1.0	-2.3	-1.4
Leg fat mass (left)	1.8	6.8	15.7	-4.0	-1.9	-2.4	-2.1	-2.0	-2.0	-3.1	-2.6	-2.9	-3.3	-2.6	1.1	2.6	-1.2	-3.1	3.5	2.8	-2.3	-2.8	-3.3	0.5	-3.0	-1.7	-3.0
Mean Putamen Volume	1.7	1.9	4.2	-1.9	-1.2	-1.0	0.3	-2.0	-1.3	-1.9	-1.4	-1.3	-1.7	-1.2	1.2	0.9	-0.5	-1.6	1.5	1.3	-1.3	-1.6	-1.4	-1.4	-1.4	-1.4	-1.4
Type 2 Diabetes (T2D) (2018)	1.7	3.2	7.0	-1.8	-1.5	-2.2	-2.3	-1.5	-1.7	-1.2	-1.7	-2.0	-1.9	-1.7	1.4	1.9	-2.6	-1.8	2.0	1.8	-1.5	-1.8	-1.9	-1.1	-1.9	-1.3	-1.8
Lung FEV1/FVC ratio	1.7	8.7	14.9	-2.4	-3.1	-2.5	-1.6	-3.0	-3.2	-3.3	-2.6	-3.6	-2.9	-2.7	2.9	3.0	-2.6	-3.9	3.5	3.3	-2.1	-3.1	-3.1	-1.6	-3.5	-2.3	-3.7
Hip circumference	1.7	7.2	11.6	-3.3	-2.5	-2.5	-1.1	-2.6	-2.3	-3.2	-2.6	-3.4	-3.4	-3.2	1.7	2.2	-1.7	-3.2	3.4	2.8	-2.3	-2.9	-3.2	-0.3	-2.9	-2.0	-3.0
Ever highly irritable/argumentative for 2 days	1.7	2.1	3.7	-1.9	-1.1	-1.8	-0.4	-1.7	-1.2	-1.7	-1.6	-1.6	-1.7	-1.5	1.6	0.8	-0.7	-1.4	1.4	1.4	-1.8	-1.6	-1.5	-1.3	-1.0	-1.5	-1.2
Ever had prostate specific antigen (PSA) test	1.7	2.0	3.7	-0.3	-1.6	-1.2	0.2	-1.7	-0.5	-1.8	-1.2	-1.5	-1.4	-1.9	1.7	1.5	-1.1	-1.9	1.3	1.4	-1.6	-1.4	-1.7	-0.3	-1.6	-1.3	-1.7
Crohns Disease (2012)	1.6	2.5	4.5	-1.8	-1.9	-1.4	-1.1	-1.4	-1.3	-2.1	-1.6	-1.6	-1.9	-1.3	0.9	1.2	-1.2	-1.8	1.9	1.8	-1.6	-1.7	-1.9	-0.2	-1.6	-1.7	-1.9
Waist circumference	1.6	5.9	13.4	-3.7	-1.9	-2.4	-1.8	-1.7	-1.7	-2.7	-2.5	-2.9	-3.3	-2.3	0.6	2.6	-1.5	-2.9	3.2	2.6	-2.2	-2.7	-2.9	-0.2	-2.9	-1.6	-2.7
Time employed in main current job	1.6	1.8	4.9	1.3	1.0	1.4	1.0	2.2	1.1	1.9	1.0	1.1	1.4	0.8	0.3	-0.5	2.0	1.1	-1.3	-1.3	1.2	1.5	1.3	2.0	1.0	1.7	1.2
Pulse wave reflection index	1.6	2.0	5.2	-0.9	-1.4	-1.4	-0.6	-0.2	-2.3	-1.9	-1.4	-1.2	-1.8	-1.9	1.1	1.4	-0.4	-1.4	1.6	1.5	-1.5	-1.4	-1.7	0.4	-1.6	-1.0	-1.4
Comparative body size at age 10	1.6	4.3	5.8	1.7	1.8	2.4	1.1	2.2	2.2	2.4	2.0	2.2	2.2	2.4	-1.6	-2.3	2.1	1.9	-2.1	-2.0	2.1	2.1	2.2	2.0	2.1	2.1	2.0
Age at first live birth	1.6	2.8	4.7	2.0	1.6	2.1	0.3	2.2	1.6	1.3	1.6	1.9	1.7	1.9	-1.6	-1.7	1.6	1.7	-1.8	-1.8	1.3	1.6	1.8	1.2	1.7	1.7	1.6
Leg fat mass (right)	1.6	6.1	13.7	-3.7	-1.8	-2.2	-2.1	-1.8	-1.9	-3.0	-2.4	-2.8	-3.2	-2.3	1.2	2.5	-1.2	-3.0	3.4	2.7	-2.1	-2.6	-3.1	0.6	-2.8	-1.4	-2.8
Alcohol drinker status: Never	1.6	2.0	4.5	0.8	-1.7	-0.7	-0.1	-1.8	-1.6	-1.6	-1.0	-1.2	-1.3	-1.3	1.7	2.1	-1.3	-1.6	1.2	1.7	-0.5	-1.0	-1.6	-0.2	-1.9	-1.5	-1.7
Alzheimer’s Disease (in mother)	1.5	1.7	5.2	-0.3	1.4	1.6	0.9	1.8	0.8	1.1	1.0	1.3	0.7	2.2	-1.7	-2.3	0.3	1.4	-1.1	-1.2	1.0	1.0	1.2	1.1	1.6	0.9	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	4.0	1.0	1.0	0.7	-0.4	1.8	1.6	1.9	1.3	1.4	1.5	0.8	-1.6	-0.6	0.0	2.0	-1.1	-1.4	0.9	1.6	1.3	1.3	1.3	1.1	1.7
Noisy workplace	1.4	1.8	3.3	0.1	1.7	1.0	1.2	1.1	0.5	1.4	1.2	1.4	1.4	1.8	-1.2	-0.6	1.4	1.4	-1.4	-1.3	1.3	1.5	1.2	1.8	1.3	1.7	1.5
Length of working week for main job	1.4	1.6	3.3	-1.5	-1.2	-1.3	-1.0	-1.4	-0.6	-1.7	-1.5	-1.2	-1.3	-0.9	0.7	1.1	-1.4	-0.8	1.2	1.3	-1.7	-1.3	-1.1	-1.8	-1.1	-1.4	-1.0
Angina (self-reported)	1.4	1.8	6.9	1.4	1.6	0.8	0.9	0.6	1.6	1.4	1.2	1.2	1.8	1.1	-0.8	-1.1	2.6	1.1	-1.6	-1.5	0.9	1.4	1.3	1.5	1.3	1.0	1.4
Osteoporosis (self-reported)	1.4	1.7	3.9	-1.3	-1.1	-1.2	-1.3	-0.8	-1.4	-1.1	-1.5	-1.4	-1.8	-1.4	0.4	0.9	-0.5	-1.6	2.0	1.3	-1.4	-1.7	-1.6	-0.8	-1.5	-0.9	-1.6
Medication: Atorvastatin	1.4	1.7	3.5	-0.6	-1.5	-1.6	-1.1	-1.1	-0.6	-0.8	-1.3	-1.0	-1.0	-1.8	1.5	1.7	-1.2	-1.1	1.0	1.4	-1.6	-1.3	-1.5	-0.9	-1.6	-1.9	-1.3
Verbal and Numeric Reasoning (VNR)	1.3	3.2	9.3	-1.2	-1.7	-1.4	-0.1	-1.3	-2.4	-2.0	-1.6	-1.1	-1.8	-1.1	1.0	3.0	-2.1	-1.6	2.3	2.1	-1.8	-1.7	-2.1	-0.7	-2.4	-1.5	-2.0
Age at First Birth	1.3	1.9	4.4	2.1	1.3	1.4	1.1	0.9	2.1	1.8	1.5	1.7	1.3	1.6	-1.5	-0.3	0.9	1.4	-1.0	-1.3	1.6	1.3	1.1	0.9	0.7	1.5	1.3
HDL Cholesterol	1.3	2.2	4.2	1.3	1.2	1.4	-0.0	2.0	1.3	1.3	1.6	1.6	1.6	1.1	-0.6	-1.5	1.8	1.8	-1.8	-1.5	0.9	1.7	1.6	2.0	1.6	1.3	1.7
Ulcerative Colitis	1.3	1.9	3.9	0.9	1.9	2.0	1.5	1.2	1.6	1.3	1.3	0.7	1.5	1.3	-0.6	-1.3	0.7	1.0	-1.6	-1.9	1.5	1.5	1.5	1.0	1.4	1.8	1.2
Angina	1.3	1.7	7.3	1.5	1.5	0.8	0.9	0.7	1.5	1.2	1.2	1.3	1.7	1.1	-0.7	-1.0	2.7	1.0	-1.5	-1.4	0.9	1.3	1.2	1.6	1.2	1.0	1.3
Supplements: Zinc	1.3	1.4	5.1	0.6	1.2	0.9	-0.1	1.4	0.8	1.0	1.3	1.1	0.8	1.2	-1.5	-2.3	1.1	1.1	-1.0	-1.2	1.0	1.0	1.2	1.5	1.8	1.1	1.1
Severe depression (siblings)	1.3	1.5	4.3	0.4	1.0	1.8	0.2	1.4	1.7	0.8	1.3	1.3	0.8	2.1	-1.7	-1.8	0.5	1.1	-0.8	-0.9	1.2	1.0	0.9	1.3	1.1	1.0	1.0
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.7	-0.1	1.8	0.8	-0.8	1.2	0.6	1.5	1.3	1.1	1.6	1.4	-1.3	-0.2	1.2	1.2	-1.4	-1.5	1.1	1.6	1.3	1.9	0.9	1.7	1.4
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.2	1.8	1.2	1.2	1.0	0.5	1.5	1.6	1.4	1.1	1.4	0.7	-0.2	-1.2	0.1	1.4	-1.4	-1.3	1.1	1.1	1.3	-0.5	1.4	0.8	1.4
Impedance of arm (right)	1.2	5.4	9.5	-1.9	-2.5	-1.7	1.1	-2.4	-2.2	-2.9	-2.5	-1.6	-2.6	-0.8	2.2	0.8	-2.3	-2.7	2.6	3.1	-2.3	-2.8	-2.5	-2.2	-2.2	-2.9	-2.9
Mouth/teeth dental problems: Dentures	1.2	2.1	4.0	-0.7	-1.4	-1.4	0.2	-1.5	-1.9	-1.5	-1.5	-1.7	-1.3	-1.9	1.9	2.0	-1.4	-1.2	1.3	1.5	-1.0	-1.3	-1.7	-0.4	-1.7	-1.1	-1.4
Shortness of breath walking on level ground	1.2	1.4	2.7	-1.6	-0.7	-0.8	-1.3	0.4	-1.4	-1.6	-1.3	-0.9	-1.4	-1.6	1.3	0.4	0.5	-1.0	1.5	1.3	-1.4	-1.2	-1.4	1.2	-0.6	-0.7	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.2	-1.3	-0.7	-1.4	-1.5	-1.8	-1.6	-1.1	-1.1	-1.2	-1.1	-1.3	0.8	1.8	-0.5	-1.3	0.8	0.9	-1.2	-1.0	-0.9	-1.5	-1.4	-0.8	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	4.8	0.8	2.2	1.4	-0.7	1.5	1.4	1.9	1.8	1.2	1.3	1.9	-1.9	-2.1	1.1	1.6	-1.6	-2.0	1.6	1.6	1.6	1.1	1.9	1.4	1.7
Leg fat percentage (left)	1.2	4.4	13.0	-3.6	-1.5	-2.0	-1.9	-1.2	-1.3	-2.6	-2.0	-2.2	-2.7	-1.9	0.5	2.4	-0.7	-2.3	2.8	2.2	-1.9	-2.2	-2.7	0.9	-2.5	-1.2	-2.2
Crohns Disease (2017)	1.1	2.3	3.6	-1.8	-1.5	-1.3	-1.4	-1.6	-1.3	-1.9	-1.7	-1.9	-1.6	-0.9	0.8	0.8	-1.7	-1.9	1.5	1.6	-1.6	-1.6	-1.7	-0.4	-1.5	-1.7	-1.9
Systolic Blood Pressure	1.1	5.5	21.1	0.2	-3.1	-2.2	-2.1	-1.6	-2.6	-2.6	-2.1	-2.4	-2.0	-4.6	2.9	3.6	-0.7	-1.9	2.2	2.3	-1.8	-1.9	-2.3	-0.6	-2.6	-1.9	-2.1
Leg predicted mass (left)	1.1	5.9	10.5	-3.0	-2.0	-2.1	-1.0	-2.4	-2.2	-2.6	-2.5	-2.9	-3.2	-2.7	1.6	1.9	-1.6	-3.1	3.2	2.5	-2.0	-2.8	-2.9	-0.5	-2.5	-1.8	-2.9
Fluid intelligence score	1.1	2.2	6.4	-1.1	-1.4	-1.1	-0.8	-0.8	-2.4	-1.5	-1.2	-1.2	-1.6	-0.8	0.2	2.5	-2.0	-1.5	1.9	1.7	-1.3	-1.4	-1.6	-0.8	-2.0	-1.1	-1.7
Migraine (self-reported)	1.1	1.3	2.3	0.5	1.4	1.1	1.5	1.0	0.7	0.7	1.2	0.9	1.4	1.4	-1.1	-0.4	1.1	1.1	-1.1	-1.3	1.4	1.4	1.1	1.3	1.0	1.1	1.2
Comparative height size at age 10	1.1	5.9	10.1	-2.4	-2.1	-2.3	-1.0	-2.5	-1.8	-2.4	-2.9	-2.9	-2.8	-2.6	1.8	1.6	-1.4	-3.2	2.6	2.5	-2.8	-3.0	-2.6	-2.2	-2.4	-2.1	-2.9
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.6	1.0	1.3	0.7	1.0	1.1	0.4	1.2	0.9	0.8	0.9	1.1	-0.1	-1.7	1.9	0.9	-1.0	-1.1	0.9	0.9	0.9	1.0	1.4	0.7	1.1
Leg predicted mass (right)	1.1	6.0	10.1	-3.1	-1.9	-2.2	-0.9	-2.5	-2.3	-2.6	-2.6	-2.8	-3.2	-2.8	1.6	1.8	-1.7	-3.1	3.2	2.5	-2.2	-2.8	-2.8	-0.8	-2.5	-1.9	-2.8
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.8	1.2	1.2	0.9	-0.1	1.4	0.3	1.0	1.1	0.7	1.0	0.7	-1.6	-0.7	0.6	1.0	-1.4	-1.4	0.9	1.4	1.1	2.0	1.0	1.6	1.2
Ever depressed for a whole week	1.1	1.3	4.2	0.8	1.5	1.5	2.0	0.5	0.4	0.7	1.2	0.5	0.5	1.4	-1.5	-1.5	1.2	0.7	-1.2	-1.2	1.0	1.1	1.0	1.0	1.0	1.3	1.2
Ovarian Cancer	1.0	1.3	6.7	0.8	0.9	1.3	2.6	1.1	0.7	0.8	1.2	1.2	1.4	1.3	-0.9	0.4	0.1	1.3	-1.1	-0.9	1.2	1.2	0.9	0.7	0.5	1.2	1.1
Leg fat-free mass (left)	1.0	5.6	10.1	-2.9	-1.9	-2.1	-0.9	-2.3	-2.2	-2.5	-2.4	-2.8	-3.1	-2.7	1.6	1.8	-1.6	-3.0	3.2	2.5	-1.9	-2.7	-2.8	-0.5	-2.4	-1.7	-2.8
High blood pressure (mother)	1.0	1.4	3.8	0.2	-1.4	-1.1	0.2	-1.5	-0.3	-0.7	-1.1	-1.1	-1.0	-1.5	1.9	0.8	-1.0	-1.6	0.9	1.3	-1.2	-1.4	-1.1	-1.5	-1.0	-1.4	-1.6
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	7.8	2.8	1.0	1.5	0.4	1.0	1.2	0.8	1.5	1.7	1.0	1.4	-1.4	-1.0	0.7	0.8	-1.2	-1.1	1.1	1.1	1.4	0.4	1.0	1.3	0.8
Leg fat percentage (right)	1.0	3.7	9.9	-3.1	-1.5	-1.7	-1.9	-1.0	-1.1	-2.4	-1.8	-2.1	-2.5	-1.6	0.4	2.2	-0.5	-2.2	2.7	2.1	-1.5	-1.9	-2.5	1.3	-2.4	-1.0	-2.1
Number of full sisters	1.0	1.2	4.8	-1.2	-1.3	-1.5	-1.6	-0.4	-1.4	-0.9	-1.1	-0.9	-0.9	-2.2	1.0	1.1	0.0	-0.6	1.1	1.1	-1.2	-1.0	-1.1	-0.2	-0.6	-1.1	-0.8
Leg fat-free mass (right)	1.0	5.4	9.7	-3.1	-1.8	-2.1	-0.8	-2.3	-2.2	-2.5	-2.5	-2.7	-3.1	-2.7	1.5	1.7	-1.6	-2.9	3.0	2.4	-2.1	-2.7	-2.7	-0.7	-2.3	-1.8	-2.7
Illnesses of father: High blood pressure	1.0	1.3	6.3	0.3	-1.1	-1.4	-2.0	-1.6	-0.9	-0.6	-0.5	-1.2	-0.5	-2.5	1.5	1.1	-0.9	-1.0	0.9	0.7	-0.9	-0.8	-0.6	-1.0	-0.8	-1.0	-0.8
Basal metabolic rate	1.0	5.3	8.4	-2.7	-1.9	-2.2	-1.6	-2.3	-2.1	-2.4	-2.4	-2.7	-2.9	-2.9	1.5	2.0	-1.5	-2.8	2.9	2.3	-2.0	-2.5	-2.7	-0.4	-2.4	-1.7	-2.6
Fractured/broken bones in last 5 years	1.0	1.3	3.5	0.1	-1.0	-1.1	-1.9	-1.4	-0.8	-0.9	-0.8	-1.6	-1.0	-1.7	0.2	1.5	-0.4	-1.3	1.0	1.0	-1.0	-1.1	-0.9	-1.0	-1.4	-0.8	-1.3
LDL Cholesterol	0.9	1.5	2.6	-1.3	-1.5	-0.6	0.1	-1.1	-1.5	-1.6	-1.3	-0.7	-1.3	-0.5	1.3	1.3	-0.2	-1.5	1.4	1.5	-1.1	-1.3	-1.5	-0.6	-1.5	-1.2	-1.5
Number of treatments/medications taken	0.9	1.6	3.5	-1.5	-1.0	-1.6	0.4	-1.2	-0.5	-1.1	-0.9	-1.2	-1.3	-0.9	-0.4	1.9	-1.5	-1.7	1.4	1.4	-1.1	-1.3	-1.5	-0.3	-1.8	-1.3	-1.5
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.7	-0.2	-1.0	-0.9	-1.6	-1.0	-0.7	-0.7	-1.0	-1.6	-1.3	-1.4	0.9	0.3	-1.2	-1.0	0.9	0.8	-1.0	-1.0	-1.0	0.0	-0.8	-1.0	-0.8
Impedance of arm (left)	0.9	4.2	7.5	-1.9	-2.0	-1.5	0.9	-1.9	-2.1	-2.6	-2.2	-1.4	-2.5	-0.6	1.6	0.1	-2.1	-2.3	2.4	2.7	-2.1	-2.5	-2.2	-2.0	-1.7	-2.6	-2.5
Exposure to tobacco smoke outside home	0.9	1.2	2.8	-0.1	-1.0	-0.9	0.4	-1.3	0.0	-0.8	-1.3	-0.6	-1.0	-1.5	1.6	0.6	-0.7	-1.3	0.9	1.1	-1.5	-1.4	-1.1	-1.6	-0.8	-1.7	-1.3
Qualifications: nursing, teaching	0.9	1.4	6.6	0.5	-1.4	-0.6	-2.6	-0.8	-1.2	-0.8	-0.7	-0.4	-0.7	-0.6	-0.8	0.6	-1.6	-1.1	1.3	1.2	-0.8	-1.3	-0.7	-2.0	-1.0	-1.3	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	3.2	-0.4	-1.2	-1.1	-0.7	-0.7	-0.3	-0.7	-0.9	-0.9	-0.8	-1.2	1.4	1.8	-1.0	-0.8	1.1	1.3	-1.2	-0.9	-1.2	-0.3	-1.3	-1.2	-0.9
Medication: Aspirin	0.9	1.1	4.4	-0.4	-0.8	-1.4	-2.1	-1.7	-0.5	-0.5	-0.7	-1.2	-0.8	-1.2	-0.0	1.4	-0.8	-1.1	0.8	0.9	-1.0	-0.9	-1.0	-0.7	-1.4	-1.0	-1.0
Illnesses of father: None of the above (group 1)	0.9	1.1	2.9	0.4	1.0	1.4	1.6	1.3	1.1	0.7	0.8	0.9	0.8	1.4	-0.7	-1.7	1.4	0.5	-1.1	-1.0	0.7	0.9	0.9	1.3	1.3	0.9	0.6
Average weekly beer plus cider intake	0.9	1.3	5.3	2.0	0.6	1.0	2.3	-0.1	1.9	0.9	1.4	0.8	1.2	0.9	-0.7	0.2	1.1	0.9	-0.9	-0.8	1.4	1.2	1.0	0.0	0.5	1.2	1.0
Commuting to job workplace: Cycle	0.9	1.1	6.6	1.2	0.6	0.6	2.5	0.7	2.6	1.1	1.0	1.1	0.8	0.8	-0.3	-1.3	0.9	0.5	-0.8	-0.7	0.4	0.6	0.5	1.1	0.8	-0.0	0.6
Rheumatoid Arthritis	0.8	1.1	4.4	-1.0	-1.0	-0.8	0.1	-1.0	-1.2	-1.0	-0.9	-1.2	-1.1	-1.5	2.1	1.0	-0.8	-1.1	0.8	0.8	-0.8	-0.8	-1.0	-0.7	-1.0	-0.9	-0.9
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.0	-1.7	-0.2	-1.2	-1.7	-1.0	-1.1	-1.2	-0.7	-0.3	-0.8	-0.6	0.0	0.9	-1.5	-0.8	1.4	0.4	-0.9	-1.0	-0.7	-0.9	-0.6	-0.4	-0.8
Heel T-Score	0.8	6.1	19.4	3.3	2.3	3.0	-0.0	3.6	1.6	1.6	2.4	2.6	1.8	2.3	-2.6	-2.0	3.6	1.5	-1.4	-2.0	2.6	2.3	1.7	4.4	1.7	3.2	1.6
Relative age of first facial hair	0.8	1.5	3.7	-1.9	-1.0	-1.3	-0.3	-1.3	-0.8	-0.7	-1.3	-1.4	-1.7	-0.5	0.7	-0.1	-1.3	-1.4	1.4	1.1	-1.5	-1.6	-1.1	-1.9	-1.0	-1.3	-1.2
Current tobacco smoking	0.8	1.2	2.1	-0.9	-1.2	-1.3	1.1	-1.5	-0.8	-0.9	-1.0	-0.9	-1.3	-1.2	1.1	0.6	0.2	-1.0	1.1	1.3	-1.3	-1.3	-1.2	-1.4	-0.9	-1.4	-0.9
Age when periods started (menarche)	0.8	1.9	3.8	-0.4	-1.5	-1.0	-1.7	-1.3	-1.2	-1.8	-1.5	-1.4	-1.9	-2.0	0.8	0.7	-1.0	-1.2	1.6	1.5	-1.5	-1.6	-1.6	-0.7	-1.3	-1.3	-1.4
Chronic bronchitis/emphysema (father)	0.8	0.9	3.2	0.3	-0.7	-1.4	-0.5	-1.3	-1.2	-0.6	-0.4	-0.8	-0.5	-1.3	0.7	1.8	-1.2	-0.6	0.9	0.8	-0.6	-0.8	-0.8	-1.4	-1.0	-0.8	-0.8
Hair/balding pattern: Pattern 3	0.8	1.2	5.1	1.5	0.8	0.7	1.6	0.5	2.3	0.3	1.3	1.6	1.1	0.4	-1.0	-0.9	0.2	1.0	-1.0	-1.2	0.8	1.0	0.9	1.0	1.0	1.1	1.1
Medication: Aspirin	0.8	1.0	5.8	-0.3	-0.6	-1.4	-2.4	-1.6	-0.2	-0.4	-0.6	-1.2	-0.6	-1.0	-0.4	1.4	-0.5	-0.9	0.7	0.8	-1.0	-0.8	-0.8	-0.7	-1.2	-1.0	-0.8
Breast cancer (self-reported)	0.8	1.0	2.9	-1.5	-0.3	-0.9	-1.6	-0.8	-1.6	-1.1	-0.6	-0.9	-0.7	-0.1	0.4	1.0	-1.7	-0.9	1.0	0.7	-0.8	-0.8	-0.6	-1.3	-1.0	-0.1	-0.8
Average weekly champagne plus white wine intake	0.8	1.1	4.0	0.8	0.6	1.3	0.5	1.5	1.0	0.8	0.6	1.2	0.7	1.5	-1.2	-0.5	1.3	0.9	-0.7	-0.8	0.7	1.0	0.6	2.0	0.6	1.2	0.9
Arm fat-free mass (left)	0.8	4.1	8.8	-2.2	-1.7	-2.2	-1.6	-2.1	-1.6	-2.0	-2.1	-2.6	-2.3	-3.0	1.4	2.2	-1.2	-2.4	2.4	1.9	-1.9	-2.1	-2.3	-0.2	-2.1	-1.5	-2.1
Diastolic blood pressure, automated reading	0.8	2.5	4.4	0.9	1.4	1.7	1.4	2.1	1.4	1.6	1.5	1.5	1.6	0.6	-1.3	-0.4	2.0	1.9	-1.6	-1.9	1.6	1.9	1.6	1.4	1.3	2.1	1.9
Arm predicted mass (left)	0.8	4.3	9.7	-2.2	-1.9	-2.2	-1.9	-2.0	-1.6	-2.0	-2.1	-2.6	-2.4	-3.1	1.4	2.2	-1.0	-2.3	2.4	1.9	-2.0	-2.1	-2.4	-0.2	-2.2	-1.6	-2.2
Lupus	0.7	1.1	2.6	0.1	1.1	1.2	0.4	0.9	0.2	1.0	0.8	1.0	1.0	1.2	-1.5	-1.5	1.4	1.0	-1.0	-0.8	1.1	1.0	1.3	0.6	1.6	1.1	1.0
Triglycerides	0.7	1.2	3.1	-0.2	-1.2	-0.8	-0.3	-0.7	-1.7	-1.0	-0.8	-1.1	-1.5	-1.0	0.0	1.4	-0.3	-1.4	1.8	1.4	-0.5	-1.2	-1.3	-0.7	-1.3	-0.6	-1.4
BMI	0.7	3.8	9.7	-3.1	-1.0	-1.9	-2.3	-1.2	-1.7	-2.1	-1.6	-2.6	-2.4	-1.8	0.8	2.3	-1.3	-2.3	2.8	1.9	-1.2	-1.9	-2.3	0.8	-2.3	-0.4	-2.1
Sensitivity / hurt feelings	0.7	1.2	3.6	1.1	1.0	1.0	1.9	0.9	0.9	1.0	0.9	1.4	1.0	0.7	-0.6	-1.2	1.1	1.2	-1.2	-1.1	0.8	1.1	1.1	1.1	1.2	1.0	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	3.8	0.2	1.4	1.6	1.0	1.8	1.2	1.2	1.3	1.2	0.9	1.6	-1.5	-1.5	0.6	1.1	-1.1	-1.3	1.4	1.3	1.1	1.9	1.1	1.6	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.3	0.3	1.5	0.5	-0.1	0.5	1.3	0.7	0.9	0.5	0.8	1.2	-1.0	-1.5	1.5	0.7	-1.0	-1.2	0.3	0.7	0.9	0.3	1.2	0.9	0.9
Exposure to tobacco smoke at home	0.7	0.8	3.0	0.0	-1.1	-0.4	0.2	-0.5	0.1	-1.0	-0.9	-0.9	-1.2	-1.7	1.3	0.4	-0.5	-0.9	0.9	1.0	-0.7	-1.0	-1.1	-0.3	-0.7	-0.9	-0.9
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.6	-0.3	0.9	0.7	0.9	0.4	0.8	1.6	0.9	0.9	0.7	1.3	-1.2	-1.1	0.5	1.1	-0.7	-0.7	0.9	0.7	1.1	-0.7	1.2	0.7	1.1
Medication: Paracetamol	0.7	1.2	3.3	-1.8	-0.1	-1.6	-1.2	-1.3	-1.1	-0.2	-0.7	-1.0	-1.0	-0.7	-0.7	1.7	-1.6	-1.0	1.0	0.7	-0.9	-0.9	-0.7	-1.8	-1.2	-0.9	-0.8
Medication: Amlodipine	0.7	1.0	1.7	-0.3	-1.0	-1.1	0.6	-1.3	-0.6	-1.2	-0.7	-1.2	-0.8	-1.0	0.9	1.3	-0.5	-1.2	0.8	1.1	-1.1	-0.9	-1.3	0.6	-1.3	-0.9	-1.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.4	-1.1	-0.6	-1.3	-1.6	-1.5	-0.2	-0.2	-0.5	-0.9	-0.9	-0.9	0.1	0.4	-1.0	-0.6	0.7	0.7	-1.1	-0.8	-0.6	-1.3	-0.5	-0.9	-0.5
Suffer from ‘nerves’	0.7	1.0	4.8	1.0	1.1	1.2	1.2	0.6	0.9	0.9	1.1	0.7	0.8	1.5	-1.0	-2.2	1.2	0.4	-0.9	-1.0	0.6	0.7	1.0	0.3	1.2	0.5	0.7
Had major operations	0.7	0.8	1.5	-1.1	-0.7	-1.1	-0.9	-0.7	-1.1	-1.2	-1.0	-1.0	-0.7	-1.2	1.0	0.9	-0.7	-1.0	0.7	0.8	-0.9	-0.7	-1.0	0.4	-0.8	-0.9	-0.9
Whole body fat-free mass	0.7	4.1	7.3	-2.1	-1.7	-1.9	-1.3	-2.1	-1.8	-2.0	-2.1	-2.4	-2.5	-2.7	1.4	1.8	-1.3	-2.5	2.5	2.0	-1.8	-2.2	-2.4	-0.3	-2.1	-1.5	-2.3
Diabetes diagnosed by doctor	0.7	1.1	3.5	-1.4	-0.6	-1.1	-1.9	-0.3	-1.2	-0.5	-0.9	-0.8	-1.3	-1.0	0.4	1.0	-1.8	-1.0	1.3	1.0	-0.7	-1.1	-1.0	-0.6	-1.0	-0.4	-0.9
Whole body water mass	0.7	4.2	7.1	-2.3	-1.7	-2.0	-1.5	-2.1	-1.9	-2.0	-2.2	-2.5	-2.6	-2.7	1.3	1.8	-1.4	-2.5	2.6	2.0	-1.8	-2.2	-2.4	-0.4	-2.1	-1.5	-2.3
Supplements: Fish oil (including cod liver oil)	0.7	1.0	4.8	-0.8	-0.7	-1.1	-2.2	-0.7	-2.0	-0.6	-0.7	-1.0	-0.4	-0.8	1.1	1.4	-0.7	-0.9	0.8	1.0	-0.5	-0.5	-0.9	0.4	-0.9	-0.5	-1.0
Ever smoked	0.7	1.3	5.3	1.5	1.2	1.4	1.4	1.7	0.8	0.8	0.7	0.7	0.8	0.6	-0.5	-0.7	2.3	0.7	-0.8	-1.0	0.5	0.9	0.7	1.9	0.8	1.5	0.9
Alcohol drinker status: Previous	0.7	0.8	2.8	-0.7	-0.6	-0.9	0.4	-0.3	-0.9	-1.1	-0.6	-1.0	-0.9	-1.3	1.1	0.7	-1.7	-1.1	1.3	0.8	-0.7	-1.0	-1.0	-0.1	-0.7	-0.5	-1.0
Prostate Cancer	0.6	0.9	2.5	0.8	0.7	1.1	0.5	0.9	1.3	0.9	0.8	1.4	1.1	1.6	-1.2	-0.6	0.5	1.1	-1.1	-0.7	0.7	0.8	0.8	0.2	0.8	0.7	0.9
Medication: Co-codamol	0.6	0.7	2.8	-1.7	-0.9	-1.0	1.1	-0.6	-0.6	-0.1	-0.6	-0.6	-0.1	-1.2	1.6	0.4	-1.1	-0.1	0.3	0.7	0.1	-0.5	-0.2	-1.3	-0.1	-1.2	-0.2
Medication: Metformin	0.6	0.9	2.1	-1.2	-0.7	-1.0	-1.4	-0.7	-0.6	-0.7	-0.9	-0.8	-1.1	-0.6	0.5	0.9	-1.4	-1.0	1.0	1.0	-0.8	-1.0	-0.9	-1.1	-1.1	-1.0	-1.0
Medication: Atenolol	0.6	0.8	4.2	1.4	1.1	0.3	-0.7	0.5	0.4	0.9	1.1	0.4	0.8	0.6	-1.3	-0.2	0.6	0.6	-0.5	-0.9	0.6	0.8	0.4	2.0	0.4	1.0	0.7
Sitting height	0.6	4.0	7.1	-1.9	-1.6	-1.7	-0.9	-2.7	-2.5	-1.8	-2.0	-2.1	-2.1	-2.3	2.1	0.5	-2.2	-2.5	2.0	2.0	-1.9	-2.3	-1.9	-2.1	-1.3	-1.9	-2.3
Allergy	0.6	1.3	5.0	-0.4	-0.8	-1.4	-2.2	-1.5	-1.0	-0.3	-1.0	-1.3	-0.9	-0.7	1.0	1.1	-1.9	-1.0	1.1	1.0	-1.2	-1.2	-0.9	-1.4	-1.1	-0.7	-1.1
Trunk fat-free mass	0.6	3.4	6.7	-1.6	-1.6	-1.9	-1.5	-2.0	-1.7	-1.7	-1.9	-2.3	-2.1	-2.6	1.3	1.8	-1.4	-2.2	2.1	1.8	-1.7	-1.9	-2.1	-0.4	-1.9	-1.4	-2.0
Trunk predicted mass	0.6	3.3	6.4	-1.6	-1.6	-1.8	-1.6	-2.0	-1.7	-1.7	-1.9	-2.2	-2.1	-2.5	1.3	1.8	-1.4	-2.2	2.1	1.7	-1.6	-1.8	-2.0	-0.3	-1.9	-1.3	-2.0
Breastfed as a baby	0.6	0.8	3.8	0.9	-0.0	0.8	0.6	1.2	1.4	0.4	0.3	0.8	0.3	0.8	-0.3	-2.0	1.8	0.5	-0.4	-0.4	0.6	0.3	0.3	1.3	1.1	0.5	0.3
Loud music exposure frequency	0.6	0.7	2.7	-1.2	-0.3	-1.1	-0.5	-0.5	-1.0	-0.9	-1.1	-0.9	-0.8	-1.3	1.6	-0.1	-0.7	-0.5	0.4	0.4	-1.6	-0.6	-0.7	0.2	-0.1	-0.6	-0.4
Family relationship satisfaction	0.6	0.7	2.9	1.4	0.9	0.7	0.9	0.4	1.7	1.0	0.7	0.5	0.5	0.9	-0.7	-1.1	1.3	0.5	-0.8	-1.0	0.4	0.6	0.7	0.2	0.7	0.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.3	-1.2	-1.0	-0.6	0.9	-1.6	-1.0	-1.2	-1.0	-1.1	-1.1	-0.8	1.8	0.5	-1.7	-1.4	1.2	1.3	-0.6	-1.0	-1.3	-0.2	-0.9	-0.7	-1.4
Guilty feelings	0.6	1.0	2.2	1.3	0.9	0.6	1.5	0.2	0.8	0.5	1.1	1.0	1.1	0.8	-0.7	-1.1	1.2	1.0	-1.1	-1.0	0.9	1.0	1.2	-0.3	1.2	0.7	1.1
Commuting to job workplace: Public transport	0.6	0.7	3.0	-0.1	-1.2	-1.0	-0.8	-0.9	-1.3	-1.1	-0.7	-0.5	-0.6	-1.7	0.9	0.3	-0.6	-0.5	0.5	1.1	-0.6	-0.7	-0.7	-0.7	-0.3	-1.1	-0.7
Medication: Lisinopril	0.6	0.8	2.9	1.2	0.6	0.9	1.7	0.5	0.8	1.0	0.9	0.9	1.0	0.6	-0.4	0.3	0.3	0.4	-0.9	-0.8	1.1	1.0	0.5	1.5	0.1	1.0	0.5
Depression (Nagel 2018)	0.5	0.7	1.7	-1.0	-0.7	-0.9	0.2	-0.5	-0.7	-0.5	-0.9	-0.7	-0.8	-0.7	-0.3	0.7	-0.6	-0.9	1.3	1.2	-1.3	-1.1	-1.1	-0.5	-0.8	-1.2	-1.0
Neuroticism (2016)	0.5	0.8	2.8	0.1	1.2	0.7	0.4	1.0	0.1	0.4	0.6	1.2	0.4	0.9	-1.6	-1.1	1.0	0.7	-0.4	-0.8	0.5	0.6	0.5	1.7	0.8	1.0	0.7
Blood White Count	0.5	4.0	8.4	0.8	2.8	1.7	0.2	1.3	2.1	2.9	2.3	2.1	2.1	2.0	-1.9	-1.3	0.0	2.2	-2.1	-2.4	2.2	2.2	2.5	0.3	2.2	2.3	2.4
Neuroticism	0.5	1.1	3.2	1.1	1.2	0.6	1.8	0.8	1.2	0.6	1.2	0.7	0.7	0.5	-1.4	-1.7	1.2	1.0	-0.9	-1.1	0.4	0.8	0.8	0.9	1.4	0.7	1.1
Diabetes (father)	0.5	0.6	4.8	-1.1	-0.2	-0.7	-0.1	-1.4	-1.1	0.4	-0.6	-0.8	0.0	-0.1	0.3	0.7	-1.1	-0.5	0.4	0.5	-0.2	-0.6	-0.0	-2.2	-0.1	-0.9	-0.4
Hand grip strength (right)	0.5	1.3	6.4	1.5	1.3	0.7	-1.0	0.6	0.4	0.9	0.9	0.5	0.9	0.7	-0.6	-1.2	2.5	0.6	-1.0	-1.4	1.0	1.1	0.9	1.5	1.1	1.7	1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.2	1.0	1.1	0.2	0.5	0.5	0.9	-0.3	1.0	0.5	0.8	-0.0	-1.0	-0.2	0.6	0.8	-0.8	-1.1	0.4	0.8	0.8	0.4	0.6	1.1	0.9
Body mass index (BMI)	0.5	2.0	8.3	-2.9	-0.8	-1.3	-1.3	-0.7	-0.8	-1.6	-1.2	-1.7	-1.9	-1.4	0.1	1.6	-0.4	-1.6	2.0	1.3	-0.9	-1.4	-1.7	0.9	-1.6	-0.5	-1.4
Forced vital capacity (FVC)	0.5	1.9	4.2	1.3	2.1	1.6	0.9	0.7	1.0	1.7	1.5	0.9	1.0	1.8	-1.4	-2.0	1.4	0.8	-1.2	-1.6	1.4	1.3	1.4	0.5	1.5	1.5	1.2
Diabetes (self-reported)	0.5	0.7	2.4	-1.2	-0.4	-1.0	-1.5	-0.4	-0.9	-0.4	-0.7	-0.8	-1.0	-0.6	0.3	1.0	-1.4	-0.9	1.1	0.9	-0.4	-0.9	-0.8	-0.2	-0.8	-0.1	-0.8
Medication: Ramipril	0.5	0.6	1.3	-0.3	-1.0	-0.8	-0.6	-0.7	-0.8	-0.6	-0.8	-0.6	-0.7	-0.8	0.0	0.5	-1.0	-0.6	0.6	0.9	-1.0	-0.9	-0.7	-1.1	-0.6	-1.0	-0.7
Alcohol intake versus 10 years previously	0.5	0.8	2.1	0.6	0.7	0.7	0.7	0.3	1.0	1.4	0.9	0.4	1.2	0.3	0.3	-0.1	0.4	1.0	-1.4	-1.1	1.0	1.3	1.2	0.1	0.7	1.1	1.2
Depression (self-reported)	0.5	0.6	1.7	0.4	1.3	0.5	-0.8	0.5	1.2	0.5	0.9	0.7	0.4	1.1	-1.3	-0.9	0.9	0.4	-0.2	-0.8	0.2	0.4	0.4	1.1	0.6	0.8	0.6
Arm fat-free mass (right)	0.5	2.7	7.5	-1.6	-1.2	-1.8	-1.9	-1.5	-1.5	-1.4	-1.7	-2.1	-1.9	-2.7	1.0	1.6	-1.0	-1.8	1.9	1.4	-1.5	-1.6	-1.8	-0.0	-1.6	-1.0	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	9.7	0.3	0.4	0.5	3.1	0.1	1.3	0.2	0.1	0.3	-0.3	0.7	-0.1	-1.0	0.6	-0.3	0.5	0.1	-0.2	-0.3	-0.3	0.8	0.1	-0.1	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	4.0	1.3	-0.3	0.5	2.0	0.2	1.9	0.4	0.3	0.2	0.1	-0.2	-0.3	-0.6	1.3	0.0	0.1	0.0	0.2	0.0	-0.2	0.8	0.1	-0.2	-0.1
Medication: Allopurinol	0.5	0.7	1.7	0.7	1.1	0.2	0.2	0.6	1.1	0.7	0.9	0.4	0.9	0.2	-0.4	-0.4	1.3	1.0	-0.8	-1.0	1.0	0.9	1.0	0.4	0.9	0.9	1.1
Arm predicted mass (right)	0.5	2.7	6.4	-1.7	-1.3	-1.7	-1.8	-1.5	-1.3	-1.5	-1.7	-2.2	-2.1	-2.5	0.8	1.5	-0.9	-1.9	2.0	1.5	-1.5	-1.7	-1.9	0.1	-1.7	-1.0	-1.7
Mineral and other dietary supplements	0.5	0.7	2.0	0.9	0.6	0.9	1.4	0.9	1.3	0.4	0.7	0.9	0.7	-0.1	-0.5	-0.9	1.4	0.6	-0.9	-0.9	0.5	0.7	0.8	0.4	0.8	0.5	0.8
Hearing aid user	0.5	0.6	2.5	-0.3	-0.9	-0.9	-0.4	-1.1	-0.6	0.0	-0.7	-0.6	-0.3	-0.6	0.6	1.4	-0.5	-0.4	0.4	0.7	-0.6	-0.5	-0.5	-1.6	-1.0	-1.1	-0.3
Age started oral contraceptive pill	0.5	0.7	2.7	-0.8	-0.8	-0.6	-0.2	-0.1	-0.1	-0.9	-0.5	-0.8	-1.0	-0.5	-0.2	0.5	-1.6	-1.1	1.1	0.8	-0.7	-0.9	-0.9	-0.5	-1.1	-0.6	-1.1
Impedance of whole body	0.5	2.3	5.1	-1.0	-1.7	-1.2	0.3	-1.5	-1.4	-1.9	-1.6	-1.0	-1.6	-0.7	1.4	0.1	-1.6	-1.5	1.5	2.1	-1.8	-1.9	-1.6	-1.9	-1.1	-2.2	-1.7
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.8	-0.3	-1.2	-0.7	0.3	-0.7	-1.9	-1.1	-1.0	-0.6	-1.2	-0.6	-0.0	2.2	-1.1	-1.1	1.6	1.5	-0.9	-1.1	-1.2	-0.5	-1.5	-1.0	-1.4
Worry (Nagel 2018)	0.4	0.9	3.5	1.0	1.1	1.1	0.9	0.9	0.6	1.0	1.1	0.9	0.8	0.9	-1.3	-1.9	1.1	0.9	-1.0	-0.9	0.3	0.7	0.9	-0.0	1.3	0.5	0.9
Body Mass Index (BMI) (2010)	0.4	0.5	1.7	-0.7	-0.1	-0.2	0.2	-0.9	-0.5	-0.7	-0.4	-0.9	-0.7	-0.4	1.2	0.3	-0.2	-1.1	1.3	0.5	-0.5	-0.9	-0.7	-0.2	-0.7	0.3	-1.0
Blood Eosinophil Count	0.4	3.1	6.3	2.5	1.9	2.2	1.3	1.6	1.2	1.8	1.9	1.4	1.8	1.5	-1.5	-1.7	1.5	1.6	-1.7	-1.8	2.1	1.9	1.5	2.0	1.4	2.0	1.7
Chronotype (morning person)	0.4	0.8	3.1	0.5	-1.0	-0.8	-1.4	-1.3	-1.4	-0.8	-0.4	-1.3	-1.1	-1.8	0.3	0.6	-0.6	-1.0	0.8	0.7	-0.2	-0.7	-0.7	-0.1	-0.7	-0.2	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.4	1.4	-0.2	0.7	0.2	-0.2	1.1	0.5	0.0	0.5	0.7	0.5	0.4	-0.7	-0.3	1.2	0.8	-0.6	-0.8	0.0	0.6	0.4	1.2	0.4	1.1	0.9
Multivitamins +/- minerals	0.4	0.5	3.0	-0.7	0.8	0.5	0.5	0.2	0.8	0.5	0.8	0.5	0.2	1.1	-0.8	-1.7	0.5	0.4	-0.4	-0.5	0.7	0.4	0.5	0.1	1.1	0.3	0.4
Financial difficulties in last 2 years	0.4	0.5	3.8	-0.4	-0.8	-0.6	0.9	-0.6	-0.2	-0.6	-0.6	-1.0	-0.5	-1.0	2.0	-0.1	0.4	-0.8	0.3	0.5	-0.5	-0.6	-0.5	-0.4	-0.5	-1.0	-0.5
Heart attack	0.4	0.5	3.5	-1.0	-0.0	-0.7	-1.9	-1.1	-0.5	-0.1	-0.6	-0.5	-0.6	-0.6	1.1	-0.3	0.1	-0.3	0.4	0.3	-0.8	-0.5	-0.7	-0.3	-0.2	-0.8	-0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	0.7	0.6	1.1	0.9	1.0	0.1	0.4	0.6	1.2	0.5	0.7	-0.6	-0.6	0.7	0.4	-0.4	-0.6	0.9	0.7	0.7	1.0	0.7	0.8	0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.3	2.1	0.5	1.9	-0.3	0.3	0.6	0.4	1.3	1.3	0.9	1.6	-1.4	-0.7	-0.3	0.3	-0.5	-0.5	1.0	0.6	0.9	-0.2	0.5	0.4	0.1
Medication: Cholesterol lowering	0.4	0.6	1.7	0.4	-1.0	-0.6	-1.1	-0.8	-0.3	-0.5	-0.6	-0.5	-0.6	-1.2	0.6	1.3	0.1	-0.7	0.6	0.9	-0.5	-0.6	-0.9	-0.2	-1.1	-0.8	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.3	0.6	1.8	1.4	0.9	0.1	0.9	1.5	1.2	0.5	0.9	2.1	-0.8	-1.8	0.8	0.5	-0.8	-1.2	1.4	0.9	1.1	-0.1	1.2	1.1	0.8
Blood clot in the leg (DVT)	0.4	0.5	1.6	0.1	-1.1	-0.9	0.1	-0.3	-0.0	-0.6	-0.5	-1.2	-0.6	-1.0	0.4	1.1	0.2	-0.9	0.6	0.8	-0.5	-0.6	-0.8	0.0	-0.7	-0.9	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	3.0	-0.7	1.2	0.5	-0.4	0.9	-0.3	0.2	0.2	0.2	0.4	1.7	-0.2	-1.6	1.0	0.6	-0.4	-0.8	0.4	0.5	0.7	0.4	1.1	0.8	0.6
Forced vital capacity (FVC), Best measure	0.4	1.5	4.0	0.8	2.0	1.5	1.2	0.7	1.0	1.7	1.3	0.8	0.8	2.0	-1.1	-2.0	1.2	0.7	-0.8	-1.2	1.2	0.9	1.0	0.5	1.4	1.2	0.9
Medication: Blood pressure	0.4	0.6	3.6	0.9	-1.1	-0.5	0.7	-1.1	-0.1	-0.1	0.0	-0.3	-0.4	-1.9	0.2	1.5	-1.6	-0.6	0.3	0.6	-0.2	-0.3	-0.6	-0.1	-0.9	-0.4	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.4	1.2	0.3	0.9	0.0	0.2	0.4	0.3	0.6	0.2	0.6	0.5	-1.0	-0.1	0.6	0.4	-0.7	-0.7	1.0	0.9	0.6	1.0	0.2	0.9	0.5
Overall health rating	0.4	0.9	4.8	-0.1	-1.0	-0.8	2.2	-1.2	-0.4	-0.6	-1.0	-0.8	-0.9	-1.0	1.4	0.5	0.5	-0.8	0.3	0.9	-0.7	-0.8	-0.9	-0.7	-0.8	-1.2	-0.6
Age at last live birth	0.4	0.6	3.1	1.4	0.1	1.0	-0.1	1.2	0.6	0.1	0.4	0.5	0.3	0.6	-0.3	-1.3	1.8	0.4	-0.5	-0.5	0.7	0.5	0.4	1.4	0.7	0.5	0.4
Mood swings	0.4	0.7	1.9	1.2	0.8	0.7	1.3	0.6	1.2	0.6	0.8	0.4	0.6	0.5	-0.9	-1.4	1.3	0.5	-1.0	-0.8	0.5	0.6	0.7	0.4	0.9	0.4	0.7
Eye problems/disorders: Cataract	0.4	0.5	1.0	0.1	-0.6	-0.7	-0.6	-0.4	-0.7	-0.6	-0.7	-0.8	-0.7	-0.1	0.0	0.4	-0.8	-1.0	0.9	0.8	-0.5	-0.9	-0.8	-0.2	-0.8	-0.7	-1.0
Back pain experienced in last month	0.4	0.6	1.5	0.4	0.8	-0.1	0.2	-0.5	1.0	0.6	0.7	0.7	0.8	0.3	-1.0	-0.8	1.1	0.7	-1.2	-1.0	-0.1	0.5	1.1	-1.2	1.1	0.2	1.0
High cholesterol (Self-reported)	0.4	0.7	3.8	-0.8	-0.8	-0.6	-1.1	-0.8	-0.4	-0.6	-0.9	-0.4	-0.6	-0.8	0.4	1.9	-0.8	-0.4	0.4	0.7	-0.6	-0.5	-0.7	-1.1	-1.4	-0.8	-0.4
Medication: Paracetamol	0.4	0.6	2.5	-0.9	-0.1	-1.1	-0.3	-1.2	-0.2	-0.0	-0.3	-0.7	-0.5	-0.5	-0.5	1.6	-1.0	-0.8	0.7	0.5	-0.4	-0.5	-0.5	-1.2	-1.0	-0.5	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.1	0.5	0.2	0.5	-0.6	0.6	0.2	0.3	0.5	0.7	0.5	0.3	0.2	-0.9	1.0	1.0	-0.8	-0.6	0.8	0.8	0.6	0.6	0.8	0.5	0.9
Pain experienced in last month	0.4	0.6	3.4	0.5	0.4	1.5	-0.2	1.5	0.1	0.4	0.4	0.9	0.5	1.1	0.6	-0.9	0.2	0.6	-0.3	-0.4	0.8	0.7	0.3	1.9	0.4	1.0	0.4
Supplements: Calcium	0.4	0.4	2.2	0.3	0.6	0.1	0.6	-0.4	0.8	0.8	0.5	0.4	0.3	0.6	-0.7	-1.2	-0.4	0.5	-0.4	-0.5	0.1	0.1	0.8	-1.5	1.0	0.1	0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.1	-1.2	-0.1	-0.7	-1.8	-1.1	-0.5	-0.1	-0.7	-0.5	-0.6	-0.5	1.0	-0.4	-0.0	-0.3	0.4	0.4	-0.8	-0.6	-0.6	-0.6	-0.2	-0.8	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.9	0.0	-1.0	-1.0	-0.1	-0.4	-0.1	-0.6	-0.5	-1.4	-0.6	-1.1	0.4	1.0	-0.0	-0.9	0.7	0.8	-0.4	-0.6	-0.7	-0.2	-0.7	-0.9	-0.9
Reaction Time	0.3	0.7	2.8	0.4	0.8	0.7	1.7	0.7	0.9	0.9	0.6	1.0	0.8	1.2	0.3	-1.1	0.4	0.7	-0.8	-0.7	0.5	0.7	0.8	0.4	0.8	0.4	0.8
Fasting Glucose	0.3	0.3	1.7	-1.2	-0.3	-0.7	0.7	-0.0	-0.8	-0.2	-0.1	-0.3	-0.5	-0.2	0.2	0.2	-1.0	-0.4	0.4	0.5	-0.6	-0.4	-0.0	-1.3	-0.2	-0.4	-0.5
Blood Platelet Count	0.3	3.4	13.7	-0.6	2.8	1.9	1.4	0.4	2.1	2.3	1.4	1.9	1.5	3.7	-2.4	-2.2	-0.0	1.5	-1.7	-1.9	1.3	1.5	1.9	-0.6	1.7	1.6	1.9
Allergy or Eczema	0.3	0.8	1.9	1.1	0.5	1.0	1.1	0.6	1.0	0.3	0.9	1.4	1.2	0.3	0.0	-0.6	0.9	1.2	-1.0	-0.8	0.7	1.0	0.8	0.4	1.0	0.3	1.0
Cardiovascular Disease	0.3	0.9	4.5	0.2	-0.9	-0.7	0.4	-0.7	-0.1	-0.6	-0.5	-1.2	-0.8	-1.9	0.9	2.1	-0.9	-0.8	1.0	0.9	-0.8	-0.7	-1.1	0.4	-1.5	-0.5	-0.8
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.2	0.5	0.4	0.7	0.9	1.0	0.7	1.0	0.4	0.8	0.6	0.9	-1.0	-1.1	0.9	0.5	-0.3	-0.3	0.2	0.3	0.5	0.1	0.8	0.1	0.5
Maternal smoking around birth	0.3	0.4	1.2	-0.3	-0.3	-0.3	1.0	-0.6	-0.4	-0.4	-0.3	-1.1	-0.7	-0.5	0.3	0.7	0.5	-1.1	0.6	0.5	-0.4	-0.6	-0.8	-0.2	-0.8	-0.3	-0.7
Taking other prescription medications	0.3	0.4	1.7	-1.1	-0.1	-0.8	-0.3	0.7	-0.1	-0.3	-0.4	-0.5	-0.6	-1.0	0.5	-0.2	0.1	-0.6	0.9	0.6	-0.8	-0.7	-0.8	1.3	-0.1	-0.3	-0.5
Past tobacco smoking	0.3	0.6	3.5	-0.7	-0.9	-0.7	-1.4	-1.1	-0.6	-0.0	-0.2	-0.1	-0.3	-0.1	0.0	0.0	-1.6	-0.1	0.4	0.6	-0.1	-0.5	-0.2	-1.9	-0.2	-1.2	-0.3
Alcohol usually taken with meals	0.3	0.5	6.4	0.2	-0.2	-0.6	-2.5	-0.8	0.0	-0.6	-0.4	-0.4	-0.6	0.2	-1.0	-0.3	-0.3	-0.5	0.3	0.2	-0.5	-0.5	-0.2	-1.1	-0.1	-0.5	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.1	0.9	0.7	0.0	0.7	0.6	0.2	1.0	0.6	0.7	0.8	0.5	-0.7	-1.0	1.1	0.5	-0.8	-0.7	0.5	0.5	0.8	-0.7	1.1	0.3	0.6
Had menopause	0.3	0.4	0.8	-0.7	-0.6	-0.6	-0.6	0.3	-0.3	-0.4	-0.5	-0.5	-0.8	-0.5	0.1	0.9	-0.1	-0.5	0.9	0.8	-0.7	-0.7	-0.8	0.4	-0.9	-0.1	-0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.0	0.6	0.8	0.6	0.8	0.3	0.2	0.3	0.7	0.3	0.0	0.4	-1.4	-1.0	0.5	0.5	-0.7	-0.7	0.4	0.5	0.6	0.2	0.6	0.6	0.8
Neuroticism score	0.3	0.6	1.9	1.2	0.8	0.4	1.3	0.6	0.4	0.4	0.8	0.5	0.5	0.4	-0.8	-1.4	1.4	0.5	-0.6	-0.7	0.4	0.6	0.7	0.8	1.0	0.6	0.7
Number of live births	0.3	0.5	1.6	-0.9	-0.3	-1.1	0.5	-0.9	-0.7	-0.4	-0.5	-1.3	-1.0	-1.0	-0.2	0.5	-0.2	-0.7	0.9	0.4	-0.4	-0.7	-0.6	-0.4	-0.6	-0.1	-0.3
Happiness	0.3	0.4	1.8	0.2	0.4	0.4	0.5	1.1	0.5	0.4	0.1	-0.0	-0.1	0.8	-0.2	-1.3	1.3	0.4	0.0	-0.2	-0.3	0.0	0.0	1.0	0.6	0.2	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.0	-1.0	-0.4	0.1	0.6	-0.4	0.2	-0.5	-0.6	0.2	-0.3	0.8	-0.1	-0.5	-0.6	-0.6	0.4	0.5	-0.9	-0.6	-0.3	-0.4	-0.3	-0.8	-0.6
Pulse wave Arterial Stiffness index	0.3	0.4	1.4	0.0	-0.6	-0.7	-0.2	-0.0	-1.0	-0.9	-0.5	-0.4	-0.9	-1.2	0.3	0.4	0.0	-0.4	0.6	0.5	-1.0	-0.7	-0.7	-0.2	-0.5	-0.4	-0.4
Gout (self-reported)	0.3	0.4	2.3	-0.5	-0.6	-1.1	0.0	-0.8	0.1	-0.5	-0.4	-0.8	-0.3	-1.5	0.8	0.4	-0.2	-0.3	0.3	0.3	-0.2	-0.5	-0.2	-1.0	-0.2	-0.6	-0.2
Birth weight	0.3	0.6	3.1	-0.3	-0.6	-0.9	-0.0	-1.2	-0.5	-0.3	-0.7	-0.8	-0.8	-0.5	1.8	1.2	0.1	-0.7	0.8	0.6	-0.4	-0.6	-0.9	-0.7	-1.1	-0.3	-0.7
Worry too long after embarrassment	0.3	0.4	2.8	0.1	-0.5	-0.7	-0.4	-1.5	-0.5	-0.8	-0.6	-0.5	-0.5	0.0	-0.5	0.4	-0.5	-0.4	0.3	0.5	-0.9	-0.5	-0.2	-1.7	-0.5	-0.6	-0.3
Wheeze or whistling in the chest in last year	0.3	0.5	2.1	-0.6	0.7	0.6	0.9	1.1	0.3	0.3	0.4	0.8	0.4	0.7	-0.7	-0.5	1.4	0.8	-0.4	-0.5	0.3	0.6	0.5	1.2	0.7	0.8	0.7
Emphysema/chronic bronchitis	0.3	0.3	1.6	-1.0	-0.6	-0.3	1.3	-0.1	0.5	-0.3	-0.4	-0.3	-0.0	0.1	1.1	-0.3	-0.3	-0.3	0.1	0.4	-0.4	-0.4	-0.3	-0.5	-0.2	-0.9	-0.2
Medication: Omeprazole	0.3	0.3	1.1	1.1	0.0	0.3	-0.7	0.2	0.1	-0.0	0.3	0.4	0.3	0.0	0.6	-0.4	1.0	0.7	-0.6	-0.4	0.7	0.7	0.4	0.8	0.5	0.4	0.7
Chest pain or discomfort	0.3	0.4	2.7	1.0	0.1	0.5	0.9	0.7	1.0	0.3	0.2	0.6	0.2	-0.1	-0.6	-1.0	1.6	0.5	-0.4	-0.4	0.1	0.4	0.3	0.5	0.4	-0.1	0.6
Supplements: Vitamin C	0.3	0.3	2.3	-0.5	-0.0	0.0	-1.5	-0.1	-0.4	-0.8	-0.6	-0.4	-0.8	0.5	-0.4	-0.3	0.1	-0.5	0.6	0.3	-0.7	-0.7	-0.4	-0.5	-0.3	0.0	-0.5
Ever had bowel cancer screening	0.3	0.3	2.7	-0.1	0.1	0.4	0.5	0.5	0.4	-0.3	0.3	0.0	1.1	-0.1	0.6	0.1	0.8	0.5	-0.6	-0.4	0.3	0.7	0.2	1.6	0.4	0.6	0.5
Medication for cholesterol	0.3	0.5	1.6	1.3	0.0	1.2	0.3	0.4	0.6	0.2	0.4	0.7	0.8	0.3	-0.1	-1.0	1.2	0.4	-0.6	-0.3	1.0	0.6	0.7	0.0	0.8	0.5	0.3
Smoking status: Current	0.3	0.5	1.7	-0.3	-0.6	-0.8	1.3	-0.8	-0.1	-0.4	-0.5	-0.5	-0.9	-0.7	0.7	0.1	1.0	-0.5	0.6	0.7	-0.9	-0.8	-0.8	-0.6	-0.4	-0.9	-0.4
Number of self-reported non-cancer illnesses	0.3	0.5	1.7	-1.0	-1.1	-0.5	-0.1	0.2	-0.5	-0.7	-0.7	-0.5	-0.8	-1.3	-0.2	0.3	-0.5	-0.5	0.5	0.9	-0.8	-0.6	-0.9	0.8	-0.5	-1.2	-0.6
Ever taken oral contraceptive pill	0.3	0.4	2.0	-1.3	-0.3	-0.7	0.0	-0.3	0.2	-0.2	-0.5	-0.8	-0.5	-0.7	1.4	-0.6	-0.5	-0.4	0.5	0.5	-0.8	-0.6	-0.5	0.0	0.2	-0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.3	0.0	0.7	0.0	0.8	0.0	1.1	0.5	0.6	0.4	0.7	0.6	-0.1	-0.3	0.4	0.5	-0.8	-0.7	0.6	0.5	0.7	-0.1	0.6	0.1	0.5
Myopia	0.3	0.4	2.2	-0.6	-0.2	-0.2	1.5	-1.3	0.5	-0.6	-0.7	-0.0	-0.4	-0.1	0.6	0.6	-0.8	-0.2	0.4	0.3	-1.0	-0.5	-0.5	-1.0	-0.4	-0.6	-0.3
Neuroticism (Nagel 2018)	0.2	0.5	1.8	0.8	0.7	0.5	0.4	0.6	0.3	0.8	0.6	0.6	0.6	0.4	-1.1	-1.4	0.9	0.8	-0.7	-0.6	0.2	0.4	0.5	0.1	1.0	0.2	0.7
Major Depression (MDD)	0.2	0.3	2.3	-0.5	-0.0	-0.1	0.7	0.7	0.1	0.1	-0.1	0.1	-0.3	-0.5	-0.4	-0.5	1.1	0.2	0.3	0.0	-0.5	0.0	-0.2	1.5	0.3	0.1	0.3
Smoking Status	0.2	0.5	2.6	-0.7	0.1	-0.5	1.6	0.1	-0.8	-1.0	-0.6	-0.6	-0.9	-0.8	1.0	0.3	0.9	-0.7	0.8	0.4	-0.9	-0.7	-0.7	0.0	-0.4	-0.1	-0.5
Hearing difficulty/problems: Yes	0.2	0.3	1.4	-0.3	-0.2	-0.6	1.0	-0.9	-0.7	0.4	-0.2	-0.3	0.5	-0.2	1.0	1.2	-0.4	-0.1	-0.1	0.1	0.2	0.1	-0.1	-0.6	-0.1	-0.2	-0.1
Ever had hysterectomy (womb removed)	0.2	0.3	2.8	0.0	0.6	0.0	-0.6	-0.6	-0.5	-0.4	0.2	-0.1	0.1	0.4	-0.2	0.5	-0.6	-0.1	-0.1	-0.4	0.4	0.1	0.5	-1.7	-0.3	0.6	0.3
Pack years adult smoking proportion	0.2	0.4	1.5	0.4	-0.3	-0.9	-1.2	-1.1	-0.1	0.4	-0.2	-0.5	-0.3	-0.2	0.6	0.6	0.4	-0.8	0.6	0.6	-0.6	-0.5	-0.6	0.1	-0.8	-0.6	-0.6
Average weekly fortified wine intake	0.2	0.2	0.9	-0.3	-0.6	-0.3	-0.5	-0.6	-0.1	-0.0	-0.5	-0.3	0.0	-0.4	0.7	0.4	-0.2	-0.4	0.7	0.7	-0.4	-0.5	-0.4	-0.3	-0.3	-1.0	-0.7
Fed-up feelings	0.2	0.3	1.5	0.6	0.6	0.1	0.2	0.6	0.3	0.2	0.6	0.2	0.4	0.0	-0.7	-1.2	0.8	0.8	-0.5	-0.4	0.5	0.4	0.5	0.1	1.0	0.2	0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.1	-0.9	-0.2	-0.6	0.1	-0.6	-0.1	-0.0	-0.2	-0.3	-0.4	0.0	-0.1	0.2	-0.7	-0.5	0.7	0.3	-0.2	-0.6	-0.3	-1.0	-0.3	-0.6	-0.5
High blood pressure	0.2	0.6	3.9	1.4	-0.4	-0.3	1.4	-0.3	0.7	0.1	0.4	-0.1	-0.1	-1.9	-0.1	2.0	-0.9	0.1	-0.2	-0.2	-0.1	0.3	-0.3	0.9	-0.8	0.5	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.0	0.5	0.3	0.9	1.4	0.6	0.3	-0.2	0.5	1.0	0.8	0.0	0.2	-0.7	1.0	0.7	-0.6	-0.5	0.6	0.6	0.5	0.3	0.8	0.1	0.6
Supplements: Glucosamine	0.2	0.3	2.0	-1.4	0.1	-0.2	-0.7	-0.5	0.1	-0.0	-0.4	-0.0	-0.1	0.7	-0.2	0.2	-1.3	0.3	-0.2	-0.0	0.1	0.0	0.2	-0.9	-0.1	-0.3	0.1
Number of incorrect matches in round	0.2	0.3	2.9	0.7	-0.0	0.2	1.7	0.7	0.9	-0.4	0.1	0.4	0.5	-0.4	0.6	0.1	-0.5	0.4	-0.2	-0.1	0.2	0.3	0.1	0.4	0.2	0.2	0.3
Hair/balding pattern: Pattern 2	0.2	0.3	1.2	-0.2	0.8	0.3	1.1	0.1	0.1	0.6	0.3	-0.2	0.1	1.1	-0.8	-0.3	0.7	-0.1	-0.0	-0.2	-0.1	0.2	0.1	1.0	0.0	0.2	0.0
Qualifications: None of the above	0.2	0.5	5.3	-2.3	0.1	-1.0	0.9	-0.4	-0.4	-0.4	-0.6	-0.9	-0.5	-0.4	1.0	0.0	0.1	-0.4	0.4	0.2	-0.3	-0.3	-0.8	1.2	-0.2	0.1	-0.2
Father’s age at death	0.2	0.3	0.9	0.5	-0.5	-0.1	-0.2	0.1	0.6	-0.2	-0.2	-0.2	-0.6	-0.7	-0.8	0.1	-0.9	-0.6	0.9	0.6	-0.5	-0.8	-0.8	0.4	-0.5	-0.5	-0.8
Worrier / anxious feelings	0.2	0.4	1.7	0.9	0.7	0.3	-0.2	0.5	0.4	0.6	0.6	0.5	0.3	0.1	-0.7	-1.0	1.3	0.7	-0.7	-0.7	-0.2	0.4	0.5	0.3	0.8	0.4	0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.8	0.5	1.4	1.1	0.2	-0.3	0.4	1.0	0.9	0.0	0.5	1.3	-0.8	-1.1	0.6	0.1	-0.6	-1.0	0.9	0.6	0.8	-0.4	0.8	1.0	0.5
Pulse rate	0.2	0.3	2.1	-1.5	0.6	-0.2	-0.3	-0.1	0.2	0.2	-0.3	-0.2	0.4	1.0	-0.2	0.0	-1.1	0.4	-0.4	-0.4	-0.5	0.2	0.3	-0.5	0.3	0.3	0.4
Medication: Lansoprazole	0.2	0.2	1.0	0.4	0.2	0.0	-0.1	0.4	1.0	0.6	0.9	0.2	0.2	0.5	-1.0	-0.7	0.2	0.3	-0.3	-0.3	0.4	0.3	0.5	-0.2	0.4	0.3	0.3
Lung cancer (father)	0.2	0.3	0.9	-0.3	0.3	-0.1	-0.2	0.9	0.2	0.3	0.7	-0.1	0.4	0.2	-0.2	-0.4	0.1	0.4	-0.5	-0.5	0.8	0.6	0.5	1.0	0.8	0.7	0.3
Tense / ‘highly strung’	0.2	0.3	0.9	0.7	-0.8	-0.5	0.4	-0.4	-0.2	-0.3	-0.4	-0.4	-0.6	0.1	-0.3	-0.5	-0.3	-0.6	0.5	0.6	-0.6	-0.6	-0.4	-0.7	-0.4	-0.9	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.8	-0.5	0.2	0.3	1.4	-0.3	-0.2	-0.5	-0.1	-0.0	-0.9	0.4	-0.5	-0.6	0.8	-0.3	0.6	0.4	-0.8	-0.7	-0.6	-0.3	-0.3	-0.7	-0.4
Birth weight of first child	0.2	0.4	3.1	0.6	-0.1	0.7	1.3	-0.5	1.8	0.8	-0.0	0.0	-0.3	0.2	0.9	-0.4	0.6	-0.4	0.1	-0.1	0.0	-0.1	-0.3	-0.2	-0.3	-0.0	-0.2
Peak expiratory flow (PEF)	0.2	0.4	1.3	0.6	0.7	0.8	-0.8	-0.2	-0.6	0.0	0.6	-0.1	0.4	1.0	-0.2	-0.4	1.0	-0.3	-0.2	-0.5	0.8	0.6	0.4	0.9	0.3	1.2	0.0
Headache pain in last month	0.2	0.3	1.8	0.2	0.5	0.1	0.3	0.2	1.1	0.2	0.5	0.3	0.1	0.2	-1.4	-0.5	1.2	0.5	-0.5	-0.5	-0.2	0.3	0.4	0.1	0.4	0.2	0.6
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.0	-0.7	0.3	-0.7	-0.3	-0.6	-0.8	-0.3	-0.2	-0.5	0.0	-0.4	0.2	1.4	-0.6	-0.2	-0.1	-0.0	-0.2	-0.1	0.0	-1.0	-0.5	0.0	-0.0
Number of full brothers	0.2	0.3	0.9	0.2	-0.5	-0.1	0.5	0.2	-0.7	-1.0	-0.3	-0.1	-0.6	-0.7	-0.7	0.3	0.4	-0.5	0.8	0.7	-0.5	-0.6	-0.7	-0.0	-0.4	-0.5	-0.6
Medication for pain relief, constipation, heartburn	0.2	0.4	2.2	1.1	0.0	1.0	1.5	0.9	0.1	-0.0	0.3	0.9	0.5	0.3	0.9	-0.4	0.3	0.5	-0.4	-0.3	0.5	0.5	0.3	0.8	0.5	0.7	0.3
Medication: Ibuprofen	0.2	0.2	1.0	-0.0	0.8	0.0	-0.4	-0.5	1.0	-0.0	0.4	0.1	0.5	0.4	-0.1	-0.5	0.9	0.0	-0.6	-0.5	0.1	0.3	0.4	-0.1	0.4	0.3	0.2
Mean time to correctly identify matches	0.2	0.4	5.1	0.4	-0.0	0.2	2.2	0.1	1.4	0.5	0.1	0.7	0.5	0.6	0.7	-0.1	-0.3	0.3	-0.4	-0.1	0.1	0.2	0.2	-0.1	0.1	-0.3	0.2
Pulse rate, automated reading	0.2	0.7	6.5	-2.5	0.8	-0.3	0.5	-0.3	0.0	0.1	-0.2	0.4	0.3	1.7	-0.5	0.6	-1.3	0.7	-0.4	-0.4	-0.4	0.2	0.5	-1.6	-0.0	0.3	0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.9	-0.8	-0.2	-0.2	-0.9	0.1	-1.0	-0.3	-0.1	-0.4	-0.5	-0.4	-0.9	-0.1	-0.6	0.2	0.3	0.1	0.3	-0.2	-0.2	-0.5	0.1	0.2	0.0
Hypertension (Self-reported)	0.2	0.7	4.2	1.4	-0.4	-0.3	2.0	-0.1	1.1	0.4	0.5	0.1	0.0	-1.8	-0.1	1.8	-0.6	0.3	-0.3	-0.2	-0.1	0.3	-0.2	0.9	-0.6	0.4	0.3
Illnesses of father: Heart disease	0.2	0.3	1.0	-0.4	1.0	0.2	-0.8	0.6	0.3	0.1	0.4	0.3	0.2	0.2	-0.5	0.2	0.7	0.6	-0.0	-0.6	0.1	0.5	0.2	0.7	0.2	1.0	0.7
Smoking status: Previous	0.2	0.2	1.5	-0.2	0.4	0.0	1.0	0.4	-0.2	-0.7	-0.4	-0.5	-0.2	-0.3	0.3	0.6	0.3	-0.4	0.2	-0.1	-0.3	0.0	-0.3	1.2	-0.4	0.7	-0.2
Average weekly red wine intake	0.2	0.2	3.3	-0.1	0.7	-0.1	-1.8	0.3	0.3	0.7	0.5	0.0	0.3	0.2	-0.3	0.5	0.3	-0.1	0.2	-0.3	0.4	0.1	0.2	0.3	0.1	0.4	-0.1
Miserableness	0.2	0.3	2.5	1.6	-0.1	-0.2	-0.2	0.4	0.6	0.2	0.3	-0.3	0.1	-1.1	0.1	-0.4	1.3	0.2	-0.4	-0.2	-0.1	0.1	0.1	0.6	0.5	-0.0	0.2
Financial situation satisfaction	0.2	0.2	2.1	0.3	0.0	-0.2	1.0	0.8	0.1	0.4	0.0	-0.1	-0.1	0.1	0.2	-0.5	1.5	0.1	-0.3	-0.3	0.3	0.2	0.2	0.5	0.2	-0.1	0.4
Irritability	0.2	0.4	1.3	0.8	0.4	-0.2	1.2	0.6	0.5	0.6	0.3	0.3	0.8	0.2	-0.4	-0.3	1.1	0.7	-0.6	-0.6	0.1	0.5	0.4	0.8	0.8	0.2	0.6
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.9	-1.4	0.1	0.2	-1.2	0.1	-1.0	-0.4	-0.6	-0.2	-0.1	1.7	0.3	-1.3	0.5	-0.5	0.6	0.5	-0.0	-0.5	-0.1	-0.8	0.4	-0.4	-0.6
Heart disease (siblings)	0.2	0.3	1.8	0.0	-0.3	-0.4	-0.6	-0.4	-0.6	-0.5	-0.4	-0.6	-0.3	-1.2	0.1	1.3	-0.2	-0.4	0.6	0.5	-0.5	-0.3	-0.4	-0.3	-0.5	-0.1	-0.4
Pack years of smoking	0.2	0.3	0.8	0.6	-0.1	-0.8	-0.8	-0.9	0.1	0.6	0.0	-0.3	-0.1	0.1	0.5	0.7	0.4	-0.7	0.6	0.5	-0.4	-0.4	-0.6	0.5	-0.8	-0.3	-0.5
Depressed Affect (Nagel 2018)	0.1	0.1	0.8	0.0	0.3	-0.2	0.3	0.7	0.1	0.2	0.2	-0.3	-0.2	-0.5	-0.6	-0.9	0.6	0.0	0.1	0.0	-0.3	-0.2	-0.2	0.6	0.5	-0.2	0.1
Irritable Bowel Disease (IBD)	0.1	0.3	0.9	0.3	0.7	1.0	-0.1	0.4	0.8	0.5	0.3	-0.3	0.8	0.7	0.2	-0.9	0.0	0.2	-0.8	-0.8	0.5	0.6	0.6	0.2	0.6	0.5	0.4
HbA1C	0.1	0.1	0.9	-1.0	-0.2	0.0	-0.3	0.6	0.0	-0.4	-0.3	-0.6	0.0	0.3	-0.3	-0.6	0.4	0.2	0.1	0.0	-0.2	0.0	-0.1	0.7	0.4	-0.2	0.1
Primary Biliary Cirrhosis	0.1	0.1	0.4	-0.5	0.2	0.2	-0.5	0.4	-0.0	0.4	0.0	0.1	0.1	0.3	-0.6	-0.3	-0.6	-0.1	0.3	0.1	-0.4	-0.1	-0.1	0.5	0.2	-0.0	-0.2
Waist Hip Ratio (WHR)	0.1	0.6	3.0	-1.4	0.4	-0.2	-0.9	0.8	-0.6	0.1	-0.7	-0.2	-0.9	1.5	-1.7	0.4	-0.3	-0.6	0.7	0.5	-0.6	-0.6	-0.4	-0.7	-0.7	-0.2	-0.6
Tanning	0.1	1.4	3.1	0.7	1.3	1.3	-0.5	1.5	0.6	0.9	1.1	1.0	1.0	1.8	-1.6	-0.8	1.5	0.8	-0.6	-1.1	1.2	1.1	0.9	1.7	0.9	1.8	0.9
Hand grip strength (left)	0.1	0.3	2.0	0.9	0.1	0.4	-0.8	-0.1	-0.2	0.2	0.2	0.0	0.4	-0.4	0.1	0.4	1.4	0.1	-0.2	-0.4	0.7	0.4	0.1	0.5	-0.1	0.9	0.3
Medication for hormone replacement therapy	0.1	0.1	0.6	0.1	-0.1	-0.5	0.5	-0.5	0.5	-0.1	-0.1	-0.2	-0.0	0.2	-0.3	0.6	-0.3	-0.0	0.1	0.0	-0.6	-0.1	-0.2	-0.8	-0.5	-0.2	0.0
Vitamin and mineral supplements	0.1	0.1	1.2	1.1	-0.1	0.1	-0.2	0.2	-0.4	0.3	-0.1	0.0	0.4	-0.2	0.3	0.9	-0.1	0.1	-0.2	-0.0	0.0	0.2	0.1	0.0	-0.4	0.1	0.1
Townsend deprivation index at recruitment	0.1	0.1	1.1	-0.1	0.0	0.0	1.0	-0.4	0.6	0.2	0.1	0.1	-0.3	-0.0	-0.5	0.2	0.2	0.1	-0.0	-0.1	0.1	0.0	-0.1	-0.3	-0.3	0.1	0.2
Relative age voice broke	0.1	0.1	1.3	0.1	-0.3	0.1	-0.5	-0.0	0.3	-0.5	-0.1	-0.4	-0.4	-0.3	1.1	-0.4	0.0	-0.2	0.1	0.0	0.1	-0.2	-0.1	-0.5	-0.1	-0.0	-0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.6	-0.7	-0.2	-0.1	0.1	0.3	0.3	-0.5	-0.5	-0.1	-0.3	0.1	0.5	0.3	-0.8	-0.3	0.2	0.4	-0.3	-0.3	-0.3	0.0	-0.5	-0.4	-0.4
Nervous feelings	0.1	0.2	1.0	0.6	0.3	-0.0	0.6	-0.1	-0.6	0.6	0.5	0.3	0.4	0.3	0.1	-1.0	0.8	0.3	-0.4	-0.1	0.4	0.2	0.3	-0.4	0.6	-0.0	0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.8	0.2	-0.2	-0.3	0.9	-0.8	0.2	-0.1	0.1	-0.0	0.2	-0.0	-0.2	0.9	-0.5	-0.0	0.0	0.1	0.1	0.0	0.0	-0.7	-0.1	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.7	-0.4	0.4	0.7	0.9	1.0	0.4	0.1	0.3	0.4	-0.0	0.9	-0.3	-0.8	0.2	0.2	-0.3	-0.3	0.4	0.4	0.1	1.3	0.3	0.7	0.3
Mouth/teeth dental problems	0.1	0.1	0.3	0.3	-0.3	0.2	-0.5	0.5	0.4	-0.3	-0.1	0.3	-0.1	0.2	-0.4	-0.0	-0.0	-0.4	0.2	0.0	-0.1	-0.1	-0.1	0.2	-0.2	-0.3	-0.4
Pain all over the body in last month	0.1	0.1	0.2	-0.2	-0.2	-0.3	0.3	0.2	-0.4	0.2	0.1	-0.0	0.1	-0.3	-0.5	0.4	0.1	0.0	-0.3	0.2	0.3	0.1	0.0	0.2	0.0	-0.4	0.0
Medication: Simvastatin	0.1	0.1	1.2	0.1	0.1	-0.2	-1.1	0.1	-0.0	-0.0	0.0	-0.3	-0.3	0.1	-0.5	0.6	0.4	-0.4	0.4	0.3	-0.0	-0.2	-0.4	0.2	-0.5	0.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.9	0.6	-0.3	-0.6	0.3	-0.4	0.5	0.1	0.0	-0.3	0.0	-0.5	-0.5	1.0	0.7	0.0	-0.2	0.1	-0.2	0.0	0.0	-0.7	-0.3	-0.4	0.1
Hair/balding pattern: Pattern 4	0.1	0.3	1.4	0.7	0.2	0.3	0.8	-0.4	-0.6	0.3	0.4	0.0	0.6	-0.3	-0.5	1.2	-0.1	0.5	-0.6	-0.4	0.5	0.4	0.7	-1.0	-0.1	0.5	0.5
Pulse wave peak to peak time	0.1	0.1	0.7	-0.1	0.3	0.5	0.4	-0.3	0.7	0.6	0.2	0.1	0.5	0.9	-0.0	-0.1	-0.3	0.1	-0.2	-0.1	0.7	0.3	0.3	0.1	0.2	0.1	0.1
Qualifications: College or University degree	0.1	0.3	1.0	0.8	-0.7	1.0	-0.0	0.3	0.3	-0.0	-0.2	0.4	-0.5	0.8	-0.7	-0.7	0.1	-0.5	0.5	0.6	-0.4	-0.7	-0.3	-0.9	-0.3	-0.8	-0.7
Medication: Seretide 50 evohaler	0.1	0.2	0.8	-0.3	0.6	0.3	-0.4	0.4	-0.1	0.6	0.3	0.4	0.4	0.9	-0.3	-0.3	0.1	-0.1	-0.2	-0.2	0.5	0.3	0.4	-0.1	0.2	0.6	0.1
Alcohol intake frequency.	0.1	0.2	1.0	-0.5	0.1	-0.8	0.1	-0.8	-0.8	0.2	0.1	-0.6	-0.0	-0.2	0.3	1.0	-1.0	-0.2	0.1	0.1	0.1	0.1	-0.2	-0.1	-0.3	0.0	0.0
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.7	0.3	0.2	0.7	-0.4	0.0	0.6	0.6	0.2	-0.0	0.3	0.4	-0.8	0.6	-0.4	0.1	0.0	-0.5	0.3	0.2	0.2	-0.0	-0.2	0.4	0.0
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.1	0.2	0.1	-0.2	-0.1	0.3	-0.1	0.4	0.0	0.4	-0.4	0.3	0.4	0.3	-0.0	-0.3	-0.4	0.3	0.3	0.3	-0.3	-0.0	0.3	0.2
Loneliness, isolation	0.1	0.2	1.3	0.1	-0.0	-0.1	0.3	0.1	-0.1	0.6	0.1	-0.2	-0.5	0.3	-0.8	-1.1	0.7	-0.1	0.1	0.1	-0.2	-0.1	-0.2	0.7	0.4	-0.1	-0.0
Friendships satisfaction	0.1	0.1	0.4	0.2	-0.2	0.1	0.4	0.2	0.6	0.5	-0.1	-0.4	-0.2	-0.0	-0.6	-0.4	0.4	-0.1	0.4	0.2	-0.1	-0.2	-0.3	0.7	0.1	-0.3	-0.2
Osteoarthritis (self-reported)	0.1	0.2	0.8	-0.2	-0.4	-0.9	-0.6	-0.4	-0.1	-0.2	-0.1	-0.3	-0.2	-0.7	-0.5	0.9	-0.3	-0.2	0.1	0.2	0.0	-0.2	-0.2	0.1	-0.4	-0.4	-0.2
Mother’s age at death	0.1	0.1	0.6	0.2	-0.3	0.0	0.7	-0.0	-0.2	-0.3	-0.4	-0.1	-0.3	0.2	0.4	0.2	-0.8	-0.0	0.2	0.2	-0.3	-0.2	-0.3	-0.3	-0.4	-0.1	-0.2
Medication: Blood pressure	0.1	0.2	1.9	-0.1	0.2	-0.6	-0.2	0.6	-0.0	0.3	0.1	-0.1	-0.2	-0.3	-0.0	0.8	-0.0	0.0	0.1	-0.2	-0.3	0.1	-0.3	1.4	-0.3	0.1	0.1
Medication: Bendroflumethiazide	0.1	0.2	1.1	0.2	-0.0	-0.7	-0.9	0.1	-0.7	0.2	0.3	-0.2	0.0	-1.0	-0.5	0.7	-0.8	0.5	-0.4	-0.1	0.3	0.1	0.1	-0.4	-0.0	0.0	0.4
Cholesterol lowering medication	0.1	0.1	0.8	-0.9	0.3	-0.4	0.5	-0.0	-0.1	-0.0	-0.1	-0.3	-0.5	0.1	-0.1	0.1	-0.3	-0.1	0.1	-0.0	-0.4	-0.4	-0.2	-0.6	-0.2	-0.1	0.0
Blood Red Count	0.0	0.2	1.3	0.2	0.3	0.2	0.3	-1.1	-0.3	-0.3	0.4	-0.2	0.6	0.4	0.4	1.0	0.0	0.0	-0.1	-0.2	0.7	0.4	0.6	-0.7	-0.1	0.9	0.2
Hair Pigment	0.0	0.5	2.4	0.2	0.7	-0.1	1.1	0.0	0.9	1.1	0.6	0.8	0.4	1.3	-1.5	-0.3	-0.4	0.6	-0.5	-0.7	0.4	0.4	0.5	0.4	0.4	0.4	0.6
Impedance of leg (right)	0.0	0.2	2.1	1.4	-0.1	0.4	-0.2	0.2	0.3	0.1	0.3	0.7	0.8	0.5	0.1	-0.3	0.3	0.5	-0.7	-0.0	0.2	0.4	0.4	-0.3	0.3	-0.2	0.3
Impedance of leg (left)	0.0	0.1	0.6	0.6	-0.1	0.0	-0.2	-0.1	0.1	-0.1	-0.0	0.5	0.5	0.2	0.1	-0.1	-0.0	0.4	-0.5	0.2	-0.4	0.1	0.1	-0.8	0.1	-0.6	0.2

Hub : Genes

LRRFIP2

Models

Trait associations