Best TWAS P=5.54e-08 · Best GWAS P=6.36e-07 conditioned to 0.403
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | ITIH4-AS1 | 0.11 | 0.05 | enet | 10 | 0.02 | 5.1e-02 | 4.8 | -5.3 | 1.2e-07 | -0.82 | 0.04 | 0.77 | FALSE |
| 2 | GTEx | Esophagus Muscularis | NEK4 | 0.06 | 0.00 | lasso | 3 | 0.02 | 2.8e-02 | 4.6 | 5.4 | 5.5e-08 | 0.83 | 0.10 | 0.76 | TRUE |
| 3 | GTEx | Muscle Skeletal | ITIH4-AS1 | 0.06 | 0.03 | lasso | 4 | 0.06 | 2.3e-06 | -3.7 | -5.1 | 2.8e-07 | -0.82 | 0.15 | 0.82 | FALSE |