[Hub]/) : Traits : Bipolar Disorder or Schizophrenia :

chr8:37,329,315-38,932,193

Best TWAS P=4.46e-11 · Best GWAS P=8.41e-09 conditioned to 0.274

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex STAR 0.05 0.00 blup 247 0.02 1.2e-03 -5.0 -5.1 2.7e-07 0.73 0.07 0.80 FALSE
2 GTEx Adrenal Gland DDHD2 0.25 0.21 lasso 2 0.19 1.7e-07 -5.5 -5.6 2.5e-08 0.96 0.04 0.96 FALSE
3 GTEx Adrenal Gland LSM1 0.17 0.10 enet 22 0.17 1.1e-06 -5.3 5.3 1.4e-07 -0.82 0.04 0.94 FALSE
4 GTEx Adrenal Gland RP11-90P5.2 0.18 0.18 enet 24 0.22 2.0e-08 -5.2 5.1 2.6e-07 -0.76 0.05 0.93 FALSE
5 GTEx Artery Tibial DDHD2 0.07 0.07 lasso 2 0.05 7.3e-05 -5.5 -5.5 3.9e-08 0.96 0.04 0.96 FALSE
6 GTEx Brain Cerebellum DDHD2 0.18 0.05 lasso 7 0.05 1.5e-02 -5.7 -5.4 5.7e-08 0.81 0.04 0.87 FALSE
7 GTEx Breast Mammary Tissue RP11-350N15.5 0.08 0.03 enet 12 0.02 1.9e-02 -3.9 5.3 9.5e-08 -0.90 0.04 0.88 FALSE
8 GTEx Breast Mammary Tissue (Female) RP11-350N15.5 0.12 0.10 lasso 2 0.07 3.9e-03 -5.6 5.7 1.1e-08 -0.97 0.04 0.81 FALSE
9 GTEx Colon Sigmoid DDHD2 0.15 0.15 lasso 3 0.12 7.5e-05 -5.7 -5.7 1.2e-08 0.93 0.04 0.92 FALSE
10 GTEx Esophagus Mucosa DDHD2 0.09 0.02 lasso 3 0.02 8.4e-03 -5.4 -5.3 1.2e-07 0.84 0.04 0.89 FALSE
11 GTEx Esophagus Muscularis DDHD2 0.12 0.13 lasso 2 0.12 5.7e-08 -5.2 -5.3 1.5e-07 0.91 0.07 0.93 FALSE
12 GTEx Pituitary DDHD2 0.25 0.22 lasso 3 0.17 3.9e-05 -5.6 -5.3 1.2e-07 0.89 0.04 0.90 FALSE
13 GTEx Prostate DDHD2 0.38 0.18 lasso 7 0.17 5.4e-05 -5.3 -5.8 5.8e-09 0.91 0.05 0.94 FALSE
14 GTEx Spleen DDHD2 0.17 0.17 lasso 2 0.11 7.8e-04 -5.5 -5.6 2.8e-08 0.95 0.04 0.88 FALSE
15 GTEx Stomach DDHD2 0.13 0.06 lasso 2 0.06 1.1e-03 -5.6 -5.6 2.2e-08 0.93 0.04 0.88 FALSE
16 GTEx Thyroid DDHD2 0.11 0.10 lasso 4 0.09 3.8e-07 -5.2 -5.3 1.2e-07 0.91 0.06 0.94 FALSE
17 NTR Blood BAG4 0.01 0.01 blup 253 0.01 3.9e-03 -5.2 5.1 2.9e-07 -0.92 0.05 0.93 FALSE
18 ROSMAP Brain Pre-frontal Cortex PPAPDC1B 0.06 0.08 enet 14 0.09 4.0e-11 -5.7 -5.7 1.0e-08 0.97 0.04 0.96 FALSE
19 ROSMAP Brain Pre-frontal Cortex LSM1 0.09 0.16 lasso 6 0.16 7.3e-20 -5.4 5.4 5.1e-08 -0.93 0.11 0.89 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma DDHD2 0.01 0.01 blup 21 0.01 2.3e-03 -5.5 -6.2 4.8e-10 0.94 0.01 0.77 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BAG4 0.04 0.03 lasso 1 0.02 1.6e-03 -5.2 5.2 1.8e-07 -0.84 0.04 0.57 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DDHD2 0.03 0.03 blup 21 0.03 3.5e-04 -5.5 -6.0 1.8e-09 0.95 0.02 0.98 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPAPDC1B 0.02 0.00 blup 18 0.01 4.2e-02 -5.4 -6.6 4.5e-11 0.93 0.01 0.53 TRUE
24 The Cancer Genome Atlas Pancreatic Adenocarcinoma DDHD2 0.07 0.05 blup 21 0.05 2.7e-03 -5.7 -5.9 3.0e-09 0.94 0.02 0.78 FALSE
25 The Cancer Genome Atlas Pancreatic Adenocarcinoma PPAPDC1B 0.14 0.06 enet 15 0.08 2.7e-04 -5.7 -5.8 5.3e-09 0.72 0.01 0.90 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma DDHD2 0.11 0.08 lasso 3 0.08 1.9e-08 -5.7 -5.7 1.4e-08 0.93 0.01 0.99 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma DDHD2 0.02 0.01 blup 21 0.01 2.4e-02 -5.7 -5.6 2.6e-08 0.95 0.01 0.77 FALSE